Vertex Pharmaceuticals (VRTX) FCF Margin (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly FCF Margin came in at 43.35% in Q1 2026, up 1525.0% year-on-year from 2.67% in Q1 2025, and up 296.65% quarter-over-quarter from 10.93% in Q4 2025.

Vertex Pharmaceuticals (VRTX) FCF Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' FCF Margin history runs 18 years deep, the most recent figure standing at 43.35% for Q1 2026.

  • On a quarterly basis, FCF Margin rose 1525.0% year-over-year to 43.35% in Q1 2026; TTM through Mar 2026 was 30.37%, a 4163.0% increase from a year earlier, with the FY2025 full-year figure at 26.61%, up 3378.0% from the prior year.
  • FCF Margin climbed to 43.35% in Q1 2026 per VRTX's latest filing, from 10.93% in the prior quarter.
  • Across five years, FCF Margin topped out at 49.47% in Q2 2022 and bottomed at 144.49% in Q2 2024.
  • The 5-year median for FCF Margin is 38.61% (2022), against an average of 25.16%.
  • Across the five-year window, FCF Margin sank 18760 bps in 2024 and jumped 17577 bps in 2025, its largest moves.
  • Year by year, FCF Margin stood at 45.37% in 2022, then tumbled by 85 bps to 7.01% in 2023, then jumped by 141 bps to 16.9% in 2024, then slumped by 35 bps to 10.93% in 2025, then surged by 297 bps to 43.35% in 2026.
  • Per Business Quant, the three latest VRTX FCF Margin figures stand at 43.35% (Q1 2026), 10.93% (Q4 2025), and 37.04% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 10.45%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 43.35%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 23.53%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 4.17%

Historic Data

Download Data
DateValue
Mar 31, 2026 43.35%
Dec 31, 2025 10.93%
Sep 30, 2025 37.04%
Jun 30, 2025 31.28%
Mar 31, 2025 28.09%
Dec 31, 2024 16.90%
Sep 30, 2024 46.97%
Jun 30, 2024 -144.49%
Mar 31, 2024 46.02%
Dec 31, 2023 7.01%
Sep 30, 2023 49.44%
Jun 30, 2023 43.11%
Mar 31, 2023 36.12%
Dec 31, 2022 45.37%
Sep 30, 2022 38.61%
Jun 30, 2022 49.47%
Mar 31, 2022 42.56%
Dec 31, 2021 45.03%
Sep 30, 2021 44.09%
Jun 30, 2021 -13.92%