Growth Metrics

Apellis Pharmaceuticals (APLS) Net Margin (2020 - 2025)

Apellis Pharmaceuticals filings provide 6 years of Net Margin readings, the most recent being 29.49% for Q4 2025.

  • For the quarter ending Q4 2025, Net Margin fell 9426.0% year-over-year to 29.49%, compared with a TTM value of 2.23% through Dec 2025, up 528.0%, and an annual FY2025 reading of 2.23%, up 528.0% over the prior year.
  • Net Margin hit 29.49% in Q4 2025 for Apellis Pharmaceuticals, down from 47.04% in the prior quarter.
  • The five-year high for Net Margin was 470.05% in Q4 2021, with the low at 35183.15% in Q2 2021.
  • Median Net Margin over the past 5 years was 55.29% (2025), compared with a mean of 2215.42%.
  • The largest YoY upside for Net Margin was 3422752bps in 2022 against a maximum downside of -83707bps in 2022.
  • Year by year, Net Margin stood at 470.05% in 2021, then tumbled by -178bps to 367.01% in 2022, then surged by 93bps to 27.39% in 2023, then skyrocketed by 337bps to 64.77% in 2024, then plummeted by -146bps to 29.49% in 2025.
  • According to Business Quant data, Net Margin over the past three periods came in at 29.49%, 47.04%, and 23.63% for Q4 2025, Q3 2025, and Q2 2025 respectively.