Growth Metrics

Trevi Therapeutics (TRVI) Operating Expenses (2018 - 2025)

Trevi Therapeutics' quarterly Operating Expenses came in at $10.2 million in Q4 2025, down 16.52% year-on-year from $12.2 million in Q4 2024, and down 26.56% quarter-over-quarter from $13.9 million in Q3 2025.

Trevi Therapeutics has reported Operating Expenses for 8 years, with the latest figure at $10.2 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses fell 16.52% year-over-year to $10.2 million; the trailing twelve-month figure through Mar 2026 stood at $37.9 million (down 4.44% YoY), and the FY2025 full-year result was $49.3 million, down 4.26% from the prior year.
  • Operating Expenses for Q4 2025 stood at $10.2 million, down from $13.9 million in the prior quarter.
  • The five-year high for Operating Expenses was $14.1 million in Q3 2024, with the low at $6.7 million in Q4 2022.
  • Average Operating Expenses over 5 years is $9.8 million, with a median of $8.9 million recorded in 2023.
  • Year-over-year, Operating Expenses dropped 19.53% in 2022 and soared 58.54% in 2024.
  • Tracing TRVI's Operating Expenses over 5 years: stood at $8.3 million in 2021, then dropped by 19.53% to $6.7 million in 2022, then jumped by 34.19% to $8.9 million in 2023, then jumped by 37.05% to $12.2 million in 2024, then dropped by 16.52% to $10.2 million in 2025.
  • The last three Operating Expenses figures came in at $10.2 million (Q4 2025), $13.9 million (Q3 2025), and $13.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Trevi Therapeutics 2.02 Bn 1.85 Bn - -

Historic Data

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DateValue
Dec 31, 2025 10.22 Mn
Sep 30, 2025 13.92 Mn
Jun 30, 2025 13.72 Mn
Dec 31, 2024 12.24 Mn
Sep 30, 2024 14.09 Mn
Jun 30, 2024 13.29 Mn
Mar 31, 2024 11.91 Mn
Dec 31, 2023 8.93 Mn
Sep 30, 2023 9.05 Mn
Jun 30, 2023 8.38 Mn
Mar 31, 2023 7.56 Mn
Dec 31, 2022 6.66 Mn
Sep 30, 2022 8.41 Mn
Jun 30, 2022 7.82 Mn
Mar 31, 2022 7.03 Mn
Dec 31, 2021 8.27 Mn
Sep 30, 2021 6.95 Mn
Jun 30, 2021 9.17 Mn
Mar 31, 2021 8.09 Mn
Dec 31, 2020 9.19 Mn
Sep 30, 2020 7.24 Mn
Jun 30, 2020 7.41 Mn
Mar 31, 2020 8.64 Mn
Dec 31, 2019 6.77 Mn
Sep 30, 2019 7.65 Mn
Jun 30, 2019 7.42 Mn
Mar 31, 2019 4.81 Mn
Dec 31, 2018 5.93 Mn
Sep 30, 2018 4.96 Mn
Jun 30, 2018 4.38 Mn
Mar 31, 2018 3.14 Mn