Growth Metrics

Apellis Pharmaceuticals (APLS) Gross Margin (2021 - 2025)

Apellis Pharmaceuticals has reported Gross Margin over the past 5 years, most recently at 85.13% for Q4 2025.

  • Quarterly results put Gross Margin at 85.13% for Q4 2025, up 436.0% from a year ago — trailing twelve months through Dec 2025 was 89.81% (up 488.0% YoY), and the annual figure for FY2025 was 89.81%, up 488.0%.
  • Gross Margin for Q4 2025 was 85.13% at Apellis Pharmaceuticals, down from 94.65% in the prior quarter.
  • Over the last five years, Gross Margin for APLS hit a ceiling of 99.92% in Q4 2021 and a floor of 79.4% in Q1 2025.
  • Median Gross Margin over the past 5 years was 88.35% (2024), compared with a mean of 88.93%.
  • Biggest five-year swings in Gross Margin: crashed -1404bps in 2023 and later skyrocketed 1170bps in 2025.
  • Apellis Pharmaceuticals' Gross Margin stood at 99.92% in 2021, then dropped by -13bps to 87.09% in 2022, then fell by -1bps to 86.4% in 2023, then dropped by -7bps to 80.78% in 2024, then rose by 5bps to 85.13% in 2025.
  • The last three reported values for Gross Margin were 85.13% (Q4 2025), 94.65% (Q3 2025), and 92.37% (Q2 2025) per Business Quant data.