Krystal Biotech (KRYS) Operating Expenses (2016 - 2026)
Krystal Biotech (KRYS) posted quarterly Operating Expenses of $60.8 million for Q2 2026, up 7.35% year-over-year from $56.6 million in Q2 2025, and down 2.97% on a QoQ basis from $62.7 million in Q1 2026.
Krystal Biotech (KRYS) Operating Expenses (2016 - 2026) Analysis & Trends
Krystal Biotech has reported Operating Expenses for 11 years, with the latest figure at $60.8 million in Q2 2026.
- Operating Expenses for Q2 2026 came in at $60.8 million, up 7.35% year-over-year; the trailing twelve-month figure through Jun 2026 was $242.7 million (up 10.48% YoY), and the FY2025 annual result was $227.8 million, up 1.36% from the prior year.
- Operating Expenses declined to $60.8 million in Q2 2026, from $62.7 million in the prior quarter.
- Over five years, Operating Expenses peaked at $62.8 million in Q4 2025 and troughed at $28.8 million in Q2 2022.
- A 5-year average of $49.0 million and a median of $51.1 million in 2022 frame the typical range for Operating Expenses.
- The widest annual swing landed in 2022, when Operating Expenses jumped 249.91%; it then fell 8.22% in 2025.
- A 5-year view of Operating Expenses shows it stood at $34.8 million in 2022, then rose by 11.86% to $38.9 million in 2023, then rose by 27.94% to $49.8 million in 2024, then climbed by 26.27% to $62.8 million in 2025, then dropped by 3.23% to $60.8 million in 2026.
- Per Business Quant data, the three most recent Operating Expenses figures were $60.8 million in Q2 2026, $62.7 million in Q1 2026, and $62.8 million in Q4 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Krystal Biotech | 9.83 Bn | 8.99 Bn | 112.79 Mn | 60.81 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 60.81 Mn |
| Mar 31, 2026 | 62.67 Mn |
| Dec 31, 2025 | 62.84 Mn |
| Sep 30, 2025 | 56.43 Mn |
| Jun 30, 2025 | 56.74 Mn |
| Mar 31, 2025 | 51.93 Mn |
| Dec 31, 2024 | 49.76 Mn |
| Sep 30, 2024 | 61.37 Mn |
| Jun 30, 2024 | 61.72 Mn |
| Mar 31, 2024 | 51.93 Mn |
| Dec 31, 2023 | 38.90 Mn |
| Sep 30, 2023 | 34.55 Mn |
| Jun 30, 2023 | 38.05 Mn |
| Mar 31, 2023 | 48.82 Mn |
| Dec 31, 2022 | 34.77 Mn |
| Sep 30, 2022 | 31.45 Mn |
| Jun 30, 2022 | 28.75 Mn |
| Mar 31, 2022 | 50.22 Mn |
| Dec 31, 2021 | 21.88 Mn |
| Sep 30, 2021 | 15.65 Mn |