Growth Metrics

Apellis Pharmaceuticals (APLS) EBITDA Margin (2020 - 2025)

Apellis Pharmaceuticals has reported EBITDA Margin over the past 6 years, most recently at 29.34% for Q4 2025.

  • Quarterly results put EBITDA Margin at 29.34% for Q4 2025, down 1216.0% from a year ago — trailing twelve months through Dec 2025 was 2.35% (up 2765.0% YoY), and the annual figure for FY2025 was 2.35%, up 2765.0%.
  • EBITDA Margin for Q4 2025 was 29.34% at Apellis Pharmaceuticals, down from 47.08% in the prior quarter.
  • Over the last five years, EBITDA Margin for APLS hit a ceiling of 47.08% in Q3 2025 and a floor of 35216.69% in Q2 2021.
  • Median EBITDA Margin over the past 5 years was 127.27% (2023), compared with a mean of 2280.17%.
  • Peak annual rise in EBITDA Margin hit 3425412bps in 2022, while the deepest fall reached -47743bps in 2022.
  • Apellis Pharmaceuticals' EBITDA Margin stood at 245.5% in 2021, then tumbled by -194bps to 722.94% in 2022, then surged by 91bps to 62.2% in 2023, then skyrocketed by 72bps to 17.18% in 2024, then plummeted by -71bps to 29.34% in 2025.
  • The last three reported values for EBITDA Margin were 29.34% (Q4 2025), 47.08% (Q3 2025), and 23.34% (Q2 2025) per Business Quant data.