Sarepta Therapeutics (SRPT) Operating Expenses (2010 - 2026)

Sarepta Therapeutics (SRPT) recorded quarterly Operating Expenses of $372.4 million in Q1 2026, down 56.42% quarter-over-quarter from $854.5 million in Q4 2025, and down 64.37% on a YoY basis from $1.0 billion in Q1 2025.

Sarepta Therapeutics (SRPT) Operating Expenses (2010 - 2026) Analysis & Trends

Sarepta Therapeutics' Operating Expenses history runs 17 years deep, the most recent figure standing at $372.4 million for Q1 2026.

  • In Q1 2026, Operating Expenses fell 64.37% year-over-year to $372.4 million; the TTM figure through Mar 2026 stood at $2.2 billion (down 5.34% YoY), while the FY2025 annual figure was $2.9 billion, up 72.1% from the prior year.
  • Operating Expenses was $372.4 million for Q1 2026 at Sarepta Therapeutics, down from $854.5 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $1.0 billion in Q1 2025 to a low of $297.7 million in Q1 2022.
  • Historically, Operating Expenses has averaged $466.7 million across 5 years, with a median of $391.6 million in 2023.
  • The sharpest annual moves came in 2025 and 2026: Operating Expenses jumped 176.11% in 2025, then tumbled 64.37% in 2026.
  • A 5-year view of Operating Expenses shows it stood at $365.3 million in 2022, then advanced by 1.89% to $372.2 million in 2023, then soared by 33.47% to $496.7 million in 2024, then surged by 72.03% to $854.5 million in 2025, then plunged by 56.42% to $372.4 million in 2026.
  • The last three Operating Expenses figures came in at $372.4 million (Q1 2026), $854.5 million (Q4 2025), and $502.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.33 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -138.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 574,669.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.96 Bn 91.96 Bn - -67.40 Mn
10 Sarepta Therapeutics 1.84 Bn 1.16 Bn 291.52 Mn 372.37 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 372.37 Mn
Dec 31, 2025 854.52 Mn
Sep 30, 2025 502.75 Mn
Jun 30, 2025 495.51 Mn
Mar 31, 2025 1.05 Bn
Dec 31, 2024 496.73 Mn
Sep 30, 2024 444.98 Mn
Jun 30, 2024 363.63 Mn
Mar 31, 2024 378.56 Mn
Dec 31, 2023 372.16 Mn
Sep 30, 2023 352.66 Mn
Jun 30, 2023 394.76 Mn
Mar 31, 2023 391.59 Mn
Dec 31, 2022 365.26 Mn
Sep 30, 2022 361.62 Mn
Jun 30, 2022 444.62 Mn
Mar 31, 2022 297.71 Mn
Dec 31, 2021 307.27 Mn
Sep 30, 2021 223.86 Mn
Jun 30, 2021 331.66 Mn