Cyclerion Therapeutics CYCN
NASDAQ CYCN
$3.36 -0.85 (-20.19%)
At close: Sep 8, 2026 · 4:00 PM EDT

Cyclerion Therapeutics (CYCN) Price to Earnings (2019 - 2025)

Cyclerion Therapeutics (CYCN) posted Price to Earnings of 8.45 for Q3 2025, down 57.81% on a QoQ basis from 5.35 in Q2 2025, and down 45.38% year-over-year from 15.47 in Q3 2024.

Analysis

Cyclerion Therapeutics (CYCN) Price to Earnings (2019 - 2025) Analysis & Trends

Cyclerion Therapeutics has reported Price to Earnings for 7 years, with the latest figure at 8.45 in Q3 2025.

  • On a quarterly basis, Price to Earnings fell 45.38% year-over-year to 8.45 in Q3 2025; TTM through Sep 2025 was 2.34, a 111.45% decrease from a year earlier, with the FY2024 full-year figure at 2.26, down 53.24% from the prior year.
  • Price to Earnings was 8.45 for Q3 2025 at Cyclerion Therapeutics, down from 5.35 in the prior quarter.
  • The five-year high for Price to Earnings was 16.33 in Q4 2024, with the low at 11.78 in Q3 2021.
  • Average Price to Earnings over 5 years is 3.78, with a median of 4.62 recorded in 2023.
  • The sharpest annual moves came in 2021 and 2024: Price to Earnings tumbled 196078.61% in 2021, then soared 453.66% in 2024.
  • Over 5 years, Price to Earnings stood at 5.21 in 2021, then advanced by 25.37% to 3.89 in 2022, then dropped by 18.81% to 4.62 in 2023, then soared by 453.66% to 16.33 in 2024, then sank by 151.73% to 8.45 in 2025.
  • The last three Price to Earnings figures came in at 8.45 (Q3 2025), 5.35 (Q2 2025), and 5.25 (Q1 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Amgen 206.67 Bn 192.69 Bn 7.24 Bn
2 Gilead Sciences 180.06 Bn 176.88 Bn 6.22 Bn
3 Vertex Pharmaceuticals 131.44 Bn 123.59 Bn 2.84 Bn
4 Regeneron Pharmaceuticals 81.94 Bn 73.95 Bn 3.93 Bn
5 Argenx Se 60.28 Bn 55.10 Bn 1.37 Bn
6 Moderna 53.87 Bn 48.73 Bn 52.00 Mn
7 Alnylam Pharmaceuticals 33.15 Bn 29.85 Bn 992.69 Mn
8 Biogen 31.88 Bn 30.60 Bn 1.96 Bn
9 Roivant Sciences 29.16 Bn 29.16 Bn 1.16 Mn
10 Cyclerion Therapeutics 15.70 Mn 12.46 Mn -
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2025 -8.45
Jun 30, 2025 -5.35
Mar 31, 2025 -5.25
Dec 31, 2024 16.33
Sep 30, 2024 -5.81
Jun 30, 2024 -4.18
Mar 31, 2024 -4.94
Dec 31, 2023 -4.62
Sep 30, 2023 1.12
Jun 30, 2023 -2.34
Mar 31, 2023 -2.68
Dec 31, 2022 -3.89
Sep 30, 2022 -3.53
Jun 30, 2022 -1.78
Mar 31, 2022 -3.71
Dec 31, 2021 -5.21
Sep 30, 2021 -11.78
Jun 30, 2021 -8.61
Mar 31, 2021 -7.11
Dec 31, 2020 -5.42