Alnylam Pharmaceuticals (ALNY) Operating Expenses (2009 - 2026)

Alnylam Pharmaceuticals' (ALNY) quarterly Operating Expenses came in at $1.1 billion in Q2 2026, up 34.13% YoY from $789.9 million in Q2 2025, and up 17.91% on a QoQ basis from $898.5 million in Q1 2026.

Alnylam Pharmaceuticals (ALNY) Operating Expenses (2009 - 2026) Analysis & Trends

Alnylam Pharmaceuticals (ALNY) has 18 years of Operating Expenses data on file, last reported at $1.1 billion in Q2 2026.

  • Quarterly Operating Expenses rose 34.13% year-over-year to $1.1 billion in Q2 2026, while the trailing twelve-month figure through Jun 2026 was $3.8 billion (up 43.99% YoY) and the FY2025 annual result came in at $3.2 billion, up 32.46% from the prior year.
  • Operating Expenses grew to $1.1 billion in Q2 2026, from $898.5 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $1.1 billion in Q2 2026 to a low of $360.0 million in Q1 2022.
  • A 5-year average of $640.5 million and a median of $566.1 million in 2023 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2022 — Operating Expenses dropped 1.05% — and 2026, when it surged 55.97%.
  • Tracing ALNY's Operating Expenses over 5 years: stood at $523.6 million in 2022, then grew by 6.2% to $556.1 million in 2023, then rose by 25.57% to $698.3 million in 2024, then jumped by 38.23% to $965.3 million in 2025, then climbed by 9.76% to $1.1 billion in 2026.
  • The last three Operating Expenses figures came in at $1.1 billion (Q2 2026), $898.5 million (Q1 2026), and $965.3 million (Q4 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 2.89 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.21 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 4,978.15
7 Royalty Pharma 33.72 Bn 35.84 Bn - 541.02 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.06 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 427.03 Mn
10 Roivant Sciences 26.16 Bn 26.85 Bn 1.16 Mn 367.83 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 1.06 Bn
Mar 31, 2026 898.54 Mn
Dec 31, 2025 965.32 Mn
Sep 30, 2025 881.04 Mn
Jun 30, 2025 789.89 Mn
Mar 31, 2025 576.11 Mn
Dec 31, 2024 698.33 Mn
Sep 30, 2024 577.82 Mn
Jun 30, 2024 611.21 Mn
Mar 31, 2024 537.77 Mn
Dec 31, 2023 556.12 Mn
Sep 30, 2023 536.66 Mn
Jun 30, 2023 548.59 Mn
Mar 31, 2023 469.10 Mn
Dec 31, 2022 523.65 Mn
Sep 30, 2022 522.35 Mn
Jun 30, 2022 416.50 Mn
Mar 31, 2022 359.99 Mn
Dec 31, 2021 453.10 Mn
Sep 30, 2021 369.31 Mn