Alector, Inc. (ALEC) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

101,961,765Shares Outstanding

6,606,039Shares held by institutions

$13,013,897Value of institutional holdings

79.60%Institutional ownership %

31.84%Shares Changed QoQ

119No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Alector, Inc. (NASDAQ:ALEC) currently has 119 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

Alector saw its institutional ownership percentage rose to 79.6% in December 2025 from 73.3% in September 2025.
The company experienced a 31.84% quarterly change in institutional shares held, alongside a decrease of 18.49% in total owners annually.
Among the 119 institutional holders of Alector, 58 added to their stakes while 38 trimmed their positions and 23 held steady.
The total number of shares held by institutions in Alector increased to 81.16Mn as of December 2025, a net change of up by 19.60Mn shares quarter on quarter, and up 7.86Mn shares year over year.
TCG Crossover Management, LLC continues to be the largest institutional holder of Alector as of December 31, 2025, with a position of 10.00Mn shares, representing 9.81% of the company's outstanding stock.
Among the most significant buyers of Alector during December 2025 were TCG Crossover Management, LLC (10.00Mn), Foresite Capital Management IV, LLC (3.89Mn), BALYASNY ASSET MANAGEMENT L.P. (3.27Mn), 683 Capital Management, LLC (2.35Mn), Kynam Capital Management, LP (2.00Mn).
Leading sellers of Alector stock in December 2025 included FMR LLC (12.95Mn), ROYAL BANK OF CANADA (623.97K), Eversept Partners, LP (482.56K), BARCLAYS PLC (474.69K), CITADEL ADVISORS LLC (378.03K).
The top 10 institutional holders of Alector for the quarter ending December 2025 included TCG Crossover Management, LLC (10.00Mn), BlackRock, Inc. (7.15Mn), VANGUARD GROUP INC (6.91Mn), Foresite Capital Management IV, LLC (3.89Mn), Merck & Co., Inc. (3.55Mn), ACADIAN ASSET MANAGEMENT LLC (3.44Mn), 683 Capital Management, LLC (3.35Mn), BALYASNY ASSET MANAGEMENT L.P. (3.27Mn), D. E. Shaw & Co., Inc. (2.37Mn), FMR LLC (2.23Mn).

119 Institutional Holders

6,606,039 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
TCG Crossover Management, LLC	31 Dec, 2025	10,000,000	10,000,000	0.00%	$15,600,000.00
BlackRock, Inc.	31 Dec, 2025	7,147,766	-50,207	-0.70%	$11,150,515.00
VANGUARD GROUP INC	31 Dec, 2025	6,908,054	873,395	14.47%	$10,776,564.00
Foresite Capital Management IV, LLC	31 Dec, 2025	3,887,200	3,887,200	0.00%	$6,064,032.00
Merck & Co., Inc.	31 Dec, 2025	3,545,719	0	0.00%	$5,531,322.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	3,442,449	1,069,464	45.07%	$5,362.00
683 Capital Management, LLC	31 Dec, 2025	3,350,000	2,350,000	235.00%	$5,226,000.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	3,265,575	3,265,575	0.00%	$5,094,297.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	2,365,151	1,386,947	141.79%	$3,689,636.00
FMR LLC	31 Dec, 2025	2,231,171	-12,950,678	-85.30%	$3,480,627.00
JACOBS LEVY EQUITY MANAGEMENT, INC	31 Dec, 2025	2,173,202	942,228	76.54%	$3,390,195.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,075,220	213,962	11.50%	$3,238,029.00
Kynam Capital Management, LP	31 Dec, 2025	2,000,000	2,000,000	0.00%	$3,120,000.00
STATE STREET CORP	31 Dec, 2025	1,814,298	79,619	4.59%	$2,830,305.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,543,650	594,500	62.63%	$2,408,094.00
MEDICI CAPITAL LLC	31 Dec, 2025	1,500,520	1,018,546	211.33%	$2,340,811.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,332,914	177,887	15.40%	$2,079,346.00
Euclidean Capital LLC	31 Dec, 2025	1,307,858	0	0.00%	$2,040,258.00
MARSHALL WACE, LLP	31 Dec, 2025	1,166,817	1,015,174	669.45%	$1,820,234.00
Spruce Street Capital LP	31 Dec, 2025	1,117,986	1,117,986	0.00%	$1,744,058.00

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