Spero Therapeutics (SPRO) Return on Assets [ROA] (2017 - 2026)
Spero Therapeutics (SPRO) recorded Return on Assets [ROA] of 13.23% in Q2 2026, up 89.96 percentage points from -76.73% a year earlier but down 10.60 percentage points from the prior quarter.
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Analysis
Spero Therapeutics (SPRO) Return on Assets [ROA] (2017 - 2026) Analysis & Trends
For FY2025, Spero Therapeutics reported Return on Assets [ROA] of 9.58%, up 56.42 percentage points from FY2024.
- Annual Return on Assets [ROA] has a five-year change of +69.90 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Assets [ROA] came in at -46.84% in FY2024 (-61.68 pp), 14.85% in FY2023 (+46.22 pp), -31.37% in FY2022 (+23.97 pp) and -55.34% in FY2021 (+4.98 pp).
- Quarterly Return on Assets [ROA] has ranged from -159.98% in Q3 2022 to 23.83% in Q1 2026 over the past five years.
- On a year-over-year basis, Return on Assets [ROA] has increased for three consecutive quarters, with an average year-over-year change of -7.88 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Assets [ROA] in the last five years was a gain of 158.41 percentage points in Q3 2023, against a drop of 100.12 percentage points in Q3 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at 23.83% (Q1 2026), 13.89% (Q4 2025) and -75.50% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,162.99 Bn | 1,131.58 Bn | 19.71 Bn | 20.64% |
| 2 | Johnson & Johnson | 633.71 Bn | 552.23 Bn | 17.26 Bn | 10.47% |
| 3 | AbbVie | 502.40 Bn | 475.51 Bn | 12.70 Bn | 4.65% |
| 4 | Merck | 376.48 Bn | 330.86 Bn | 12.21 Bn | 2.45% |
| 5 | Novartis Ag | 303.61 Bn | 267.60 Bn | 11.24 Bn | 10.60% |
| 6 | Astrazeneca | 267.02 Bn | 240.70 Bn | 12.86 Bn | 9.10% |
| 7 | Amgen | 240.85 Bn | 196.25 Bn | 7.24 Bn | 9.29% |
| 8 | Gilead Sciences | 193.39 Bn | 167.58 Bn | 6.22 Bn | -6.13% |
| 9 | Pfizer | 172.14 Bn | 118.78 Bn | 10.94 Bn | 2.14% |
| 10 | Spero Therapeutics | 67.24 Mn | -128.54 Mn | - | 13.23% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 13.23% |
| Mar 31, 2026 | 23.83% |
| Dec 31, 2025 | 13.89% |
| Sep 30, 2025 | -75.50% |
| Jun 30, 2025 | -76.73% |
| Mar 31, 2025 | -74.21% |
| Dec 31, 2024 | -55.88% |
| Sep 30, 2024 | 2.43% |
| Jun 30, 2024 | 10.96% |
| Mar 31, 2024 | 13.36% |
| Dec 31, 2023 | 15.77% |
| Sep 30, 2023 | -1.57% |
| Jun 30, 2023 | -9.54% |
| Mar 31, 2023 | -22.63% |
| Dec 31, 2022 | -49.04% |
| Sep 30, 2022 | -159.98% |
| Jun 30, 2022 | -108.20% |
| Mar 31, 2022 | -65.13% |
| Dec 31, 2021 | -56.88% |
| Sep 30, 2021 | -59.86% |
API Access
Spero Therapeutics Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=SPRO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();