Alector (ALEC) EBITDA Margin (2018 - 2026)
Alector's (ALEC) quarterly EBITDA Margin came in at 2382.31% in Q1 2026, down 116579.0% year-on-year from N/an in Q1 2025, and down 275.54% on a QoQ basis from 634.38% in Q4 2025.
Alector (ALEC) EBITDA Margin (2018 - 2026) Analysis & Trends
Alector (ALEC) has 9 years of EBITDA Margin data on file, last reported at 2382.31% in Q1 2026.
- On a quarterly basis, EBITDA Margin fell 116579.0% year-over-year to 2382.31% in Q1 2026; TTM through Mar 2026 was 739.7%, a 57445.0% decrease from a year earlier, with the FY2025 full-year figure at 741.3%, down 59711.0% from the prior year.
- EBITDA Margin for Q1 2026 stood at 2382.31%, down from 634.38% in the prior quarter.
- Over the last five years, EBITDA Margin for ALEC reached as high as 11.87% in Q2 2022 and fell as low as 2382.31% in Q1 2026.
- Historically, EBITDA Margin has averaged 516.33% across 5 years, with a median of 315.7% in 2024.
- Across the five-year window, EBITDA Margin surged 110037 bps in 2022 and plunged 116579 bps in 2026, its largest moves.
- Year by year, EBITDA Margin stood at 383.92% in 2022, then grew by 19 bps to 312.4% in 2023, then surged by 96 bps to 13.36% in 2024, then slumped by 4647 bps to 634.38% in 2025, then plunged by 276 bps to 2382.31% in 2026.
- Per Business Quant data, the three most recent EBITDA Margin figures were 2382.31% in Q1 2026, 634.38% in Q4 2025, and 1153.62% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Alector | 164.78 Mn | -41.74 Mn | - | -2,382.31% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -2,382.31% |
| Dec 31, 2025 | -634.38% |
| Sep 30, 2025 | -1,153.62% |
| Jun 30, 2025 | -433.55% |
| Mar 31, 2025 | -1,216.52% |
| Dec 31, 2024 | -13.36% |
| Sep 30, 2024 | -315.70% |
| Jun 30, 2024 | -302.37% |
| Mar 31, 2024 | -275.01% |
| Dec 31, 2023 | -312.40% |
| Sep 30, 2023 | -555.31% |
| Jun 30, 2023 | -6.38% |
| Mar 31, 2023 | -302.83% |
| Dec 31, 2022 | -383.92% |
| Sep 30, 2022 | -321.49% |
| Jun 30, 2022 | 11.87% |
| Mar 31, 2022 | -180.29% |
| Dec 31, 2021 | -398.23% |
| Sep 30, 2021 | 69.25% |
| Jun 30, 2021 | -842.34% |