X4 Pharmaceuticals (XFOR) Operating Expenses (2017 - 2025)
X4 Pharmaceuticals (XFOR) posted Operating Expenses of $25.9 million for Q4 2025, down 10.44% on a QoQ basis from $28.9 million in Q3 2025, and down 29.7% year-over-year from $36.8 million in Q4 2024.
X4 Pharmaceuticals (XFOR) Operating Expenses (2017 - 2025) Analysis & Trends
X4 Pharmaceuticals' Operating Expenses history runs 9 years deep, the most recent figure standing at $25.9 million for Q4 2025.
- Quarterly Operating Expenses fell 29.7% year-over-year to $25.9 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $116.2 million (down 18.81% YoY) and the FY2025 annual result came in at $116.2 million, up 198.37% from the prior year.
- Operating Expenses was $25.9 million for Q4 2025 at X4 Pharmaceuticals, down from $28.9 million in the prior quarter.
- Across five years, Operating Expenses topped out at $37.3 million in Q1 2024 and bottomed at $17.9 million in Q1 2021.
- A 5-year average of $27.0 million and a median of $26.6 million in 2023 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2021 — Operating Expenses jumped 64.57% — and 2025, when it fell 29.7%.
- X4 Pharmaceuticals' Operating Expenses stood at $29.1 million in 2021, then slipped by 11.97% to $25.6 million in 2022, then fell by 1.48% to $25.2 million in 2023, then jumped by 46.22% to $36.8 million in 2024, then retreated by 29.7% to $25.9 million in 2025.
- Business Quant data shows XFOR's Operating Expenses at $25.9 million in Q4 2025, $28.9 million in Q3 2025, and $27.9 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,621.14 Bn | 66,620.85 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,915.18 Bn | 1,915.11 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.27 Bn | 466.48 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.81 Bn | 114.57 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 69.58 Bn | 60.82 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 62.72 Bn | 62.72 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 55.51 Bn | 50.33 Bn | 1.41 Bn | 2.89 Bn |
| 9 | Revolution Medicines | 37.35 Bn | 37.35 Bn | - | 445.22 Mn |
| 10 | X4 Pharmaceuticals | 167.90 Mn | -49.15 Mn | 2.20 Mn | 25.90 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 25.90 Mn |
| Sep 30, 2025 | 28.92 Mn |
| Jun 30, 2025 | 27.88 Mn |
| Mar 31, 2025 | 33.53 Mn |
| Dec 31, 2024 | 36.85 Mn |
| Sep 30, 2024 | 34.83 Mn |
| Jun 30, 2024 | 34.19 Mn |
| Mar 31, 2024 | 37.29 Mn |
| Dec 31, 2023 | 25.20 Mn |
| Sep 30, 2023 | 27.21 Mn |
| Jun 30, 2023 | 25.81 Mn |
| Mar 31, 2023 | 29.30 Mn |
| Dec 31, 2022 | 25.58 Mn |
| Sep 30, 2022 | 20.15 Mn |
| Jun 30, 2022 | 20.57 Mn |
| Mar 31, 2022 | 21.27 Mn |
| Dec 31, 2021 | 29.06 Mn |
| Sep 30, 2021 | 19.12 Mn |
| Jun 30, 2021 | 19.00 Mn |
| Mar 31, 2021 | 17.94 Mn |