Zymeworks (ZYME) Operating Expenses (2021 - 2026)
Zymeworks (ZYME) posted Operating Expenses of $49.5 million for Q1 2026, up 6.13% sequentially from $46.7 million in Q4 2025, and down 6.06% YoY from $52.7 million in Q1 2025.
Zymeworks (ZYME) Operating Expenses (2021 - 2026) Analysis & Trends
Zymeworks has reported Operating Expenses for 6 years, with the latest figure at $49.5 million in Q1 2026.
- Quarterly Operating Expenses fell 6.06% year-over-year to $49.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $195.3 million (down 10.53% YoY) and the FY2025 annual result came in at $198.5 million, down 6.98% from the prior year.
- Operating Expenses improved to $49.5 million in Q1 2026 per ZYME's latest filing, from $46.7 million in the prior quarter.
- Over five years, Operating Expenses peaked at $83.1 million in Q4 2022 and troughed at $40.3 million in Q4 2023.
- A 5-year average of $56.3 million and a median of $52.7 million in 2025 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2022 and 2023: Operating Expenses surged 36.86% in 2022, then slumped 51.45% in 2023.
- Over 5 years, Operating Expenses stood at $83.1 million in 2022, then plunged by 51.45% to $40.3 million in 2023, then jumped by 31.98% to $53.2 million in 2024, then fell by 12.36% to $46.7 million in 2025, then advanced by 6.13% to $49.5 million in 2026.
- According to Business Quant data, Operating Expenses over the past three periods registered $49.5 million, $46.7 million, and $49.7 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Zymeworks | 1.79 Bn | 1.52 Bn | - | 46.77 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 46.77 Mn |
| Mar 31, 2026 | 49.53 Mn |
| Dec 31, 2025 | 46.67 Mn |
| Sep 30, 2025 | 49.72 Mn |
| Jun 30, 2025 | 49.40 Mn |
| Mar 31, 2025 | 52.72 Mn |
| Dec 31, 2024 | 53.25 Mn |
| Sep 30, 2024 | 50.21 Mn |
| Jun 30, 2024 | 62.13 Mn |
| Mar 31, 2024 | 47.83 Mn |
| Dec 31, 2023 | 40.35 Mn |
| Sep 30, 2023 | 49.74 Mn |
| Jun 30, 2023 | 61.12 Mn |
| Mar 31, 2023 | 62.86 Mn |
| Dec 31, 2022 | 83.10 Mn |
| Sep 30, 2022 | 52.99 Mn |
| Jun 30, 2022 | 71.27 Mn |
| Mar 31, 2022 | 74.60 Mn |
| Dec 31, 2021 | 60.72 Mn |
| Sep 30, 2021 | 65.36 Mn |