Alumis (ALMS) Operating Expenses (2023 - 2025)

Alumis' (ALMS) quarterly Operating Expenses came in at $98.4 million in Q4 2025, little changed year-on-year from $98.6 million in Q4 2024, and down 16.18% on a QoQ basis from $117.4 million in Q3 2025.

Alumis (ALMS) Operating Expenses (2023 - 2025) Analysis & Trends

Alumis (ALMS) has 3 years of Operating Expenses data on file, last reported at $98.4 million in Q4 2025.

  • On a quarterly basis, Operating Expenses changed 0.25% year-over-year to $98.4 million in Q4 2025; TTM through Dec 2025 was $477.9 million, a 58.89% increase from a year earlier, with the FY2025 full-year figure at $477.9 million, up 58.89% from the prior year.
  • Operating Expenses for Q4 2025 stood at $98.4 million, down from $117.4 million in the prior quarter.
  • Over the last five years, Operating Expenses for ALMS reached as high as $143.2 million in Q2 2025 and fell as low as $37.6 million in Q2 2023.
  • Historically, Operating Expenses has averaged $81.8 million across 3 years, with a median of $98.4 million in 2025.
  • On a YoY basis, Operating Expenses climbed as much as 155.09% in 2025 and fell as far as 0.25% in 2025.
  • Year by year, Operating Expenses stood at $40.1 million in 2023, then soared by 145.74% to $98.6 million in 2024, then slipped by 0.25% to $98.4 million in 2025.
  • Per Business Quant data, the three most recent Operating Expenses figures were $98.4 million in Q4 2025, $117.4 million in Q3 2025, and $143.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Alumis 2.37 Bn 2.06 Bn - 98.37 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 98.37 Mn
Sep 30, 2025 117.36 Mn
Jun 30, 2025 143.21 Mn
Mar 31, 2025 118.92 Mn
Dec 31, 2024 98.62 Mn
Sep 30, 2024 98.40 Mn
Jun 30, 2024 56.14 Mn
Mar 31, 2024 47.59 Mn
Dec 31, 2023 40.13 Mn
Sep 30, 2023 43.76 Mn
Jun 30, 2023 37.62 Mn