Structure Therapeutics (GPCR) Operating Expenses (2022 - 2026)

Structure Therapeutics (GPCR) recorded quarterly Operating Expenses of $89.4 million in Q1 2026, up 472.58% quarter-over-quarter from -$24.0 million in Q4 2025, and up 58.72% on a YoY basis from $56.3 million in Q1 2025.

Structure Therapeutics (GPCR) Operating Expenses (2022 - 2026) Analysis & Trends

Structure Therapeutics' Operating Expenses history runs 5 years deep, the most recent figure standing at $89.4 million for Q1 2026.

  • In Q1 2026, Operating Expenses rose 58.72% year-over-year to $89.4 million; the TTM figure through Mar 2026 stood at $209.6 million (up 14.85% YoY), while the FY2025 annual figure was $176.6 million, up 11.59% from the prior year.
  • Operating Expenses was $89.4 million for Q1 2026 at Structure Therapeutics, up from -$24.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $89.4 million in Q1 2026 to a low of -$24.0 million in Q4 2025.
  • Historically, Operating Expenses has averaged $34.1 million across 5 years, with a median of $31.0 million in 2023.
  • The sharpest annual moves came in 2023 and 2025: Operating Expenses jumped 139.23% in 2023, then slumped 150.97% in 2025.
  • A 5-year view of Operating Expenses shows it stood at $13.0 million in 2022, then surged by 139.23% to $31.0 million in 2023, then surged by 51.84% to $47.1 million in 2024, then sank by 150.97% to -$24.0 million in 2025, then soared by 472.58% to $89.4 million in 2026.
  • The last three Operating Expenses figures came in at $89.4 million (Q1 2026), -$24.0 million (Q4 2025), and $73.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - 4.33 Mn
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - 2.97 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - 15.76 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - 574,669.00
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.85 Bn
9 Abivax 90.15 Bn 90.15 Bn - -67.40 Mn
10 Structure Therapeutics 9.35 Bn 9.35 Bn - 89.38 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 89.38 Mn
Dec 31, 2025 -23.99 Mn
Sep 30, 2025 73.79 Mn
Jun 30, 2025 70.45 Mn
Mar 31, 2025 56.31 Mn
Dec 31, 2024 47.06 Mn
Sep 30, 2024 45.84 Mn
Jun 30, 2024 33.32 Mn
Mar 31, 2024 32.02 Mn
Dec 31, 2023 30.99 Mn
Sep 30, 2023 26.15 Mn
Jun 30, 2023 25.99 Mn
Mar 31, 2023 19.65 Mn
Dec 31, 2022 12.96 Mn
Sep 30, 2022 12.69 Mn
Jun 30, 2022 13.96 Mn
Mar 31, 2022 12.95 Mn