Zymeworks (ZYME) Operating Expenses (2021 - 2026)

Zymeworks (ZYME) reported Operating Expenses of $49.5 million for Q1 2026, down 6.06% on a YoY basis from $52.7 million in Q1 2025, and up 6.13% sequentially from $46.7 million in Q4 2025.

Zymeworks (ZYME) Operating Expenses (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of Operating Expenses data on file, last reported at $49.5 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses fell 6.06% year-over-year to $49.5 million; the trailing twelve-month figure through Mar 2026 stood at $195.3 million (down 10.53% YoY), and the FY2025 full-year result was $198.5 million, down 6.98% from the prior year.
  • Operating Expenses improved to $49.5 million in Q1 2026, from $46.7 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $83.1 million in Q4 2022 to a low of $40.3 million in Q4 2023.
  • A 5-year average of $56.3 million and a median of $52.7 million in 2025 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses soared 36.86% in 2022 and plunged 51.45% in 2023, its largest moves.
  • Tracing ZYME's Operating Expenses over 5 years: stood at $83.1 million in 2022, then sank by 51.45% to $40.3 million in 2023, then jumped by 31.98% to $53.2 million in 2024, then slipped by 12.36% to $46.7 million in 2025, then increased by 6.13% to $49.5 million in 2026.
  • Business Quant data shows ZYME's Operating Expenses at $49.5 million in Q1 2026, $46.7 million in Q4 2025, and $49.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Zymeworks 1.73 Bn 1.36 Bn - 49.53 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 49.53 Mn
Dec 31, 2025 46.67 Mn
Sep 30, 2025 49.72 Mn
Jun 30, 2025 49.40 Mn
Mar 31, 2025 52.72 Mn
Dec 31, 2024 53.25 Mn
Sep 30, 2024 50.21 Mn
Jun 30, 2024 62.13 Mn
Mar 31, 2024 47.83 Mn
Dec 31, 2023 40.35 Mn
Sep 30, 2023 49.74 Mn
Jun 30, 2023 61.12 Mn
Mar 31, 2023 62.86 Mn
Dec 31, 2022 83.10 Mn
Sep 30, 2022 52.99 Mn
Jun 30, 2022 71.27 Mn
Mar 31, 2022 74.60 Mn
Dec 31, 2021 60.72 Mn
Sep 30, 2021 65.36 Mn