Alector (ALEC) Net Margin (2018 - 2026)
Alector (ALEC) posted quarterly Net Margin of 2192.16% for Q1 2026, down 109061.0% year-over-year from N/an in Q1 2025, and down 268.54% quarter-over-quarter from 594.82% in Q4 2025.
Alector (ALEC) Net Margin (2018 - 2026) Analysis & Trends
Alector (ALEC) has reported Net Margin for 9 consecutive years, with 2192.16% the latest figure, recorded in Q1 2026.
- In Q1 2026, Net Margin fell 109061.0% year-over-year to 2192.16%; the TTM figure through Mar 2026 stood at 679.92% (down 54018.0% YoY), while the FY2025 annual figure was 678.36%, down 55997.0% from the prior year.
- Net Margin eased to 2192.16% in Q1 2026 per ALEC's latest filing, from 594.82% in the prior quarter.
- Across five years, Net Margin topped out at 12.38% in Q2 2022 and bottomed at 2192.16% in Q1 2026.
- Historically, Net Margin has averaged 467.31% across 5 years, with a median of 277.1% in 2023.
- Annual changes were most pronounced in 2022 — Net Margin jumped 108706 bps — and 2026, when it sank 109061 bps.
- Alector's Net Margin stood at 363.07% in 2022, then jumped by 35 bps to 235.62% in 2023, then surged by 98 bps to 3.82% in 2024, then sank by 15456 bps to 594.82% in 2025, then slumped by 269 bps to 2192.16% in 2026.
- Business Quant data shows ALEC's Net Margin at 2192.16% in Q1 2026, 594.82% in Q4 2025, and 1063.4% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 32.99% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 30.23% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 30.33% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 13.90% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 30.98% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 12.09% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 12.74% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -3.12% |
| 10 | Alector | 218.85 Mn | 46.05 Mn | - | -692.47% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -692.47% |
| Mar 31, 2026 | -2,192.16% |
| Dec 31, 2025 | -594.82% |
| Sep 30, 2025 | -1,063.40% |
| Jun 30, 2025 | -387.66% |
| Mar 31, 2025 | -1,101.55% |
| Dec 31, 2024 | -3.82% |
| Sep 30, 2024 | -275.19% |
| Jun 30, 2024 | -256.42% |
| Mar 31, 2024 | -227.01% |
| Dec 31, 2023 | -235.62% |
| Sep 30, 2023 | -488.25% |
| Jun 30, 2023 | 2.45% |
| Mar 31, 2023 | -277.10% |
| Dec 31, 2022 | -363.07% |
| Sep 30, 2022 | -310.72% |
| Jun 30, 2022 | 12.38% |
| Mar 31, 2022 | -182.30% |
| Dec 31, 2021 | -342.87% |
| Sep 30, 2021 | 69.40% |