Growth Metrics

Apellis Pharmaceuticals (APLS) Gross Margin (2021 - 2025)

Apellis Pharmaceuticals filings provide 5 years of Gross Margin readings, the most recent being 85.13% for Q4 2025.

  • For the quarter ending Q4 2025, Gross Margin rose 436.0% year-over-year to 85.13%, compared with a TTM value of 89.81% through Dec 2025, up 488.0%, and an annual FY2025 reading of 89.81%, up 488.0% over the prior year.
  • Gross Margin hit 85.13% in Q4 2025 for Apellis Pharmaceuticals, down from 94.65% in the prior quarter.
  • The five-year high for Gross Margin was 99.92% in Q4 2021, with the low at 79.4% in Q1 2025.
  • Median Gross Margin over the past 5 years was 88.35% (2024), compared with a mean of 88.93%.
  • The sharpest move saw Gross Margin tumbled -1404bps in 2023, then soared 1170bps in 2025.
  • Year by year, Gross Margin stood at 99.92% in 2021, then decreased by -13bps to 87.09% in 2022, then dropped by -1bps to 86.4% in 2023, then decreased by -7bps to 80.78% in 2024, then grew by 5bps to 85.13% in 2025.
  • According to Business Quant data, Gross Margin over the past three periods came in at 85.13%, 94.65%, and 92.37% for Q4 2025, Q3 2025, and Q2 2025 respectively.