Xilio Therapeutics (XLO) Research & Development (2020 - 2026)

Xilio Therapeutics (XLO) reported Research & Development of $19.8 million for Q1 2026, up 139.92% on a YoY basis from $8.3 million in Q1 2025, and up 9.44% sequentially from $18.1 million in Q4 2025.

Xilio Therapeutics (XLO) Research & Development (2020 - 2026) Analysis & Trends

Xilio Therapeutics (XLO) has 7 years of Research & Development data on file, last reported at $19.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Research & Development rose 139.92% year-over-year to $19.8 million; the trailing twelve-month figure through Mar 2026 stood at $67.6 million (up 73.0% YoY), and the FY2025 full-year result was $56.0 million, up 35.98% from the prior year.
  • Research & Development grew to $19.8 million in Q1 2026, from $18.1 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $19.8 million in Q1 2026 to a low of $8.3 million in Q1 2025.
  • A 5-year average of $13.4 million and a median of $13.2 million in 2023 frame the typical range for Research & Development.
  • Across the five-year window, Research & Development sank 35.53% in 2024 and soared 139.92% in 2026, its largest moves.
  • Tracing XLO's Research & Development over 5 years: stood at $15.0 million in 2022, then slipped by 21.74% to $11.7 million in 2023, then declined by 24.71% to $8.8 million in 2024, then soared by 105.09% to $18.1 million in 2025, then rose by 9.44% to $19.8 million in 2026.
  • Business Quant data shows XLO's Research & Development at $19.8 million in Q1 2026, $18.1 million in Q4 2025, and $14.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Oculis Holding AG 66,981.90 Bn 66,981.62 Bn - -17.94 Mn
2 Nanobiotix 1,913.50 Bn 1,913.44 Bn - -
3 Akari Therapeutics 959.56 Bn 959.56 Bn - 1.46 Mn
4 BeOne Medicines 472.03 Bn 467.24 Bn 1.35 Bn 541.22 Mn
5 Vertex Pharmaceuticals 122.09 Bn 114.84 Bn 2.59 Bn 961.60 Mn
6 Regeneron Pharmaceuticals 70.01 Bn 61.26 Bn 3.31 Bn 1.54 Bn
7 Belite Bio 62.34 Bn 62.34 Bn - 15.66 Mn
8 Argenx Se 55.99 Bn 50.80 Bn 1.41 Bn 1.37 Bn
9 Alnylam Pharmaceuticals 37.49 Bn 34.48 Bn 959.66 Mn 364.87 Mn
10 Xilio Therapeutics 142.71 Mn -7.59 Mn - 19.83 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 19.83 Mn
Dec 31, 2025 18.12 Mn
Sep 30, 2025 14.32 Mn
Jun 30, 2025 15.33 Mn
Mar 31, 2025 8.27 Mn
Dec 31, 2024 8.84 Mn
Sep 30, 2024 10.76 Mn
Jun 30, 2024 11.22 Mn
Mar 31, 2024 10.40 Mn
Dec 31, 2023 11.74 Mn
Sep 30, 2023 11.05 Mn
Jun 30, 2023 13.22 Mn
Mar 31, 2023 16.13 Mn
Dec 31, 2022 15.00 Mn
Sep 30, 2022 13.04 Mn
Jun 30, 2022 16.25 Mn
Mar 31, 2022 14.92 Mn
Dec 31, 2021 11.35 Mn
Sep 30, 2021 10.47 Mn
Jun 30, 2021 17.75 Mn