Structure Therapeutics (GPCR) Operating Expenses (2022 - 2026)

Structure Therapeutics' (GPCR) quarterly Operating Expenses came in at $89.4 million in Q1 2026, up 58.72% year-on-year from $56.3 million in Q1 2025, and up 472.58% quarter-over-quarter from -$24.0 million in Q4 2025.

Structure Therapeutics (GPCR) Operating Expenses (2022 - 2026) Analysis & Trends

Structure Therapeutics' Operating Expenses history runs 5 years deep, the most recent figure standing at $89.4 million for Q1 2026.

  • On a quarterly basis, Operating Expenses rose 58.72% year-over-year to $89.4 million in Q1 2026; TTM through Mar 2026 was $209.6 million, a 14.85% increase from a year earlier, with the FY2025 full-year figure at $176.6 million, up 11.59% from the prior year.
  • Operating Expenses climbed to $89.4 million in Q1 2026 per GPCR's latest filing, from -$24.0 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $89.4 million in Q1 2026 and bottomed at -$24.0 million in Q4 2025.
  • The 5-year median for Operating Expenses is $31.0 million (2023), against an average of $34.1 million.
  • Across the five-year window, Operating Expenses soared 139.23% in 2023 and slumped 150.97% in 2025, its largest moves.
  • Year by year, Operating Expenses stood at $13.0 million in 2022, then surged by 139.23% to $31.0 million in 2023, then surged by 51.84% to $47.1 million in 2024, then tumbled by 150.97% to -$24.0 million in 2025, then soared by 472.58% to $89.4 million in 2026.
  • Per Business Quant, the three latest GPCR Operating Expenses figures stand at $89.4 million (Q1 2026), -$24.0 million (Q4 2025), and $73.8 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Structure Therapeutics 11.04 Bn 11.04 Bn - 89.38 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 89.38 Mn
Dec 31, 2025 -23.99 Mn
Sep 30, 2025 73.79 Mn
Jun 30, 2025 70.45 Mn
Mar 31, 2025 56.31 Mn
Dec 31, 2024 47.06 Mn
Sep 30, 2024 45.84 Mn
Jun 30, 2024 33.32 Mn
Mar 31, 2024 32.02 Mn
Dec 31, 2023 30.99 Mn
Sep 30, 2023 26.15 Mn
Jun 30, 2023 25.99 Mn
Mar 31, 2023 19.65 Mn
Dec 31, 2022 12.96 Mn
Sep 30, 2022 12.69 Mn
Jun 30, 2022 13.96 Mn
Mar 31, 2022 12.95 Mn