Amylyx Pharmaceuticals (AMLX) Operating Expenses (2021 - 2026)
Amylyx Pharmaceuticals (AMLX) posted Operating Expenses of $45.7 million for Q2 2026, up 4.37% on a QoQ basis from $43.8 million in Q1 2026, and up 6.62% year-over-year from $42.9 million in Q2 2025.
Analysis
Amylyx Pharmaceuticals (AMLX) Operating Expenses (2021 - 2026) Analysis & Trends
Amylyx Pharmaceuticals has reported Operating Expenses for 6 years, with the latest figure at $45.7 million in Q2 2026.
- On a quarterly basis, Operating Expenses rose 6.62% year-over-year to $45.7 million in Q2 2026; TTM through Jun 2026 was $162.1 million, a 17.6% decrease from a year earlier, with the FY2025 full-year figure at $153.3 million, down 61.88% from the prior year.
- Operating Expenses was $45.7 million for Q2 2026 at Amylyx Pharmaceuticals, up from $43.8 million in the prior quarter.
- The five-year high for Operating Expenses was $210.8 million in Q1 2024, with the low at $36.0 million in Q3 2025.
- Average Operating Expenses over 5 years is $67.2 million, with a median of $54.6 million recorded in 2022.
- The sharpest annual moves came in 2022 and 2025: Operating Expenses surged 271.57% in 2022, then plunged 82.06% in 2025.
- Over 5 years, Operating Expenses stood at $66.5 million in 2022, then surged by 60.23% to $106.5 million in 2023, then sank by 62.46% to $40.0 million in 2024, then slipped by 8.46% to $36.6 million in 2025, then grew by 24.83% to $45.7 million in 2026.
- The last three Operating Expenses figures came in at $45.7 million (Q2 2026), $43.8 million (Q1 2026), and $36.6 million (Q4 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 212.20 Bn | 198.21 Bn | 7.24 Bn | 6.54 Bn |
| 2 | Gilead Sciences | 181.83 Bn | 178.65 Bn | 6.22 Bn | 18.20 Bn |
| 3 | Vertex Pharmaceuticals | 132.47 Bn | 124.61 Bn | 2.84 Bn | 2.09 Bn |
| 4 | Regeneron Pharmaceuticals | 82.56 Bn | 74.56 Bn | 3.93 Bn | 3.00 Bn |
| 5 | Argenx Se | 61.59 Bn | 56.40 Bn | 1.37 Bn | -1.05 Bn |
| 6 | Moderna | 54.65 Bn | 49.51 Bn | 52.00 Mn | 960.00 Mn |
| 7 | Alnylam Pharmaceuticals | 34.13 Bn | 30.82 Bn | 992.69 Mn | 1.06 Bn |
| 8 | Biogen | 31.42 Bn | 30.13 Bn | 1.96 Bn | 2.60 Bn |
| 9 | Roivant Sciences | 30.21 Bn | 30.21 Bn | 1.16 Mn | 367.83 Mn |
| 10 | Amylyx Pharmaceuticals | 3.68 Bn | 3.68 Bn | - | 45.69 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 45.69 Mn |
| Mar 31, 2026 | 43.78 Mn |
| Dec 31, 2025 | 36.61 Mn |
| Sep 30, 2025 | 36.03 Mn |
| Jun 30, 2025 | 42.86 Mn |
| Mar 31, 2025 | 37.80 Mn |
| Dec 31, 2024 | 39.99 Mn |
| Sep 30, 2024 | 76.08 Mn |
| Jun 30, 2024 | 75.26 Mn |
| Mar 31, 2024 | 210.77 Mn |
| Dec 31, 2023 | 106.52 Mn |
| Sep 30, 2023 | 83.97 Mn |
| Jun 30, 2023 | 78.02 Mn |
| Mar 31, 2023 | 73.48 Mn |
| Dec 31, 2022 | 66.48 Mn |
| Sep 30, 2022 | 55.03 Mn |
| Jun 30, 2022 | 54.25 Mn |
| Mar 31, 2022 | 47.81 Mn |
| Dec 31, 2021 | 28.32 Mn |
| Sep 30, 2021 | 23.20 Mn |