Spero Therapeutics (SPRO) Price to Book (2017 - 2026)
Spero Therapeutics' Price to Book came in at 2.91 for Q2 2026, down 41.4% from 4.96 a year earlier but up 13.6% from the prior quarter.
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Analysis
Spero Therapeutics (SPRO) Price to Book (2017 - 2026) Analysis & Trends
For FY2025, Spero Therapeutics' Price to Book was 2.23, up 82.7% from FY2024.
- Going back by year, Price to Book was 1.22 in FY2024 (+67.3%), 0.73 in FY2023 (-14.9%), 0.86 in FY2022 (-85.4%) and 5.87 in FY2021 (+78.7%).
- The five-year range for quarterly Price to Book is 0.72 (Q2 2022) to 5.87 (Q4 2021).
- Year-over-year, Price to Book increased in six of the last eight quarters, with growth averaging 121.1%.
- The fastest year-over-year change in Price to Book over five years came in Q2 2025 (growth of 469.1%), and the weakest in Q4 2022 (a decline of 85.4%).
- Business Quant data shows SPRO's Price to Book at 2.56 (Q1 2026), 2.23 (Q4 2025) and 4.00 (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn |
| 10 | Spero Therapeutics | 68.40 Mn | -127.38 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 2.91 |
| Mar 31, 2026 | 2.56 |
| Dec 31, 2025 | 2.23 |
| Sep 30, 2025 | 4.00 |
| Jun 30, 2025 | 4.96 |
| Mar 31, 2025 | 1.19 |
| Dec 31, 2024 | 1.22 |
| Sep 30, 2024 | 1.11 |
| Jun 30, 2024 | 0.87 |
| Mar 31, 2024 | 0.96 |
| Dec 31, 2023 | 0.73 |
| Sep 30, 2023 | 1.19 |
| Jun 30, 2023 | 1.39 |
| Mar 31, 2023 | 1.18 |
| Dec 31, 2022 | 0.86 |
| Sep 30, 2022 | 2.64 |
| Jun 30, 2022 | 0.72 |
| Mar 31, 2022 | 4.56 |
| Dec 31, 2021 | 5.87 |
| Sep 30, 2021 | 5.30 |
API Access
Spero Therapeutics Price to Book API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=price-to-book&ticker=SPRO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "price-to-book", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=price-to-book&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();