SOPHiA GENETICS SOPH Institutional Ownership

Updated Oct 5, 2026

SOPHiA GENETICS SA (NASDAQ:SOPH) was held by 71 institutional investors that filed 13F reports for the quarter ended June 30, 2026.

• Together they owned 54.22% of the outstanding stock in Q2 2026, up from 35.69% a quarter earlier.
• Total shares held in SOPH rose 51.93% from Q1 2026; the number of holders rose 136.67% from Q2 2025.
• Of these 71 holders, 42 added to their positions, 16 reduced their stakes and 13 left their positions unchanged.
• Combined, institutional investors held 36.62Mn shares of SOPH as of Q2 2026, up 12.52Mn from the prior quarter and up 20.28Mn from a year earlier.
• Generation Investment Management LLP was the top holder of SOPHiA GENETICS as of June 30, 2026, with 6.79Mn shares, or 10.05% of shares outstanding.
• The biggest increases in SOPH positions during Q2 2026 came from Royce & Associates LP (+1.57Mn shares), Principal Financial Group Inc (+955.01K shares), Archon Capital Management LLC (+250K shares), Millennium Management LLC (+128.27K shares) and Renaissance Technologies LLC (+53.5K shares).
• The largest position reductions in SOPH for Q2 2026 were by Soleus Capital Management, L.P. (-285K shares), SEI Investments Co (-192.84K shares), Federated Hermes, Inc. (-48.02K shares), Rathbones Group PLC (-37K shares) and Essex Investment Management Co LLC (-29.38K shares).
• Business Quant data shows the 10 biggest positions in SOPHiA GENETICS as of Q2 2026 were held by Generation Investment Management LLP (6.79Mn shares), AIGH Capital Management LLC (3.95Mn shares), Akre Capital Management LLC (3.72Mn shares), Royce & Associates LP (3.38Mn shares), Principal Financial Group Inc (2.36Mn shares), Ameriprise Financial Inc (2.22Mn shares), Banque Pictet & Cie SA (2.21Mn shares), AWM Investment Company, Inc. (1.7Mn shares), Soleus Capital Management, L.P. (1.56Mn shares) and Silvercrest Asset Management Group LLC (1.43Mn shares).