Xilio Therapeutics (XLO) EV to CFO (2021 - 2026)
Xilio Therapeutics' (XLO) quarterly EV to CFO came in at 2.66 in Q2 2026, down 168.73% year-over-year from 3.87 in Q2 2025, and down 562.04% quarter-over-quarter from 0.58 in Q1 2026.
Analysis
Xilio Therapeutics (XLO) EV to CFO (2021 - 2026) Analysis & Trends
Xilio Therapeutics has disclosed EV to CFO across 6 years of filings, most recently posting 2.66 for Q2 2026.
- In Q2 2026, EV to CFO fell 168.73% year-over-year to 2.66; the TTM figure through Jun 2026 stood at 0.82 (down 119.59% YoY), while the FY2025 annual figure was 12.54, up 1888.15% from the prior year.
- EV to CFO came in at 2.66 for Q2 2026 at Xilio Therapeutics, down from 0.58 in the prior quarter.
- In the past five years, EV to CFO ranged from a high of 31.34 in Q4 2025 to a low of 2.66 in Q2 2026.
- Average EV to CFO over 5 years is 2.45, with a median of 0.47 recorded in 2024.
- Year-over-year, EV to CFO tumbled 611.55% in 2024 and jumped 3726.5% in 2025.
- Over 5 years, EV to CFO stood at 2.56 in 2022, then declined by 14.05% to 2.2 in 2023, then slumped by 62.75% to 0.82 in 2024, then jumped by 3726.5% to 31.34 in 2025, then slumped by 108.48% to 2.66 in 2026.
- Per Business Quant data, the three most recent EV to CFO figures were 2.66 in Q2 2026, 0.58 in Q1 2026, and 31.34 in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Amgen | 206.44 Bn | 192.45 Bn | 7.24 Bn |
| 2 | Gilead Sciences | 179.97 Bn | 176.79 Bn | 6.22 Bn |
| 3 | Vertex Pharmaceuticals | 130.57 Bn | 122.72 Bn | 2.84 Bn |
| 4 | Regeneron Pharmaceuticals | 81.63 Bn | 73.63 Bn | 3.93 Bn |
| 5 | Argenx Se | 60.34 Bn | 55.16 Bn | 1.37 Bn |
| 6 | Moderna | 54.37 Bn | 49.23 Bn | 52.00 Mn |
| 7 | Alnylam Pharmaceuticals | 33.07 Bn | 29.76 Bn | 992.69 Mn |
| 8 | Biogen | 31.84 Bn | 30.55 Bn | 1.96 Bn |
| 9 | Roivant Sciences | 29.49 Bn | 29.49 Bn | 1.16 Mn |
| 10 | Xilio Therapeutics | 174.55 Mn | 38.51 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -2.66 |
| Mar 31, 2026 | 0.58 |
| Dec 31, 2025 | 31.34 |
| Sep 30, 2025 | -1.01 |
| Jun 30, 2025 | 3.87 |
| Mar 31, 2025 | -1.21 |
| Dec 31, 2024 | 0.82 |
| Sep 30, 2024 | 0.82 |
| Jun 30, 2024 | -1.01 |
| Mar 31, 2024 | 0.37 |
| Dec 31, 2023 | 2.20 |
| Sep 30, 2023 | 0.13 |
| Jun 30, 2023 | 0.20 |
| Mar 31, 2023 | 0.25 |
| Dec 31, 2022 | 2.56 |
| Sep 30, 2022 | 2.98 |
| Jun 30, 2022 | 4.74 |
| Mar 31, 2022 | -0.80 |
| Dec 31, 2021 | 6.31 |