Structure Therapeutics (GPCR) Operating Expenses (2022 - 2026)

Quarterly Operating Expenses rose 58.72% to $89.4 million in Q1 2026 from the year-ago period, while the trailing twelve-month figure was $209.6 million through Mar 2026, up 14.85% year-over-year, with the annual reading at $176.6 million for FY2025, 11.59% up from the prior year.

Structure Therapeutics' Operating Expenses history spans 5 years, with the latest figure at $89.4 million for Q1 2026.

  • Operating Expenses came in at $89.4 million for Q1 2026, up from -$24.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $89.4 million in Q1 2026 to a low of -$24.0 million in Q4 2025.
  • The 5-year median for Operating Expenses is $31.0 million (2023), against an average of $34.1 million.
  • Year-over-year, Operating Expenses soared 139.23% in 2023 and then tumbled 150.97% in 2025.
  • Structure Therapeutics' Operating Expenses stood at $13.0 million in 2022, then skyrocketed by 139.23% to $31.0 million in 2023, then skyrocketed by 51.84% to $47.1 million in 2024, then tumbled by 150.97% to -$24.0 million in 2025, then surged by 472.58% to $89.4 million in 2026.
  • Per Business Quant, the three most recent readings for GPCR's Operating Expenses are $89.4 million (Q1 2026), -$24.0 million (Q4 2025), and $73.8 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 2.97 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - 4.33 Mn
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 1.85 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 2.96 Bn
8 Evaxion A 65.12 Bn 65.10 Bn - -3.82 Mn
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 898.54 Mn
10 Structure Therapeutics 8.43 Bn 8.43 Bn - 89.38 Mn

Historic Data

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DateValue
Mar 31, 2026 89.38 Mn
Dec 31, 2025 -23.99 Mn
Sep 30, 2025 73.79 Mn
Jun 30, 2025 70.45 Mn
Mar 31, 2025 56.31 Mn
Dec 31, 2024 47.06 Mn
Sep 30, 2024 45.84 Mn
Jun 30, 2024 33.32 Mn
Mar 31, 2024 32.02 Mn
Dec 31, 2023 30.99 Mn
Sep 30, 2023 26.15 Mn
Jun 30, 2023 25.99 Mn
Mar 31, 2023 19.65 Mn
Dec 31, 2022 12.96 Mn
Sep 30, 2022 12.69 Mn
Jun 30, 2022 13.96 Mn
Mar 31, 2022 12.95 Mn