Praxis Precision Medicines PRAX Institutional Ownership

NASDAQ PRAX

$256.47 -8.02 (-3.03%)

At close: Oct 21, 2026 · 4:00 PM EDT

As of the 13F quarter ended Jun 30, 2026, 308 institutions reported holding Praxis Precision Medicines (PRAX) shares. Versus the prior quarter, the holder count rose by 20 and shares held were up 5.96%. The largest holder is Jupiter Topco LLC with 3.42Mn shares (11.74% of outstanding).

Updated Oct 10, 2026 Praxis Precision Medicines (PRAX) stock price and overview

Institutions by Trading Activity

308 Institutions

Increased 181 58.8%

Unchanged 34 11.0%

Reduced 93 30.2%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

—

13F totals exceed reported shares outstanding

Shares Held by Institutions

33.69Mn

of 29.13Mn outstanding

▲+5.96% QoQ

Shares Outstanding

29.13Mn

Institutional Investors

308

filed 13F for Jun 2026

▲+20 vs prior quarter

Net Shares Added (QoQ)

+1.89Mn

accumulated since last quarter

Value of Holdings

$8.91Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 10, 2026

Praxis Precision Medicines, Inc. (NASDAQ:PRAX) counted 308 institutional investors among its 13F-reported shareholders for the quarter ended June 30, 2026.

Total shares held in Praxis Precision Medicines rose 5.96% from Q1 2026, while the number of holders rose 121.58% from Q2 2025.
Of the 308 holders of PRAX in Q2 2026, 181 added to their positions, 93 reduced their stakes and 34 left their positions unchanged.
Combined, institutional investors held 33.69Mn shares of PRAX as of Q2 2026, up 1.89Mn from the prior quarter and up 10.8Mn from a year earlier.
Jupiter Topco LLC was the top holder of Praxis Precision Medicines as of June 30, 2026, with 3.42Mn shares.
Holders that added the most shares of Praxis Precision Medicines in Q2 2026 were Vanguard Portfolio Management LLC (+578.44K shares), Invesco Ltd. (+476.15K shares), T. Rowe Price Associates Inc (+312.15K shares), Westfield Capital Management Co LP (+218.24K shares) and Adage Capital Partners GP, L.L.C. (+199.74K shares).
Holders that trimmed the most shares of Praxis Precision Medicines in Q2 2026 while keeping a position were Orbis Allan Gray Ltd (-942.69K shares), Cormorant Asset Management, LP (-245.5K shares), Goldman Sachs Group Inc (-161.9K shares), Soleus Capital Management, L.P. (-153K shares) and ArrowMark Colorado Holdings LLC (-71.82K shares).
According to Business Quant data, the leading holders of PRAX for Q2 2026 were Jupiter Topco LLC (3.42Mn shares), FMR LLC (2.32Mn shares), BlackRock, Inc. (2.29Mn shares), Perceptive Advisors LLC (2.04Mn shares), Baker Bros. Advisors LP (1.75Mn shares), Orbis Allan Gray Ltd (1.53Mn shares), Vanguard Portfolio Management LLC (1.34Mn shares), Vanguard Capital Management LLC (1.24Mn shares), State Street Corp (1.03Mn shares) and Adage Capital Partners GP, L.L.C. (1.02Mn shares).

Form 13F Holdings

310 Institutional Holders

Report period 30 Jun, 2026

Total shares held 33.69Mn

Of outstanding —

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	Jupiter Topco LLC	0002146052	3,421,374	11.74%	▲3,421,374	0.00%	$1.15Bn
2	FMR LLC	0000315066	2,316,907	7.95%	▲155,964	+7.22%	$775.68Mn
3	BlackRock, Inc.	0002012383	2,292,585	7.87%	▼32,344	-1.39%	$767.53Mn
4	PERCEPTIVE ADVISORS LLC	0001224962	2,035,986	6.99%	0	0.00%	$681.63Mn
5	BAKER BROS. ADVISORS LP	0001263508	1,753,198	6.02%	0	0.00%	$586.95Mn
6	Orbis Allan Gray Ltd	0001663865	1,529,788	5.25%	▼942,692	-38.13%	$512.16Mn
7	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	1,335,185	4.58%	▲578,437	+76.44%	$447.01Mn
8	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	1,235,299	4.24%	▲13,355	+1.09%	$413.57Mn
9	State Street Corp	0000093751	1,026,443	3.52%	▲142,205	+16.08%	$343.66Mn
10	ADAGE CAPITAL PARTNERS GP, L.L.C.	0001165408	1,015,480	3.49%	▲199,741	+24.49%	$339.97Mn
11	DEERFIELD MANAGEMENT COMPANY, L.P.	0001009258	963,351	3.31%	0	0.00%	$322.52Mn
12	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	959,048	3.29%	▲9,823	+1.03%	$321.08Mn
13	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	942,999	3.24%	▲312,147	+49.48%	$315.71K
14	Morgan Stanley	0000895421	854,112	2.93%	▲20,621	+2.47%	$285.95Mn
15	GEODE CAPITAL MANAGEMENT, LLC	0001214717	748,039	2.57%	▲97,135	+14.92%	$250.48Mn
16	Cormorant Asset Management, LP	0001583977	640,000	2.20%	▼245,500	-27.72%	$214.27Mn
17	Goldman Sachs Group Inc	0000886982	548,830	1.88%	▼161,904	-22.78%	$183.74Mn
18	Bank Of America Corp /De/	0000070858	546,930	1.88%	▲12,326	+2.31%	$183.11Mn
19	Invesco Ltd.	0000914208	537,548	1.85%	▲476,151	+775.53%	$179.97Mn
20	Hood River Capital Management LLC	0001578177	425,167	1.46%	▲66,549	+18.56%	$142.34Mn

Showing 1 to 20 of 310 holders