Growth Metrics

Alnylam Pharmaceuticals (ALNY) Return on Sales (2016 - 2025)

Alnylam Pharmaceuticals' Return on Sales history spans 17 years, with the latest figure at 0.1% for Q4 2025.

  • For Q4 2025, Return on Sales rose 24.0% year-over-year to 0.1%; the TTM value through Dec 2025 reached 0.1%, up 23.0%, while the annual FY2025 figure was 0.08%, 21.0% up from the prior year.
  • Return on Sales reached 0.1% in Q4 2025 per ALNY's latest filing, down from 0.23% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.23% in Q3 2025 to a low of 1.54% in Q3 2022.
  • Average Return on Sales over 5 years is 0.55%, with a median of 0.58% recorded in 2023.
  • Peak YoY movement for Return on Sales: soared 173bps in 2023, then plummeted -47bps in 2025.
  • A 5-year view of Return on Sales shows it stood at 1.0% in 2021, then surged by 38bps to 0.62% in 2022, then skyrocketed by 49bps to 0.31% in 2023, then surged by 55bps to 0.14% in 2024, then surged by 172bps to 0.1% in 2025.
  • Per Business Quant, the three most recent readings for ALNY's Return on Sales are 0.1% (Q4 2025), 0.23% (Q3 2025), and 0.09% (Q2 2025).