Over the trailing 12 months, ALNY insiders sold $40.29 million worth of shares (108.43K shares) in open-market trades, with no open-market purchases.
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Yvonne Greenstreet | Chief Executive Officer | 95,802 | 0 | 95,802 | 28.0% | 22 Sep, 2026 |
| 2 | Jeffrey V. Poulton | Evp, Chief Financial Officer | 61,805 | 0 | 61,805 | 18.1% | 06 Mar, 2026 |
| 3 | Tolga Tanguler | Evp, Chief Commercial Officer | 34,297 | 0 | 34,297 | 10.0% | 06 Mar, 2026 |
| 4 | Amy W Schulman | Director | 24,049 | 0 | 24,049 | 7.0% | 22 May, 2026 |
| 5 | Akshay Vaishnaw | President | 22,774 | 0 | 22,774 | 6.7% | 07 Aug, 2023 |
| 6 | Kevin Joseph Fitzgerald | Cso Evp, Head Of Research | 20,569 | 0 | 20,569 | 6.0% | 06 Mar, 2026 |
| 7 | Pushkal Garg | Evp Chief Rd | 18,693 | 0 | 18,693 | 5.5% | 06 Mar, 2026 |
| 8 | Michael W Bonney | Director | 16,804 | 0 | 16,804 | 4.9% | 19 Aug, 2025 |
| 9 | Bryan Supran | Evp, Clo And Secretary | 12,807 | 0 | 12,807 | 3.7% | 06 Oct, 2026 |
| 10 | Melissa Mclaughlin | Chief Human Resources Officer | 9,443 | 0 | 9,443 | 2.8% | 07 Apr, 2026 |
| 11 | Robert W. Hesslein | Evp, Clo And Secretary | 8,002 | 0 | 8,002 | 2.3% | 05 Mar, 2025 |
| 12 | Indrani Lall Franchini | Evp, Clo Secretary | 4,133 | 0 | 4,133 | 1.2% | 29 Feb, 2024 |
| 13 | David E I Pyott | Director | 1,582 | 0 | 1,582 | 0.5% | 03 Jun, 2026 |
| 14 | Dennis A Ausiello | Director | 1,582 | 0 | 1,582 | 0.5% | 22 May, 2026 |
| 15 | Margaret A Hamburg | Director | 1,582 | 0 | 1,582 | 0.5% | 22 May, 2026 |
| 16 | Charles Elliott Sigal | Director | 1,446 | 0 | 1,446 | 0.4% | 22 May, 2026 |
| 17 | Colleen F Reitan | Director | 1,446 | 0 | 1,446 | 0.4% | 22 May, 2026 |
| 18 | Olivier Brandicourt | Director | 1,446 | 0 | 1,446 | 0.4% | 22 May, 2026 |
| 19 | Peter N Kellogg | Director | 1,446 | 0 | 1,446 | 0.4% | 22 May, 2026 |
| 20 | Steven M Paul | Director | 1,000 | 0 | 1,000 | 0.3% | 05 Apr, 2022 |
| 21 | Carolyn R Bertozzi | Director | 775 | 0 | 775 | 0.2% | 12 May, 2025 |
| 22 | Stuart A Arbuckle | Director | 671 | 0 | 671 | 0.2% | 22 May, 2026 |
| 23 | Marsha Fanucci | Director | 136 | 0 | 136 | 0.0% | 27 Feb, 2023 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 02 Oct, 2026 | Bryan Supran | Evp, Clo And Secretary | Disposed S | 1,758 | $226.88 | $398.86K | 12,807 | Direct |
| 19 Sep, 2026 | Yvonne Greenstreet | Chief Executive Officer | Acquired A | 107 | $0.00 | $0 | 95,802 | Direct |
| 01 Jun, 2026 | David E I Pyott | Director | Acquired M | 3,830 | $0.00 | $0 | 5,412 | Direct |
| 01 Jun, 2026 | Benjamin Cravatt | Director | Acquired A | 4,393 | $0.00 | $0 | 4,393 | Direct |
| 01 Jun, 2026 | David E I Pyott | Director | Disposed S | 921 | $297.71 | $274.19K | 4,491 | Direct |
| 01 Jun, 2026 | David E I Pyott | Director | Disposed S | 1,175 | $298.91 | $351.22K | 3,316 | Direct |
| 01 Jun, 2026 | David E I Pyott | Director | Disposed S | 1,222 | $299.87 | $366.44K | 2,094 | Direct |
| 01 Jun, 2026 | David E I Pyott | Director | Disposed S | 495 | $300.72 | $148.86K | 1,599 | Direct |
| 01 Jun, 2026 | David E I Pyott | Director | Disposed S | 17 | $302.65 | $5.15K | 1,582 | Direct |
| 01 Jun, 2026 | David E I Pyott | Director | Disposed M | 3,830 | $0.00 | $0 | 0 | Direct |
| 20 May, 2026 | Margaret A Hamburg | Director | Acquired A | 671 | $0.00 | $0 | 1,582 | Direct |
| 20 May, 2026 | David E I Pyott | Director | Acquired A | 671 | $0.00 | $0 | 1,582 | Direct |
| 20 May, 2026 | Colleen F Reitan | Director | Acquired A | 671 | $0.00 | $0 | 1,446 | Direct |
| 20 May, 2026 | Stuart A Arbuckle | Director | Acquired A | 671 | $0.00 | $0 | 671 | Direct |
| 20 May, 2026 | Amy W Schulman | Director | Acquired A | 838 | $0.00 | $0 | 24,049 | Direct |
| 20 May, 2026 | Peter N Kellogg | Director | Acquired A | 671 | $0.00 | $0 | 1,446 | Direct |
| 20 May, 2026 | Charles Elliott Sigal | Director | Acquired A | 671 | $0.00 | $0 | 1,446 | Direct |
| 20 May, 2026 | Dennis A Ausiello | Director | Acquired A | 671 | $0.00 | $0 | 1,582 | Direct |
| 20 May, 2026 | Olivier Brandicourt | Director | Acquired A | 671 | $0.00 | $0 | 1,446 | Direct |
| 20 May, 2026 | Stuart A Arbuckle | Director | Acquired A | 1,441 | $0.00 | $0 | 1,441 | Direct |