Krystal Biotech (KRYS) Operating Expenses (2016 - 2026)

Krystal Biotech (KRYS) reported Operating Expenses of $62.7 million for Q1 2026, up 20.68% on a YoY basis from $51.9 million in Q1 2025, and little changed sequentially from $62.8 million in Q4 2025.

Krystal Biotech (KRYS) Operating Expenses (2016 - 2026) Analysis & Trends

Krystal Biotech (KRYS) has 11 years of Operating Expenses data on file, last reported at $62.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses rose 20.68% year-over-year to $62.7 million; the trailing twelve-month figure through Mar 2026 stood at $238.7 million (up 6.18% YoY), and the FY2025 full-year result was $227.8 million, up 1.36% from the prior year.
  • Operating Expenses held at $62.7 million in Q1 2026, from $62.8 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $62.8 million in Q4 2025 to a low of $28.8 million in Q2 2022.
  • A 5-year average of $48.3 million and a median of $50.2 million in 2022 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses jumped 249.91% in 2022 and dropped 8.07% in 2025, its largest moves.
  • Tracing KRYS's Operating Expenses over 5 years: stood at $34.8 million in 2022, then climbed by 11.86% to $38.9 million in 2023, then climbed by 27.94% to $49.8 million in 2024, then rose by 26.27% to $62.8 million in 2025, then retreated by 0.27% to $62.7 million in 2026.
  • Business Quant data shows KRYS's Operating Expenses at $62.7 million in Q1 2026, $62.8 million in Q4 2025, and $56.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Krystal Biotech 9.84 Bn 9.02 Bn 110.08 Mn 62.67 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 62.67 Mn
Dec 31, 2025 62.84 Mn
Sep 30, 2025 56.43 Mn
Jun 30, 2025 56.74 Mn
Mar 31, 2025 51.93 Mn
Dec 31, 2024 49.76 Mn
Sep 30, 2024 61.37 Mn
Jun 30, 2024 61.72 Mn
Mar 31, 2024 51.93 Mn
Dec 31, 2023 38.90 Mn
Sep 30, 2023 34.55 Mn
Jun 30, 2023 38.05 Mn
Mar 31, 2023 48.82 Mn
Dec 31, 2022 34.77 Mn
Sep 30, 2022 31.45 Mn
Jun 30, 2022 28.75 Mn
Mar 31, 2022 50.22 Mn
Dec 31, 2021 21.88 Mn
Sep 30, 2021 15.65 Mn
Jun 30, 2021 16.39 Mn