X4 Pharmaceuticals (XFOR) Operating Expenses (2017 - 2025)
X4 Pharmaceuticals (XFOR) reported Operating Expenses of -$7.7 million for Q4 2025, down 121.02% on a YoY basis from $36.8 million in Q4 2024, and down 126.78% quarter-over-quarter from $28.9 million in Q3 2025.
X4 Pharmaceuticals (XFOR) Operating Expenses (2017 - 2025) Analysis & Trends
X4 Pharmaceuticals has reported Operating Expenses for 9 years, with the latest figure at -$7.7 million in Q4 2025.
- For the quarter ending Q4 2025, Operating Expenses fell 121.02% year-over-year to -$7.7 million; the trailing twelve-month figure through Dec 2025 stood at -$8.4 million (down 109.1% YoY), and the FY2025 full-year result was -$49.3 million, down 226.48% from the prior year.
- Operating Expenses for Q4 2025 stood at -$7.7 million, down from $28.9 million in the prior quarter.
- The five-year high for Operating Expenses was $37.3 million in Q1 2024, with the low at -$19.7 million in Q1 2025.
- Historically, Operating Expenses has averaged $18.2 million across 5 years, with a median of $23.2 million in 2022.
- Annual changes were most pronounced in 2024 — Operating Expenses tumbled 158.38% — and 2025, when it surged 282.05%.
- X4 Pharmaceuticals' Operating Expenses stood at $29.1 million in 2021, then retreated by 11.97% to $25.6 million in 2022, then dropped by 1.48% to $25.2 million in 2023, then surged by 46.22% to $36.8 million in 2024, then slumped by 121.02% to -$7.7 million in 2025.
- The last three Operating Expenses figures came in at -$7.7 million (Q4 2025), $28.9 million (Q3 2025), and -$9.9 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | 15.76 Mn |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | -67.40 Mn |
| 10 | X4 Pharmaceuticals | 156.06 Mn | 156.06 Mn | 2.20 Mn | -7.75 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -7.75 Mn |
| Sep 30, 2025 | 28.92 Mn |
| Jun 30, 2025 | -9.85 Mn |
| Mar 31, 2025 | -19.74 Mn |
| Dec 31, 2024 | 36.85 Mn |
| Sep 30, 2024 | -15.89 Mn |
| Jun 30, 2024 | 34.19 Mn |
| Mar 31, 2024 | 37.29 Mn |
| Dec 31, 2023 | 25.20 Mn |
| Sep 30, 2023 | 27.21 Mn |
| Jun 30, 2023 | 25.81 Mn |
| Mar 31, 2023 | 29.30 Mn |
| Dec 31, 2022 | 25.58 Mn |
| Sep 30, 2022 | 20.15 Mn |
| Jun 30, 2022 | 20.57 Mn |
| Mar 31, 2022 | 21.27 Mn |
| Dec 31, 2021 | 29.06 Mn |
| Sep 30, 2021 | 19.12 Mn |
| Jun 30, 2021 | 19.00 Mn |
| Mar 31, 2021 | 17.94 Mn |