Vertex Pharmaceuticals (VRTX) Free Cash Flow (2009 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Free Cash Flow of $1.3 billion in Q1 2026, up 271.4% quarter-over-quarter from $348.6 million in Q4 2025, and up 66.37% on a YoY basis from $778.2 million in Q1 2025.

Vertex Pharmaceuticals (VRTX) Free Cash Flow (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Free Cash Flow history runs 18 years deep, the most recent figure standing at $1.3 billion for Q1 2026.

  • In Q1 2026, Free Cash Flow rose 66.37% year-over-year to $1.3 billion; the TTM figure through Mar 2026 stood at $3.7 billion (up 396.75% YoY), while the FY2025 annual figure was $3.2 billion, up 504.13% from the prior year.
  • Free Cash Flow was $1.3 billion for Q1 2026 at Vertex Pharmaceuticals, up from $348.6 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $1.3 billion in Q3 2024 to a low of -$3.8 billion in Q2 2024.
  • Historically, Free Cash Flow has averaged $644.7 million across 5 years, with a median of $927.4 million in 2025.
  • The sharpest annual moves came in 2022 and 2024: Free Cash Flow jumped 535.3% in 2022, then plunged 455.66% in 2024.
  • A 5-year view of Free Cash Flow shows it stood at $1.0 billion in 2022, then sank by 83.11% to $176.5 million in 2023, then surged by 178.75% to $492.0 million in 2024, then fell by 29.15% to $348.6 million in 2025, then soared by 271.4% to $1.3 billion in 2026.
  • The last three Free Cash Flow figures came in at $1.3 billion (Q1 2026), $348.6 million (Q4 2025), and $1.1 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -1.67 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -12.20 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.49 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.29 Bn
9 Abivax 91.96 Bn 91.96 Bn - 63,220.27
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn 848.30 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.29 Bn
Mar 31, 2026 1.29 Bn
Dec 31, 2025 348.60 Mn
Dec 31, 2025 348.60 Mn
Sep 30, 2025 1.14 Bn
Sep 30, 2025 1.14 Bn
Jun 30, 2025 927.40 Mn
Jun 30, 2025 927.40 Mn
Mar 31, 2025 778.20 Mn
Mar 31, 2025 778.20 Mn
Dec 31, 2024 492.00 Mn
Dec 31, 2024 492.00 Mn
Sep 30, 2024 1.30 Bn
Sep 30, 2024 1.30 Bn
Jun 30, 2024 -3.82 Bn
Jun 30, 2024 -3.82 Bn
Mar 31, 2024 1.24 Bn
Mar 31, 2024 1.24 Bn
Dec 31, 2023 176.50 Mn
Dec 31, 2023 176.50 Mn