Krystal Biotech (KRYS) Operating Expenses (2016 - 2026)
Krystal Biotech's (KRYS) quarterly Operating Expenses came in at $62.7 million in Q1 2026, up 20.68% year-on-year from $51.9 million in Q1 2025, and little changed quarter-over-quarter from $62.8 million in Q4 2025.
Krystal Biotech (KRYS) Operating Expenses (2016 - 2026) Analysis & Trends
Krystal Biotech has disclosed Operating Expenses across 11 years of filings, most recently posting $62.7 million for Q1 2026.
- Operating Expenses for Q1 2026 came in at $62.7 million, up 20.68% year-over-year; the trailing twelve-month figure through Mar 2026 was $238.7 million (up 6.18% YoY), and the FY2025 annual result was $227.8 million, up 1.36% from the prior year.
- Operating Expenses came in at $62.7 million for Q1 2026 at Krystal Biotech, roughly flat from $62.8 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $62.8 million in Q4 2025 to a low of $28.8 million in Q2 2022.
- The 5-year median for Operating Expenses is $50.2 million (2022), against an average of $48.3 million.
- Across the five-year window, Operating Expenses jumped 249.91% in 2022 and dropped 8.07% in 2025, its largest moves.
- Krystal Biotech's Operating Expenses stood at $34.8 million in 2022, then grew by 11.86% to $38.9 million in 2023, then grew by 27.94% to $49.8 million in 2024, then gained by 26.27% to $62.8 million in 2025, then decreased by 0.27% to $62.7 million in 2026.
- The last three Operating Expenses figures came in at $62.7 million (Q1 2026), $62.8 million (Q4 2025), and $56.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | Krystal Biotech | 10.23 Bn | 9.41 Bn | 110.03 Mn | 62.67 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 62.67 Mn |
| Dec 31, 2025 | 62.84 Mn |
| Sep 30, 2025 | 56.43 Mn |
| Jun 30, 2025 | 56.74 Mn |
| Mar 31, 2025 | 51.93 Mn |
| Dec 31, 2024 | 49.76 Mn |
| Sep 30, 2024 | 61.37 Mn |
| Jun 30, 2024 | 61.72 Mn |
| Mar 31, 2024 | 51.93 Mn |
| Dec 31, 2023 | 38.90 Mn |
| Sep 30, 2023 | 34.55 Mn |
| Jun 30, 2023 | 38.05 Mn |
| Mar 31, 2023 | 48.82 Mn |
| Dec 31, 2022 | 34.77 Mn |
| Sep 30, 2022 | 31.45 Mn |
| Jun 30, 2022 | 28.75 Mn |
| Mar 31, 2022 | 50.22 Mn |
| Dec 31, 2021 | 21.88 Mn |
| Sep 30, 2021 | 15.65 Mn |
| Jun 30, 2021 | 16.39 Mn |