Alumis (ALMS) Operating Expenses (2023 - 2026)
Alumis (ALMS) posted quarterly Operating Expenses of $98.4 million for Q4 2025, little changed year-over-year from $98.6 million in Q4 2024, and down 16.18% quarter-over-quarter from $117.4 million in Q3 2025.
Alumis (ALMS) Operating Expenses (2023 - 2026) Analysis & Trends
Alumis (ALMS) has reported Operating Expenses for 3 consecutive years, with $98.4 million the latest figure, recorded in Q4 2025.
- In Q4 2025, Operating Expenses changed 0.25% year-over-year to $98.4 million; the TTM figure through Dec 2025 stood at $477.9 million (up 58.89% YoY), while the FY2025 annual figure was $477.9 million, up 58.89% from the prior year.
- Operating Expenses eased to $98.4 million in Q4 2025 per ALMS's latest filing, from $117.4 million in the prior quarter.
- Across five years, Operating Expenses topped out at $143.2 million in Q2 2025 and bottomed at $37.6 million in Q2 2023.
- Historically, Operating Expenses has averaged $81.8 million across 3 years, with a median of $98.4 million in 2025.
- On a YoY basis, Operating Expenses climbed as much as 155.09% in 2025 and fell as far as 0.25% in 2025.
- Alumis' Operating Expenses stood at $40.1 million in 2023, then jumped by 145.74% to $98.6 million in 2024, then retreated by 0.25% to $98.4 million in 2025.
- Business Quant data shows ALMS's Operating Expenses at $98.4 million in Q4 2025, $117.4 million in Q3 2025, and $143.2 million in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Alumis | 3.25 Bn | 2.75 Bn | - | 150.52 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 150.52 Mn |
| Dec 31, 2025 | 98.37 Mn |
| Sep 30, 2025 | 117.36 Mn |
| Jun 30, 2025 | 143.21 Mn |
| Mar 31, 2025 | 118.92 Mn |
| Dec 31, 2024 | 98.62 Mn |
| Sep 30, 2024 | 98.40 Mn |
| Jun 30, 2024 | 56.14 Mn |
| Mar 31, 2024 | 47.59 Mn |
| Dec 31, 2023 | 40.13 Mn |
| Sep 30, 2023 | 43.76 Mn |
| Jun 30, 2023 | 37.62 Mn |