Alumis (ALMS) Operating Expenses (2023 - 2025)
Alumis (ALMS) reported Operating Expenses of $98.4 million for Q4 2025, little changed year-over-year from $98.6 million in Q4 2024, and down 16.18% quarter-over-quarter from $117.4 million in Q3 2025.
Alumis (ALMS) Operating Expenses (2023 - 2025) Analysis & Trends
Alumis (ALMS) has 3 years of Operating Expenses data on file, last reported at $98.4 million in Q4 2025.
- Operating Expenses for Q4 2025 came in at $98.4 million, changed 0.25% year-over-year; the trailing twelve-month figure through Dec 2025 was $477.9 million (up 58.89% YoY), and the FY2025 annual result was $477.9 million, up 58.89% from the prior year.
- Operating Expenses fell to $98.4 million in Q4 2025 per ALMS's latest filing, from $117.4 million in the prior quarter.
- Over five years, Operating Expenses peaked at $143.2 million in Q2 2025 and troughed at $37.6 million in Q2 2023.
- A 3-year average of $81.8 million and a median of $98.4 million in 2025 frame the typical range for Operating Expenses.
- On a YoY basis, Operating Expenses climbed as much as 155.09% in 2025 and fell as far as 0.25% in 2025.
- A 3-year view of Operating Expenses shows it stood at $40.1 million in 2023, then soared by 145.74% to $98.6 million in 2024, then fell by 0.25% to $98.4 million in 2025.
- Business Quant data shows ALMS's Operating Expenses at $98.4 million in Q4 2025, $117.4 million in Q3 2025, and $143.2 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | Alumis | 1.99 Bn | 1.90 Bn | - | 98.37 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 98.37 Mn |
| Sep 30, 2025 | 117.36 Mn |
| Jun 30, 2025 | 143.21 Mn |
| Mar 31, 2025 | 118.92 Mn |
| Dec 31, 2024 | 98.62 Mn |
| Sep 30, 2024 | 98.40 Mn |
| Jun 30, 2024 | 56.14 Mn |
| Mar 31, 2024 | 47.59 Mn |
| Dec 31, 2023 | 40.13 Mn |
| Sep 30, 2023 | 43.76 Mn |
| Jun 30, 2023 | 37.62 Mn |