Alnylam Pharmaceuticals (ALNY) Operating Expenses (2009 - 2026)
Alnylam Pharmaceuticals (ALNY) reported Operating Expenses of $898.5 million for Q1 2026, up 55.97% on a YoY basis from $576.1 million in Q1 2025, and down 6.92% quarter-over-quarter from $965.3 million in Q4 2025.
Alnylam Pharmaceuticals (ALNY) Operating Expenses (2009 - 2026) Analysis & Trends
Alnylam Pharmaceuticals has reported Operating Expenses for 18 years, with the latest figure at $898.5 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Expenses rose 55.97% year-over-year to $898.5 million; the trailing twelve-month figure through Mar 2026 stood at $3.5 billion (up 43.49% YoY), and the FY2025 full-year result was $3.2 billion, up 32.46% from the prior year.
- Operating Expenses for Q1 2026 stood at $898.5 million, down from $965.3 million in the prior quarter.
- The five-year high for Operating Expenses was $965.3 million in Q4 2025, with the low at $360.0 million in Q1 2022.
- Historically, Operating Expenses has averaged $615.8 million across 5 years, with a median of $556.1 million in 2023.
- Annual changes were most pronounced in 2022 — Operating Expenses dropped 1.05% — and 2026, when it surged 55.97%.
- Alnylam Pharmaceuticals' Operating Expenses stood at $523.6 million in 2022, then grew by 6.2% to $556.1 million in 2023, then rose by 25.57% to $698.3 million in 2024, then jumped by 38.23% to $965.3 million in 2025, then decreased by 6.92% to $898.5 million in 2026.
- The last three Operating Expenses figures came in at $898.5 million (Q1 2026), $965.3 million (Q4 2025), and $881.0 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | Alnylam Pharmaceuticals | 37.04 Bn | 34.03 Bn | 959.66 Mn | 898.54 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 898.54 Mn |
| Dec 31, 2025 | 965.32 Mn |
| Sep 30, 2025 | 881.04 Mn |
| Jun 30, 2025 | 789.89 Mn |
| Mar 31, 2025 | 576.11 Mn |
| Dec 31, 2024 | 698.33 Mn |
| Sep 30, 2024 | 577.82 Mn |
| Jun 30, 2024 | 611.21 Mn |
| Mar 31, 2024 | 537.77 Mn |
| Dec 31, 2023 | 556.12 Mn |
| Sep 30, 2023 | 536.66 Mn |
| Jun 30, 2023 | 548.59 Mn |
| Mar 31, 2023 | 469.10 Mn |
| Dec 31, 2022 | 523.65 Mn |
| Sep 30, 2022 | 522.35 Mn |
| Jun 30, 2022 | 416.50 Mn |
| Mar 31, 2022 | 359.99 Mn |
| Dec 31, 2021 | 453.10 Mn |
| Sep 30, 2021 | 369.31 Mn |
| Jun 30, 2021 | 366.71 Mn |