Xenon Pharmaceuticals XENE Institutional Ownership

NASDAQ XENE

$36.54 +0.59 (+1.63%)

As of: Oct 22, 2026 · 9:51 AM EDT

Institutions by Trading Activity

314 Institutions

Increased 175 55.7%

Unchanged 53 16.9%

Reduced 86 27.4%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

—

13F totals exceed reported shares outstanding

Shares Held by Institutions

101.06Mn

of 99.61Mn outstanding

▲+0.88% QoQ

Shares Outstanding

99.61Mn

Institutional Investors

314

filed 13F for Jun 2026

▲+27 vs prior quarter

Net Shares Added (QoQ)

+882.51K

accumulated since last quarter

Value of Holdings

$3.67Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 11, 2026

Xenon Pharmaceuticals Inc. (NASDAQ:XENE) was reported as a holding by 314 institutional investors in 13F filings for the quarter ended June 30, 2026.

Total shares held in Xenon Pharmaceuticals rose 0.88% from Q1 2026, while the number of holders rose 55.45% from Q2 2025.
Of these 314 holders, 175 added to their positions, 86 reduced their stakes and 53 left their positions unchanged.
Institutional investors held 101.06Mn shares of Xenon Pharmaceuticals in total at the end of Q2 2026, up 882.51K from the prior quarter and up 18.45Mn from a year earlier.
FMR LLC led 13F holders of XENE with 9.65Mn shares as of June 30, 2026.
The biggest increases in XENE positions during Q2 2026 came from T. Rowe Price Associates Inc (+1.92Mn shares), BlackRock, Inc. (+1.88Mn shares), T. Rowe Price Investment Management, Inc. (+1.22Mn shares), Two Sigma Investments, LP (+1.04Mn shares) and Invesco Ltd. (+844.36K shares).
Holders that trimmed the most shares of Xenon Pharmaceuticals in Q2 2026 while keeping a position were Wellington Management Group LLP (-3.4Mn shares), Citadel Advisors LLC (-1.25Mn shares), FMR LLC (-1.17Mn shares), Jennison Associates LLC (-1.11Mn shares) and Alyeska Investment Group, L.P. (-601.78K shares).
Per Business Quant data, the 10 largest holders of Xenon Pharmaceuticals at the end of Q2 2026 were FMR LLC (9.65Mn shares), BlackRock, Inc. (7.52Mn shares), Avoro Capital Advisors LLC (5.78Mn shares), Polar Capital Holdings PLC (4.57Mn shares), Driehaus Capital Management LLC (4.42Mn shares), Jupiter Topco LLC (4.19Mn shares), T. Rowe Price Associates Inc (3.25Mn shares), JPMorgan Chase & Co (2.62Mn shares), Capital International Investors (2.36Mn shares) and T. Rowe Price Investment Management, Inc. (2.17Mn shares).

Form 13F Holdings

315 Institutional Holders

Report period 30 Jun, 2026

Total shares held 101.06Mn

Of outstanding —

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	FMR LLC	0000315066	9,647,998	9.69%	▼1,170,493	-10.82%	$582.35Mn
2	BlackRock, Inc.	0002012383	7,522,482	7.55%	▲1,882,364	+33.37%	$454.06Mn
3	Avoro Capital Advisors LLC	0001633313	5,777,777	5.80%	0	0.00%	$348.75Mn
4	Polar Capital Holdings Plc	0001837309	4,570,556	4.59%	▲165,244	+3.75%	$275.88Mn
5	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	4,418,557	4.44%	▼73,096	-1.63%	$266.70Mn
6	Jupiter Topco LLC	0002146052	4,186,519	4.20%	▲4,186,519	0.00%	$252.67Mn
7	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	3,248,219	3.26%	▲1,918,628	+144.30%	$196.06K
8	Jpmorgan Chase & Co	0000019617	2,617,360	2.63%	▲693,750	+36.07%	$157.38Mn
9	Capital International Investors	0001562230	2,361,639	2.37%	▼313,088	-11.71%	$142.55Mn
10	T. Rowe Price Investment Management, Inc.	0001897612	2,168,581	2.18%	▲1,216,626	+127.80%	$130.90K
11	State Street Corp	0000093751	1,969,629	1.98%	▲249,096	+14.48%	$118.89Mn
12	TWO SIGMA INVESTMENTS, LP	0001179392	1,642,848	1.65%	▲1,036,763	+171.06%	$99.16Mn
13	DEERFIELD MANAGEMENT COMPANY, L.P.	0001009258	1,615,696	1.62%	0	0.00%	$97.52Mn
14	Affinity Asset Advisors, LLC	0001773195	1,595,000	1.60%	▼80,000	-4.78%	$96.27Mn
15	ALLIANCEBERNSTEIN L.P.	0001109448	1,562,276	1.57%	▲158,979	+11.33%	$90.85Mn
16	WESTFIELD CAPITAL MANAGEMENT CO LP	0001177719	1,507,294	1.51%	▲105,811	+7.55%	$90.98Mn
17	Franklin Templeton Inc	0000038777	1,437,712	1.44%	▲157,135	+12.27%	$86.78Mn
18	WELLINGTON MANAGEMENT GROUP LLP	0000902219	1,425,492	1.43%	▼3,404,149	-70.48%	$86.04Mn
19	CITADEL ADVISORS LLC	0001423053	1,401,242	1.41%	▼1,251,748	-47.18%	$84.58Mn
20	GEODE CAPITAL MANAGEMENT, LLC	0001214717	1,370,114	1.38%	▲277,182	+25.36%	$82.69Mn

Showing 1 to 20 of 315 holders