Zymeworks (ZYME) Operating Expenses (2021 - 2026)
Zymeworks recorded quarterly Operating Expenses of $49.5 million in Q1 2026, up 6.13% quarter-over-quarter from $46.7 million in Q4 2025, and down 6.06% year-over-year from $52.7 million in Q1 2025.
Zymeworks' Operating Expenses history runs 6 years deep, the most recent figure standing at $49.5 million for Q1 2026.
- In Q1 2026, Operating Expenses fell 6.06% year-over-year to $49.5 million; the TTM figure through Mar 2026 stood at $195.3 million (down 10.53% YoY), while the FY2025 annual figure was $198.5 million, down 6.98% from the prior year.
- Operating Expenses came in at $49.5 million for Q1 2026 at Zymeworks, up from $46.7 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $83.1 million in Q4 2022 to a low of $40.3 million in Q4 2023.
- A 5-year average of $56.3 million and a median of $52.7 million in 2025 frame the typical range for Operating Expenses.
- Across the five-year window, Operating Expenses jumped 36.86% in 2022 and sank 51.45% in 2023, its largest moves.
- Zymeworks' Operating Expenses stood at $83.1 million in 2022, then tumbled by 51.45% to $40.3 million in 2023, then soared by 31.98% to $53.2 million in 2024, then declined by 12.36% to $46.7 million in 2025, then gained by 6.13% to $49.5 million in 2026.
- According to Business Quant data, Operating Expenses over the past three periods registered $49.5 million, $46.7 million, and $49.7 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.97 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 4.33 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -138.30 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 15.76 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.85 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 2.96 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 898.54 Mn |
| 10 | Zymeworks | 1.84 Bn | 1.47 Bn | - | 49.53 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 49.53 Mn |
| Dec 31, 2025 | 46.67 Mn |
| Sep 30, 2025 | 49.72 Mn |
| Jun 30, 2025 | 49.40 Mn |
| Mar 31, 2025 | 52.72 Mn |
| Dec 31, 2024 | 53.25 Mn |
| Sep 30, 2024 | 50.21 Mn |
| Jun 30, 2024 | 62.13 Mn |
| Mar 31, 2024 | 47.83 Mn |
| Dec 31, 2023 | 40.35 Mn |
| Sep 30, 2023 | 49.74 Mn |
| Jun 30, 2023 | 61.12 Mn |
| Mar 31, 2023 | 62.86 Mn |
| Dec 31, 2022 | 83.10 Mn |
| Sep 30, 2022 | 52.99 Mn |
| Jun 30, 2022 | 71.27 Mn |
| Mar 31, 2022 | 74.60 Mn |
| Dec 31, 2021 | 60.72 Mn |
| Sep 30, 2021 | 65.36 Mn |