Growth Metrics

Vertex Pharmaceuticals (VRTX) FCF Margin (2009 - 2026)

Vertex Pharmaceuticals' quarterly FCF Margin came in at 43.35% in Q1 2026, up 1525.0% year-on-year from 2.67% in Q1 2025, and up 296.65% quarter-over-quarter from 10.93% in Q4 2025.

Vertex Pharmaceuticals has reported FCF Margin for 18 years, with the latest figure at 43.35% in Q1 2026.

  • For the quarter ending Q1 2026, FCF Margin rose 1525.0% year-over-year to 43.35%; the trailing twelve-month figure through Mar 2026 stood at 30.37% (up 4163.0% YoY), and the FY2025 full-year result was 26.61%, up 3378.0% from the prior year.
  • FCF Margin for Q1 2026 stood at 43.35%, up from 10.93% in the prior quarter.
  • The five-year high for FCF Margin was 49.47% in Q2 2022, with the low at 144.49% in Q2 2024.
  • Average FCF Margin over 5 years is 25.16%, with a median of 38.61% recorded in 2022.
  • Year-over-year, FCF Margin sank 18760 bps in 2024 and jumped 17577 bps in 2025.
  • Tracing VRTX's FCF Margin over 5 years: stood at 45.37% in 2022, then plunged by 85 bps to 7.01% in 2023, then surged by 141 bps to 16.9% in 2024, then tumbled by 35 bps to 10.93% in 2025, then soared by 297 bps to 43.35% in 2026.
  • The last three FCF Margin figures came in at 43.35% (Q1 2026), 10.93% (Q4 2025), and 37.04% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -3.98%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 43.35%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 23.53%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 4.17%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -

Historic Data

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DateValue
Mar 31, 2026 43.35%
Dec 31, 2025 10.93%
Sep 30, 2025 37.04%
Jun 30, 2025 31.28%
Mar 31, 2025 28.09%
Dec 31, 2024 16.90%
Sep 30, 2024 46.97%
Jun 30, 2024 -144.49%
Mar 31, 2024 46.02%
Dec 31, 2023 7.01%
Sep 30, 2023 49.44%
Jun 30, 2023 43.11%
Mar 31, 2023 36.12%
Dec 31, 2022 45.37%
Sep 30, 2022 38.61%
Jun 30, 2022 49.47%
Mar 31, 2022 42.56%
Dec 31, 2021 45.03%
Sep 30, 2021 44.09%
Jun 30, 2021 -13.92%
Mar 31, 2021 49.30%
Dec 31, 2020 27.27%
Sep 30, 2020 47.65%
Jun 30, 2020 66.95%
Mar 31, 2020 52.55%
Dec 31, 2019 275.53%
Sep 30, 2019 32.69%
Jun 30, 2019 47.53%
Mar 31, 2019 35.73%
Dec 31, 2018 34.36%
Sep 30, 2018 45.94%
Jun 30, 2018 38.83%
Mar 31, 2018 34.86%
Dec 31, 2017 28.32%
Sep 30, 2017 24.58%
Jun 30, 2017 30.19%
Mar 31, 2017 35.62%
Dec 31, 2016 28.33%
Sep 30, 2016 12.64%
Jun 30, 2016 5.86%
Mar 31, 2016 -6.81%
Dec 31, 2015 4.09%
Sep 30, 2015 -23.43%
Jun 30, 2015 -74.48%
Mar 31, 2015 -177.88%
Dec 31, 2014 -135.91%
Sep 30, 2014 -70.71%
Jun 30, 2014 -114.14%
Mar 31, 2014 -161.49%
Dec 31, 2013 4.10%
Sep 30, 2013 -14.54%
Jun 30, 2013 -1.07%
Mar 31, 2013 -25.09%
Dec 31, 2012 3.75%
Sep 30, 2012 25.17%
Jun 30, 2012 24.59%
Mar 31, 2012 -0.86%
Dec 31, 2011 87.75%
Sep 30, 2011 7.84%
Mar 31, 2011 -259.94%
Dec 31, 2010 -275.52%
Sep 30, 2010 -734.69%
Jun 30, 2010 -374.97%
Mar 31, 2010 -889.79%
Dec 31, 2009 -324.31%
Sep 30, 2009 -105.73%
Jun 30, 2009 -643.36%
Mar 31, 2009 -801.28%