Alumis (ALMS) Operating Expenses (2023 - 2025)

Alumis (ALMS) reported Operating Expenses of $98.4 million for Q4 2025, little changed year-over-year from $98.6 million in Q4 2024, and down 16.18% quarter-over-quarter from $117.4 million in Q3 2025.

Alumis (ALMS) Operating Expenses (2023 - 2025) Analysis & Trends

Alumis (ALMS) has 3 years of Operating Expenses data on file, last reported at $98.4 million in Q4 2025.

  • Operating Expenses for Q4 2025 came in at $98.4 million, changed 0.25% year-over-year; the trailing twelve-month figure through Dec 2025 was $477.9 million (up 58.89% YoY), and the FY2025 annual result was $477.9 million, up 58.89% from the prior year.
  • Operating Expenses fell to $98.4 million in Q4 2025 per ALMS's latest filing, from $117.4 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $143.2 million in Q2 2025 and troughed at $37.6 million in Q2 2023.
  • A 3-year average of $81.8 million and a median of $98.4 million in 2025 frame the typical range for Operating Expenses.
  • On a YoY basis, Operating Expenses climbed as much as 155.09% in 2025 and fell as far as 0.25% in 2025.
  • A 3-year view of Operating Expenses shows it stood at $40.1 million in 2023, then soared by 145.74% to $98.6 million in 2024, then fell by 0.25% to $98.4 million in 2025.
  • Business Quant data shows ALMS's Operating Expenses at $98.4 million in Q4 2025, $117.4 million in Q3 2025, and $143.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.33 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -138.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 574,669.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.96 Bn 91.96 Bn - -67.40 Mn
10 Alumis 1.99 Bn 1.90 Bn - 98.37 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 98.37 Mn
Sep 30, 2025 117.36 Mn
Jun 30, 2025 143.21 Mn
Mar 31, 2025 118.92 Mn
Dec 31, 2024 98.62 Mn
Sep 30, 2024 98.40 Mn
Jun 30, 2024 56.14 Mn
Mar 31, 2024 47.59 Mn
Dec 31, 2023 40.13 Mn
Sep 30, 2023 43.76 Mn
Jun 30, 2023 37.62 Mn