Alnylam Pharmaceuticals (ALNY) Operating Expenses (2009 - 2026)
Alnylam Pharmaceuticals (ALNY) posted Operating Expenses of $898.5 million for Q1 2026, down 6.92% on a QoQ basis from $965.3 million in Q4 2025, and up 55.97% year-over-year from $576.1 million in Q1 2025.
Alnylam Pharmaceuticals (ALNY) Operating Expenses (2009 - 2026) Analysis & Trends
Alnylam Pharmaceuticals' Operating Expenses history runs 18 years deep, the most recent figure standing at $898.5 million for Q1 2026.
- Quarterly Operating Expenses rose 55.97% year-over-year to $898.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $3.5 billion (up 43.49% YoY) and the FY2025 annual result came in at $3.2 billion, up 32.46% from the prior year.
- Operating Expenses was $898.5 million for Q1 2026 at Alnylam Pharmaceuticals, down from $965.3 million in the prior quarter.
- Across five years, Operating Expenses topped out at $965.3 million in Q4 2025 and bottomed at $360.0 million in Q1 2022.
- A 5-year average of $615.8 million and a median of $556.1 million in 2023 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2022 — Operating Expenses retreated 1.05% — and 2026, when it surged 55.97%.
- Alnylam Pharmaceuticals' Operating Expenses stood at $523.6 million in 2022, then rose by 6.2% to $556.1 million in 2023, then advanced by 25.57% to $698.3 million in 2024, then soared by 38.23% to $965.3 million in 2025, then dropped by 6.92% to $898.5 million in 2026.
- Business Quant data shows ALNY's Operating Expenses at $898.5 million in Q1 2026, $965.3 million in Q4 2025, and $881.0 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | Alnylam Pharmaceuticals | 36.08 Bn | 33.07 Bn | 959.66 Mn | 898.54 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 898.54 Mn |
| Dec 31, 2025 | 965.32 Mn |
| Sep 30, 2025 | 881.04 Mn |
| Jun 30, 2025 | 789.89 Mn |
| Mar 31, 2025 | 576.11 Mn |
| Dec 31, 2024 | 698.33 Mn |
| Sep 30, 2024 | 577.82 Mn |
| Jun 30, 2024 | 611.21 Mn |
| Mar 31, 2024 | 537.77 Mn |
| Dec 31, 2023 | 556.12 Mn |
| Sep 30, 2023 | 536.66 Mn |
| Jun 30, 2023 | 548.59 Mn |
| Mar 31, 2023 | 469.10 Mn |
| Dec 31, 2022 | 523.65 Mn |
| Sep 30, 2022 | 522.35 Mn |
| Jun 30, 2022 | 416.50 Mn |
| Mar 31, 2022 | 359.99 Mn |
| Dec 31, 2021 | 453.10 Mn |
| Sep 30, 2021 | 369.31 Mn |
| Jun 30, 2021 | 366.71 Mn |