Vertex Pharmaceuticals (VRTX) Free Cash Flow (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Free Cash Flow came in at $1.3 billion in Q1 2026, up 66.37% year-on-year from $778.2 million in Q1 2025, and up 271.4% quarter-over-quarter from $348.6 million in Q4 2025.

Vertex Pharmaceuticals (VRTX) Free Cash Flow (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Free Cash Flow history runs 18 years deep, the most recent figure standing at $1.3 billion for Q1 2026.

  • On a quarterly basis, Free Cash Flow rose 66.37% year-over-year to $1.3 billion in Q1 2026; TTM through Mar 2026 was $3.7 billion, a 396.75% increase from a year earlier, with the FY2025 full-year figure at $3.2 billion, up 504.13% from the prior year.
  • Free Cash Flow grew to $1.3 billion in Q1 2026 per VRTX's latest filing, from $348.6 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at $1.3 billion in Q3 2024 and bottomed at -$3.8 billion in Q2 2024.
  • The 5-year median for Free Cash Flow is $927.4 million (2025), against an average of $644.7 million.
  • Across the five-year window, Free Cash Flow soared 535.3% in 2022 and plunged 455.66% in 2024, its largest moves.
  • Year by year, Free Cash Flow stood at $1.0 billion in 2022, then tumbled by 83.11% to $176.5 million in 2023, then surged by 178.75% to $492.0 million in 2024, then fell by 29.15% to $348.6 million in 2025, then soared by 271.4% to $1.3 billion in 2026.
  • Per Business Quant, the three latest VRTX Free Cash Flow figures stand at $1.3 billion (Q1 2026), $348.6 million (Q4 2025), and $1.1 billion (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn 48.67 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.29 Bn
Mar 31, 2026 1.29 Bn
Dec 31, 2025 348.60 Mn
Dec 31, 2025 348.60 Mn
Sep 30, 2025 1.14 Bn
Sep 30, 2025 1.14 Bn
Jun 30, 2025 927.40 Mn
Jun 30, 2025 927.40 Mn
Mar 31, 2025 778.20 Mn
Mar 31, 2025 778.20 Mn
Dec 31, 2024 492.00 Mn
Dec 31, 2024 492.00 Mn
Sep 30, 2024 1.30 Bn
Sep 30, 2024 1.30 Bn
Jun 30, 2024 -3.82 Bn
Jun 30, 2024 -3.82 Bn
Mar 31, 2024 1.24 Bn
Mar 31, 2024 1.24 Bn
Dec 31, 2023 176.50 Mn
Dec 31, 2023 176.50 Mn