Xilio Therapeutics (XLO) Return on Sales (2024 - 2026)

Xilio Therapeutics (XLO) reported Return on Sales of 0.01% for Q1 2026, up 4.0% on a YoY basis from 0.01% in Q1 2025, and down 28.89% sequentially from 0.01% in Q4 2025.

Xilio Therapeutics (XLO) Return on Sales (2024 - 2026) Analysis & Trends

Xilio Therapeutics (XLO) has 3 years of Return on Sales data on file, last reported at 0.01% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Sales rose 4.0% year-over-year to 0.01%; the trailing twelve-month figure through Mar 2026 stood at 0.01% (up 5.0% YoY), and the FY2025 full-year result was 0.04%, up 23.0% from the prior year.
  • Return on Sales fell to 0.01% in Q1 2026, from 0.01% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.0% in Q3 2025 to a low of 0.08% in Q4 2024.
  • A 3-year average of 0.04% and a median of 0.03% in 2025 frame the typical range for Return on Sales.
  • Across the five-year window, Return on Sales advanced 7 bps in 2025 and advanced 4 bps in 2026, its largest moves.
  • Tracing XLO's Return on Sales over 3 years: stood at 0.08% in 2024, then surged by 89 bps to 0.01% in 2025, then dropped by 29 bps to 0.01% in 2026.
  • Business Quant data shows XLO's Return on Sales at 0.01% in Q1 2026, 0.01% in Q4 2025, and 0.0% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 0.00%
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 0.00%
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.35 Bn 37.35 Bn - -
10 Xilio Therapeutics 148.60 Mn -1.70 Mn - -0.01%

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.01%
Dec 31, 2025 -0.01%
Sep 30, 2025 0.00%
Jun 30, 2025 -0.02%
Mar 31, 2025 -0.05%
Dec 31, 2024 -0.08%
Sep 30, 2024 -0.07%
Jun 30, 2024 -0.06%