Assembly Biosciences (ASMB) Operating Margin (2017 - 2026)
Assembly Biosciences' Operating Margin was -47.44% in Q2 2026, up 67.80 percentage points from -115.24% a year earlier and up 91.00 percentage points from the prior quarter.
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Analysis
Assembly Biosciences (ASMB) Operating Margin (2017 - 2026) Analysis & Trends
On a trailing twelve-month basis, Assembly Biosciences' Operating Margin was -11.75% through Jun 30, 2026, up 119.15 percentage points year-over-year; for FY2025, it came in at -16.76%, up 142.50 percentage points from FY2024.
- Operating Margin shows a five-year change of +65.13 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was -159.26% in FY2024 (+743.24 pp), -902.50% in FY2023 and -2121.65% in FY2021 (-2039.76 pp).
- Quarterly Operating Margin has moved between -301.81% (Q3 2021) and 46.62% (Q4 2025) over five years.
- Compared with a year earlier, Operating Margin was higher in six of the last seven quarters, with an average year-over-year change of +60.52 percentage points.
- The best year-over-year quarter for Operating Margin over five years was Q4 2025 (a gain of 203.37 percentage points); the worst was Q3 2021 (a drop of 290.19 percentage points).
- Per Business Quant data, ASMB's Operating Margin in the three quarters before Q2 2026 was -138.44% (Q1 2026), 46.62% (Q4 2025) and -100.87% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Assembly Biosciences | 468.67 Mn | -558.96 Mn | - | -47.44% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -47.44% |
| Mar 31, 2026 | -138.44% |
| Dec 31, 2025 | 46.62% |
| Sep 30, 2025 | -100.87% |
| Jun 30, 2025 | -115.24% |
| Mar 31, 2025 | -105.54% |
| Dec 31, 2024 | -156.75% |
| Sep 30, 2024 | -160.06% |
| Jun 30, 2024 | -143.01% |
| Mar 31, 2024 | -185.46% |
| Dec 31, 2023 | -175.22% |
| Sep 30, 2021 | -301.81% |
| Dec 31, 2020 | -3,822.76% |
| Sep 30, 2020 | -11.61% |
| Jun 30, 2020 | 16.71% |
| Mar 31, 2020 | -678.61% |
| Dec 31, 2019 | -601.72% |
| Sep 30, 2019 | -614.35% |
| Jun 30, 2019 | -639.61% |
| Mar 31, 2019 | -729.37% |
API Access
Assembly Biosciences Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ASMB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ASMB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ASMB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();