Amylyx Pharmaceuticals (AMLX) Operating Expenses (2021 - 2026)
Amylyx Pharmaceuticals (AMLX) reported Operating Expenses of $45.69 million for Q2 2026, up 6.6% from $42.86 million a year earlier and up 4.4% from the prior quarter.
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Analysis
Amylyx Pharmaceuticals (AMLX) Operating Expenses (2021 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Amylyx Pharmaceuticals' Operating Expenses came in at $162.1 million, down 17.6% year-over-year; for FY2025, it was $153.29 million, down 61.9% from FY2024.
- Operating Expenses has a four-year compound annual growth rate of 16.6% (FY2021 to FY2025).
- By year, Operating Expenses came in at $402.1 million in FY2024 (+17.6%), $341.98 million in FY2023 (+53.0%), $223.57 million in FY2022 (+169.5%) and $82.97 million in FY2021.
- The Q2 2026 figure ranks as the highest quarterly Operating Expenses since Q3 2024.
- Year over year, Operating Expenses gained in two of the last eight quarters, with an average decline of 29.5%.
- The high point for year-over-year Operating Expenses in five years was Q1 2022 (growth of 271.6%); the low point was Q1 2025 (a decline of 82.1%).
- Per Business Quant data, the three quarters before Q2 2026 came in at $43.78 million (Q1 2026), $36.61 million (Q4 2025) and $36.03 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 10.12 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 10.56 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 12.80 Bn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | -6.09 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | -9.70 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 6.54 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 18.20 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 6.68 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 2.09 Bn |
| 10 | Amylyx Pharmaceuticals | 3.32 Bn | 3.32 Bn | - | 45.69 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 45.69 Mn |
| Mar 31, 2026 | 43.78 Mn |
| Dec 31, 2025 | 36.61 Mn |
| Sep 30, 2025 | 36.03 Mn |
| Jun 30, 2025 | 42.86 Mn |
| Mar 31, 2025 | 37.80 Mn |
| Dec 31, 2024 | 39.99 Mn |
| Sep 30, 2024 | 76.08 Mn |
| Jun 30, 2024 | 75.26 Mn |
| Mar 31, 2024 | 210.77 Mn |
| Dec 31, 2023 | 106.52 Mn |
| Sep 30, 2023 | 83.97 Mn |
| Jun 30, 2023 | 78.02 Mn |
| Mar 31, 2023 | 73.48 Mn |
| Dec 31, 2022 | 66.48 Mn |
| Sep 30, 2022 | 55.03 Mn |
| Jun 30, 2022 | 54.25 Mn |
| Mar 31, 2022 | 47.81 Mn |
| Dec 31, 2021 | 28.32 Mn |
| Sep 30, 2021 | 23.20 Mn |
API Access
Amylyx Pharmaceuticals Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-expenses&ticker=AMLX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-expenses", "ticker": "AMLX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-expenses&ticker=AMLX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();