International Stem Cell ISCO
OTC ISCO
$0.33 +0.00 (+0.00%)
At close: Sep 8, 2026 · 4:00 PM EDT

International Stem Cell (ISCO) EV to FCF (2010 - 2025)

International Stem Cell's (ISCO) quarterly EV to FCF came in at 4.4 in Q4 2025, down 44.03% year-over-year from 7.86 in Q4 2024, and up 171.45% quarter-over-quarter from 1.62 in Q3 2025.

Analysis

International Stem Cell (ISCO) EV to FCF (2010 - 2025) Analysis & Trends

International Stem Cell (ISCO) has reported EV to FCF for 16 consecutive years, with 4.4 the latest figure, recorded in Q4 2025.

  • On a quarterly basis, EV to FCF fell 44.03% year-over-year to 4.4 in Q4 2025; TTM through Dec 2025 was 3.65, a 194.61% decrease from a year earlier, with the FY2025 full-year figure at 3.65, down 194.61% from the prior year.
  • EV to FCF was 4.4 for Q4 2025 at International Stem Cell, up from 1.62 in the prior quarter.
  • Over five years, EV to FCF peaked at 27.33 in Q3 2022 and troughed at 149.74 in Q1 2022.
  • A 5-year average of 7.4 and a median of 0.93 in 2023 frame the typical range for EV to FCF.
  • Across the five-year window, EV to FCF slumped 1245.0% in 2022 and jumped 1173.34% in 2024, its largest moves.
  • Over 5 years, EV to FCF stood at 11.02 in 2021, then soared by 180.3% to 8.85 in 2022, then sank by 177.78% to 6.88 in 2023, then jumped by 214.27% to 7.86 in 2024, then tumbled by 44.03% to 4.4 in 2025.
  • The last three EV to FCF figures came in at 4.4 (Q4 2025), 1.62 (Q3 2025), and 1.09 (Q2 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Krystal Biotech 10.27 Bn 9.43 Bn 112.79 Mn
2 CRISPR Therapeutics AG 5.17 Bn 5.17 Bn -
3 Iovance Biotherapeutics 3.79 Bn 3.49 Bn 55.72 Mn
4 Legend Biotech 3.68 Bn 2.71 Bn 251.50 Mn
5 uniQure 3.05 Bn 3.05 Bn 5.49 Mn
6 Beam Therapeutics 2.65 Bn 2.65 Bn -
7 Precigen 2.44 Bn 2.44 Bn 52.17 Mn
8 Sarepta Therapeutics 2.33 Bn 1.53 Bn 251.87 Mn
9 Vericel 1.99 Bn 1.83 Bn 56.40 Mn
10 International Stem Cell 2.84 Mn 1.75 Mn 1.46 Mn
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 4.40
Sep 30, 2025 1.62
Jun 30, 2025 -1.09
Mar 31, 2025 -2.21
Dec 31, 2024 7.86
Sep 30, 2024 -3.76
Jun 30, 2024 8.35
Mar 31, 2024 2.91
Dec 31, 2023 -6.88
Sep 30, 2023 -9.78
Jun 30, 2023 -0.78
Mar 31, 2023 2.48
Dec 31, 2022 8.85
Sep 30, 2022 27.33
Jun 30, 2022 14.04
Mar 31, 2022 -149.74
Dec 31, 2021 -11.02
Sep 30, 2021 -16.68
Jun 30, 2021 -12.71
Mar 31, 2021 -11.13