Growth Metrics

Vertex Pharmaceuticals (VRTX) Return on Sales (2016 - 2025)

Vertex Pharmaceuticals (VRTX) has 17 years of Return on Sales data on record, last reported at 0.37% in Q4 2025.

  • For Q4 2025, Return on Sales rose 6.0% year-over-year to 0.37%; the TTM value through Dec 2025 reached 0.33%, up 38.0%, while the annual FY2025 figure was 0.33%, 38.0% up from the prior year.
  • Return on Sales reached 0.37% in Q4 2025 per VRTX's latest filing, up from 0.35% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.43% in Q3 2021 and bottomed at 1.36% in Q2 2024.
  • Average Return on Sales over 5 years is 0.26%, with a median of 0.37% recorded in 2022.
  • Peak YoY movement for Return on Sales: plummeted -173bps in 2024, then skyrocketed 171bps in 2025.
  • A 5-year view of Return on Sales shows it stood at 0.37% in 2021, then fell by -4bps to 0.36% in 2022, then grew by 8bps to 0.38% in 2023, then fell by -19bps to 0.31% in 2024, then rose by 19bps to 0.37% in 2025.
  • Per Business Quant database, its latest 3 readings for Return on Sales were 0.37% in Q4 2025, 0.35% in Q3 2025, and 0.35% in Q2 2025.