Krystal Biotech (KRYS) Operating Expenses (2016 - 2026)

Krystal Biotech's (KRYS) quarterly Operating Expenses came in at $62.7 million in Q1 2026, up 20.68% year-on-year from $51.9 million in Q1 2025, and little changed quarter-over-quarter from $62.8 million in Q4 2025.

Krystal Biotech (KRYS) Operating Expenses (2016 - 2026) Analysis & Trends

Krystal Biotech has disclosed Operating Expenses across 11 years of filings, most recently posting $62.7 million for Q1 2026.

  • Operating Expenses for Q1 2026 came in at $62.7 million, up 20.68% year-over-year; the trailing twelve-month figure through Mar 2026 was $238.7 million (up 6.18% YoY), and the FY2025 annual result was $227.8 million, up 1.36% from the prior year.
  • Operating Expenses came in at $62.7 million for Q1 2026 at Krystal Biotech, roughly flat from $62.8 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $62.8 million in Q4 2025 to a low of $28.8 million in Q2 2022.
  • The 5-year median for Operating Expenses is $50.2 million (2022), against an average of $48.3 million.
  • Across the five-year window, Operating Expenses jumped 249.91% in 2022 and dropped 8.07% in 2025, its largest moves.
  • Krystal Biotech's Operating Expenses stood at $34.8 million in 2022, then grew by 11.86% to $38.9 million in 2023, then grew by 27.94% to $49.8 million in 2024, then gained by 26.27% to $62.8 million in 2025, then decreased by 0.27% to $62.7 million in 2026.
  • The last three Operating Expenses figures came in at $62.7 million (Q1 2026), $62.8 million (Q4 2025), and $56.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.33 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -138.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 574,669.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.96 Bn 91.96 Bn - -67.40 Mn
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn 62.67 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 62.67 Mn
Dec 31, 2025 62.84 Mn
Sep 30, 2025 56.43 Mn
Jun 30, 2025 56.74 Mn
Mar 31, 2025 51.93 Mn
Dec 31, 2024 49.76 Mn
Sep 30, 2024 61.37 Mn
Jun 30, 2024 61.72 Mn
Mar 31, 2024 51.93 Mn
Dec 31, 2023 38.90 Mn
Sep 30, 2023 34.55 Mn
Jun 30, 2023 38.05 Mn
Mar 31, 2023 48.82 Mn
Dec 31, 2022 34.77 Mn
Sep 30, 2022 31.45 Mn
Jun 30, 2022 28.75 Mn
Mar 31, 2022 50.22 Mn
Dec 31, 2021 21.88 Mn
Sep 30, 2021 15.65 Mn
Jun 30, 2021 16.39 Mn