Xilio Therapeutics (XLO) Return on Sales (2024 - 2026)
Xilio Therapeutics (XLO) posted Return on Sales of 0.01% for Q1 2026, down 28.89% sequentially from 0.01% in Q4 2025, and up 4.0% YoY from 0.01% in Q1 2025.
Xilio Therapeutics (XLO) Return on Sales (2024 - 2026) Analysis & Trends
Xilio Therapeutics has reported Return on Sales for 3 years, with the latest figure at 0.01% in Q1 2026.
- Quarterly Return on Sales rose 4.0% year-over-year to 0.01% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 0.01% (up 5.0% YoY) and the FY2025 annual result came in at 0.04%, up 23.0% from the prior year.
- Return on Sales fell to 0.01% in Q1 2026 per XLO's latest filing, from 0.01% in the prior quarter.
- Over five years, Return on Sales peaked at 0.0% in Q3 2025 and troughed at 0.08% in Q4 2024.
- A 3-year average of 0.04% and a median of 0.03% in 2025 frame the typical range for Return on Sales.
- The sharpest annual moves came in 2025 and 2026: Return on Sales grew 7 bps in 2025, then grew 4 bps in 2026.
- Over 3 years, Return on Sales stood at 0.08% in 2024, then surged by 89 bps to 0.01% in 2025, then retreated by 29 bps to 0.01% in 2026.
- According to Business Quant data, Return on Sales over the past three periods registered 0.01%, 0.01%, and 0.0% for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.97 Bn | 132.12 Bn | 2.84 Bn | 0.00% |
| 2 | Regeneron Pharmaceuticals | 86.64 Bn | 78.64 Bn | 3.93 Bn | 0.00% |
| 3 | Argenx Se | 65.55 Bn | 60.37 Bn | 1.37 Bn | 0.00% |
| 4 | Moderna | 61.26 Bn | 56.12 Bn | 52.00 Mn | -0.05% |
| 5 | BeOne Medicines | 42.30 Bn | 37.20 Bn | 1.53 Bn | 0.00% |
| 6 | Alnylam Pharmaceuticals | 31.66 Bn | 28.35 Bn | 992.69 Mn | 0.00% |
| 7 | BioNTech SE | 28.68 Bn | 10.29 Bn | 668.28 Mn | 0.00% |
| 8 | Insmed | 27.54 Bn | 26.38 Bn | 358.27 Mn | 0.00% |
| 9 | Royalty Pharma | 27.26 Bn | 26.42 Bn | - | 0.00% |
| 10 | Xilio Therapeutics | 176.87 Mn | 40.83 Mn | - | 0.00% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 0.00% |
| Mar 31, 2026 | -0.01% |
| Dec 31, 2025 | -0.01% |
| Sep 30, 2025 | 0.00% |
| Jun 30, 2025 | -0.02% |
| Mar 31, 2025 | -0.05% |
| Dec 31, 2024 | -0.08% |
| Sep 30, 2024 | -0.07% |
| Jun 30, 2024 | -0.06% |