Iovance Biotherapeutics (IOVA) Operating Margin (2023 - 2026)
Iovance Biotherapeutics (IOVA) recorded Operating Margin of -52.26% in Q2 2026, up 137.51 percentage points from -189.78% a year earlier and up 61.19 percentage points from the prior quarter.
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Analysis
Iovance Biotherapeutics (IOVA) Operating Margin (2023 - 2026) Analysis & Trends
On a TTM basis, Iovance Biotherapeutics' Operating Margin came in at -92.72% as of Jun 30, 2026, up 77.30 percentage points year-over-year; for FY2025, it was -153.08%, up 87.85 percentage points from FY2024.
- Across earlier years, Operating Margin came in at -240.92% in FY2024 (+38494.07 pp) and -38734.99% in FY2023.
- The Q2 2026 figure is the highest quarterly Operating Margin in data going back to Q2 2023.
- On a year-over-year basis, Operating Margin has increased for nine consecutive quarters, with an average year-over-year change of +8349.36 percentage points over the last eight quarters.
- The year-over-year gain in Operating Margin has ranged between 11.42 percentage points (Q3 2025) and 45926.99 percentage points (Q2 2024) over the last five years.
- Per Business Quant, the preceding three quarters came in at -113.46% (Q1 2026), -84.66% (Q4 2025) and -140.69% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Iovance Biotherapeutics | 4.98 Bn | 3.77 Bn | 55.72 Mn | -52.26% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -52.26% |
| Mar 31, 2026 | -113.46% |
| Dec 31, 2025 | -84.66% |
| Sep 30, 2025 | -140.69% |
| Jun 30, 2025 | -189.78% |
| Mar 31, 2025 | -245.76% |
| Dec 31, 2024 | -117.48% |
| Sep 30, 2024 | -152.11% |
| Jun 30, 2024 | -327.63% |
| Mar 31, 2024 | -16,464.62% |
| Dec 31, 2023 | -25,156.85% |
| Sep 30, 2023 | -25,236.89% |
| Jun 30, 2023 | -46,254.62% |
API Access
Iovance Biotherapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=IOVA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "IOVA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=IOVA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();