X4 Pharmaceuticals (XFOR) Operating Expenses (2017 - 2025)

X4 Pharmaceuticals (XFOR) reported Operating Expenses of -$7.7 million for Q4 2025, down 121.02% on a YoY basis from $36.8 million in Q4 2024, and down 126.78% quarter-over-quarter from $28.9 million in Q3 2025.

X4 Pharmaceuticals (XFOR) Operating Expenses (2017 - 2025) Analysis & Trends

X4 Pharmaceuticals has reported Operating Expenses for 9 years, with the latest figure at -$7.7 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses fell 121.02% year-over-year to -$7.7 million; the trailing twelve-month figure through Dec 2025 stood at -$8.4 million (down 109.1% YoY), and the FY2025 full-year result was -$49.3 million, down 226.48% from the prior year.
  • Operating Expenses for Q4 2025 stood at -$7.7 million, down from $28.9 million in the prior quarter.
  • The five-year high for Operating Expenses was $37.3 million in Q1 2024, with the low at -$19.7 million in Q1 2025.
  • Historically, Operating Expenses has averaged $18.2 million across 5 years, with a median of $23.2 million in 2022.
  • Annual changes were most pronounced in 2024 — Operating Expenses tumbled 158.38% — and 2025, when it surged 282.05%.
  • X4 Pharmaceuticals' Operating Expenses stood at $29.1 million in 2021, then retreated by 11.97% to $25.6 million in 2022, then dropped by 1.48% to $25.2 million in 2023, then surged by 46.22% to $36.8 million in 2024, then slumped by 121.02% to -$7.7 million in 2025.
  • The last three Operating Expenses figures came in at -$7.7 million (Q4 2025), $28.9 million (Q3 2025), and -$9.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - 4.33 Mn
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - 32.68 Mn
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - 2.97 Mn
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - 15.76 Mn
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -3.82 Mn
7 Psyence Biomedical 251.43 Bn 251.42 Bn - 574,669.00
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 1.85 Bn
9 Abivax 94.37 Bn 94.37 Bn - -67.40 Mn
10 X4 Pharmaceuticals 156.06 Mn 156.06 Mn 2.20 Mn -7.75 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -7.75 Mn
Sep 30, 2025 28.92 Mn
Jun 30, 2025 -9.85 Mn
Mar 31, 2025 -19.74 Mn
Dec 31, 2024 36.85 Mn
Sep 30, 2024 -15.89 Mn
Jun 30, 2024 34.19 Mn
Mar 31, 2024 37.29 Mn
Dec 31, 2023 25.20 Mn
Sep 30, 2023 27.21 Mn
Jun 30, 2023 25.81 Mn
Mar 31, 2023 29.30 Mn
Dec 31, 2022 25.58 Mn
Sep 30, 2022 20.15 Mn
Jun 30, 2022 20.57 Mn
Mar 31, 2022 21.27 Mn
Dec 31, 2021 29.06 Mn
Sep 30, 2021 19.12 Mn
Jun 30, 2021 19.00 Mn
Mar 31, 2021 17.94 Mn