Sarepta Therapeutics (SRPT) Operating Expenses (2010 - 2026)

Sarepta Therapeutics' (SRPT) quarterly Operating Expenses came in at $372.4 million in Q1 2026, down 64.37% year-on-year from $1.0 billion in Q1 2025, and down 56.42% quarter-over-quarter from $854.5 million in Q4 2025.

Sarepta Therapeutics (SRPT) Operating Expenses (2010 - 2026) Analysis & Trends

Sarepta Therapeutics' Operating Expenses history runs 17 years deep, the most recent figure standing at $372.4 million for Q1 2026.

  • On a quarterly basis, Operating Expenses fell 64.37% year-over-year to $372.4 million in Q1 2026; TTM through Mar 2026 was $2.2 billion, a 5.34% decrease from a year earlier, with the FY2025 full-year figure at $2.9 billion, up 72.1% from the prior year.
  • Operating Expenses eased to $372.4 million in Q1 2026 per SRPT's latest filing, from $854.5 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $1.0 billion in Q1 2025 and bottomed at $297.7 million in Q1 2022.
  • The 5-year median for Operating Expenses is $391.6 million (2023), against an average of $466.7 million.
  • Across the five-year window, Operating Expenses soared 176.11% in 2025 and tumbled 64.37% in 2026, its largest moves.
  • Year by year, Operating Expenses stood at $365.3 million in 2022, then advanced by 1.89% to $372.2 million in 2023, then soared by 33.47% to $496.7 million in 2024, then surged by 72.03% to $854.5 million in 2025, then slumped by 56.42% to $372.4 million in 2026.
  • Per Business Quant, the three latest SRPT Operating Expenses figures stand at $372.4 million (Q1 2026), $854.5 million (Q4 2025), and $502.7 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Sarepta Therapeutics 1.69 Bn 1.28 Bn 622.04 Mn 372.37 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 372.37 Mn
Dec 31, 2025 854.52 Mn
Sep 30, 2025 502.75 Mn
Jun 30, 2025 495.51 Mn
Mar 31, 2025 1.05 Bn
Dec 31, 2024 496.73 Mn
Sep 30, 2024 444.98 Mn
Jun 30, 2024 363.63 Mn
Mar 31, 2024 378.56 Mn
Dec 31, 2023 372.16 Mn
Sep 30, 2023 352.66 Mn
Jun 30, 2023 394.76 Mn
Mar 31, 2023 391.59 Mn
Dec 31, 2022 365.26 Mn
Sep 30, 2022 361.62 Mn
Jun 30, 2022 444.62 Mn
Mar 31, 2022 297.71 Mn
Dec 31, 2021 307.27 Mn
Sep 30, 2021 223.86 Mn
Jun 30, 2021 331.66 Mn