Taysha Gene Therapies TSHA Institutional Ownership

NASDAQ TSHA

$4.03 -0.09 (-2.30%)

As of: Oct 22, 2026 · 10:37 AM EDT

Institutions by Trading Activity

209 Institutions

Increased 140 67.0%

Unchanged 27 12.9%

Reduced 42 20.1%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

81.17%

▲+8.69 pp QoQ

Shares Held by Institutions

299.56Mn

of 369.04Mn outstanding

▲+12.72% QoQ

Shares Outstanding

369.04Mn

69.48Mn held outside 13F filers

Institutional Investors

209

filed 13F for Jun 2026

▲+18 vs prior quarter

Net Shares Added (QoQ)

+33.80Mn

accumulated since last quarter

Value of Holdings

$1.23Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 11, 2026

Taysha Gene Therapies, Inc. (NASDAQ:TSHA) counted 209 institutional investors among its 13F-reported shareholders for the quarter ended June 30, 2026.

These investors held 81.17% of Taysha Gene Therapies' outstanding shares at the end of Q2 2026, up from 72.49% in Q1 2026.
Total holdings of TSHA shares rose 12.72% from Q1 2026, and the holder count rose 42.18% from Q2 2025.
Of the 209 holders, 140 added to their positions, 42 reduced their stakes and 27 left their positions unchanged in Q2 2026.
In total, institutional investors held 299.56Mn shares of Taysha Gene Therapies at the end of Q2 2026, up 33.8Mn from the prior quarter and up 59.25Mn from a year earlier.
Avoro Capital Advisors LLC was the top holder of Taysha Gene Therapies as of June 30, 2026, with 23.89Mn shares, or 6.47% of shares outstanding.
Among holders that already owned Taysha Gene Therapies, the biggest buyers in Q2 2026 were Wellington Management Group LLP (+3.35Mn shares), Pictet Asset Management Holding SA (+2.75Mn shares), BlackRock, Inc. (+2.33Mn shares), Vanguard Capital Management LLC (+2.25Mn shares) and Avoro Capital Advisors LLC (+2.19Mn shares).
The biggest cuts to TSHA positions during Q2 2026 came from SG Americas Securities, LLC (-1.97Mn shares), Morgan Stanley (-1.48Mn shares), Barclays PLC (-1.18Mn shares), Millennium Management LLC (-1.15Mn shares) and FMR LLC (-984.84K shares).
Per Business Quant, the top 10 investors in TSHA for the quarter ended June 30, 2026 were Avoro Capital Advisors LLC (23.89Mn shares), Ra Capital Management, L.P. (23.56Mn shares), Goldman Sachs Group Inc (22.71Mn shares), BlackRock, Inc. (20.69Mn shares), Vestal Point Capital, LP (19.41Mn shares), Morgan Stanley (16.49Mn shares), RTW Investments, LP (13.56Mn shares), FMR LLC (13.34Mn shares), Vanguard Capital Management LLC (12.48Mn shares) and State Street Corp (11.42Mn shares).

Form 13F Holdings

209 Institutional Holders

Report period 30 Jun, 2026

Total shares held 299.56Mn

Of outstanding 81.17%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	Avoro Capital Advisors LLC	0001633313	23,888,888	6.47%	▲2,188,888	+10.09%	$162.68Mn
2	RA CAPITAL MANAGEMENT, L.P.	0001346824	23,555,648	6.38%	0	0.00%	$160.41Mn
3	Goldman Sachs Group Inc	0000886982	22,713,118	6.15%	▲343,473	+1.54%	$154.68Mn
4	BlackRock, Inc.	0002012383	20,691,927	5.61%	▲2,326,319	+12.67%	$140.91Mn
5	Vestal Point Capital, LP	0001974915	19,415,000	5.26%	▲1,415,000	+7.86%	$132.22Mn
6	Morgan Stanley	0000895421	16,487,479	4.47%	▼1,477,892	-8.23%	$112.28Mn
7	RTW INVESTMENTS, LP	0001493215	13,560,258	3.67%	▼119,990	-0.88%	$92.35Mn
8	FMR LLC	0000315066	13,336,413	3.61%	▼984,842	-6.88%	$90.82Mn
9	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	12,478,595	3.38%	▲2,247,093	+21.96%	$84.98Mn
10	State Street Corp	0000093751	11,421,920	3.10%	▲212,842	+1.90%	$77.78Mn
11	Siren, L.L.C.	0002005245	9,846,579	2.67%	▲1,016,666	+11.51%	$67.06Mn
12	Octagon Capital Advisors LP	0001839435	9,693,244	2.63%	▲833,333	+9.41%	$66.01Mn
13	GEODE CAPITAL MANAGEMENT, LLC	0001214717	6,560,394	1.78%	▲1,028,439	+18.59%	$44.69Mn
14	Polar Capital Holdings Plc	0001837309	5,117,133	1.39%	▼537,207	-9.50%	$34.85Mn
15	MPM BioImpact LLC	0001687078	4,500,000	1.22%	▲4,500,000	0.00%	$30.65Mn
16	D. E. Shaw & Co., Inc.	0001009207	4,398,652	1.19%	▼28,649	-0.65%	$29.95Mn
17	BAKER BROS. ADVISORS LP	0001263508	4,004,756	1.09%	0	0.00%	$27.27Mn
18	WELLINGTON MANAGEMENT GROUP LLP	0000902219	3,975,605	1.08%	▲3,349,244	+534.71%	$27.07Mn
19	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0001535845	3,885,501	1.05%	▲1,002,200	+34.76%	$26.46Mn
20	Casdin Capital, LLC	0001534261	3,250,000	0.88%	0	0.00%	$22.13Mn

Showing 1 to 20 of 209 holders