Amylyx Pharmaceuticals (AMLX) Operating Expenses (2021 - 2026)
Amylyx Pharmaceuticals' (AMLX) quarterly Operating Expenses came in at $43.8 million in Q1 2026, up 15.81% year-on-year from $37.8 million in Q1 2025, and up 19.6% quarter-over-quarter from $36.6 million in Q4 2025.
Amylyx Pharmaceuticals (AMLX) Operating Expenses (2021 - 2026) Analysis & Trends
Amylyx Pharmaceuticals' Operating Expenses history runs 6 years deep, the most recent figure standing at $43.8 million for Q1 2026.
- On a quarterly basis, Operating Expenses rose 15.81% year-over-year to $43.8 million in Q1 2026; TTM through Mar 2026 was $159.3 million, a 30.49% decrease from a year earlier, with the FY2025 full-year figure at $153.3 million, down 61.88% from the prior year.
- Operating Expenses improved to $43.8 million in Q1 2026 per AMLX's latest filing, from $36.6 million in the prior quarter.
- Across five years, Operating Expenses topped out at $210.8 million in Q1 2024 and bottomed at $36.0 million in Q3 2025.
- The 5-year median for Operating Expenses is $55.0 million (2022), against an average of $68.5 million.
- Across the five-year window, Operating Expenses soared 271.57% in 2022 and sank 82.06% in 2025, its largest moves.
- Year by year, Operating Expenses stood at $66.5 million in 2022, then jumped by 60.23% to $106.5 million in 2023, then plunged by 62.46% to $40.0 million in 2024, then decreased by 8.46% to $36.6 million in 2025, then grew by 19.6% to $43.8 million in 2026.
- Per Business Quant, the three latest AMLX Operating Expenses figures stand at $43.8 million (Q1 2026), $36.6 million (Q4 2025), and $36.0 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Haleon | 87.22 Bn | 85.35 Bn | - | - |
| 2 | Teva Pharmaceutical Industries | 39.60 Bn | 35.87 Bn | 1.97 Bn | 1.00 Bn |
| 3 | Zoetis | 31.46 Bn | 29.52 Bn | 1.62 Bn | 788.00 Mn |
| 4 | Takeda Pharmaceutical | 26.49 Bn | 22.44 Bn | 4.39 Bn | 12.58 Bn |
| 5 | United Therapeutics | 23.03 Bn | 20.88 Bn | 648.10 Mn | 455.70 Mn |
| 6 | Universe Pharmaceuticals | 23.03 Bn | -10.56 Bn | - | - |
| 7 | Viatris | 20.90 Bn | 19.09 Bn | 1.16 Bn | 1.24 Bn |
| 8 | Neurocrine Biosciences | 17.50 Bn | 16.19 Bn | 800.70 Mn | 621.10 Mn |
| 9 | Elanco Animal Health | 12.33 Bn | 11.91 Bn | 785.00 Mn | 494.00 Mn |
| 10 | Amylyx Pharmaceuticals | 1.94 Bn | 1.94 Bn | - | 43.78 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 43.78 Mn |
| Dec 31, 2025 | 36.61 Mn |
| Sep 30, 2025 | 36.03 Mn |
| Jun 30, 2025 | 42.86 Mn |
| Mar 31, 2025 | 37.80 Mn |
| Dec 31, 2024 | 39.99 Mn |
| Sep 30, 2024 | 76.08 Mn |
| Jun 30, 2024 | 75.26 Mn |
| Mar 31, 2024 | 210.77 Mn |
| Dec 31, 2023 | 106.52 Mn |
| Sep 30, 2023 | 83.97 Mn |
| Jun 30, 2023 | 78.02 Mn |
| Mar 31, 2023 | 73.48 Mn |
| Dec 31, 2022 | 66.48 Mn |
| Sep 30, 2022 | 55.03 Mn |
| Jun 30, 2022 | 54.25 Mn |
| Mar 31, 2022 | 47.81 Mn |
| Dec 31, 2021 | 28.32 Mn |
| Sep 30, 2021 | 23.20 Mn |
| Jun 30, 2021 | 18.59 Mn |