Biofrontera (BFRI) Operating Margin (2020 - 2026)
Biofrontera (BFRI) posted Operating Margin of -4.37% for Q2 2026, up 51.88 percentage points from -56.25% a year earlier.
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Analysis
Biofrontera (BFRI) Operating Margin (2020 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Operating Margin at Biofrontera was -16.23%, up 25.36 percentage points year-over-year; for FY2025, it came in at -27.21%, up 18.90 percentage points from FY2024.
- Annual Operating Margin shows a five-year change of +23.75 percentage points (FY2020 to FY2025).
- In prior years, Biofrontera's Operating Margin was -46.11% in FY2024 (+20.44 pp), -66.56% in FY2023 (-1.76 pp), -64.80% in FY2022 (+39.77 pp) and -104.57% in FY2021 (-53.61 pp).
- Quarterly Operating Margin has run from a low of -371.60% in Q3 2021 to a high of 26.66% in Q4 2025 over five years.
- On a year-over-year basis, Operating Margin increased in five of the last seven quarters, with an average year-over-year change of +14.53 percentage points.
- The strongest year-over-year quarter for Operating Margin in the past five years was Q3 2022, with a gain of 287.40 percentage points; the weakest was Q3 2021, with a drop of 299.52 percentage points.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Biofrontera | 15.48 Mn | -6.31 Mn | 9.59 Mn | -4.37% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -4.37% |
| Dec 31, 2025 | 26.66% |
| Sep 30, 2025 | -89.84% |
| Jun 30, 2025 | -56.25% |
| Mar 31, 2025 | -52.95% |
| Dec 31, 2024 | -13.63% |
| Sep 30, 2024 | -55.04% |
| Jun 30, 2024 | -64.69% |
| Mar 31, 2024 | -69.10% |
| Dec 31, 2023 | -36.48% |
| Sep 30, 2023 | -51.93% |
| Jun 30, 2023 | -148.75% |
| Mar 31, 2023 | -62.89% |
| Dec 31, 2022 | -55.02% |
| Sep 30, 2022 | -84.20% |
| Jun 30, 2022 | -139.38% |
| Mar 31, 2022 | -31.89% |
| Dec 31, 2021 | -20.51% |
| Sep 30, 2021 | -371.60% |
| Jun 30, 2021 | -62.97% |
API Access
Biofrontera Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=BFRI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "BFRI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=BFRI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();