Vertex Pharmaceuticals (VRTX) EBT Margin (2009 - 2026)

Vertex Pharmaceuticals (VRTX) posted quarterly EBT Margin of 41.95% for Q1 2026, up 1558.0% year-over-year from 2.53% in Q1 2025, and up 0.53% quarter-over-quarter from 41.72% in Q4 2025.

Vertex Pharmaceuticals (VRTX) EBT Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' EBT Margin history runs 18 years deep, the most recent figure standing at 41.95% for Q1 2026.

  • In Q1 2026, EBT Margin rose 1558.0% year-over-year to 41.95%; the TTM figure through Mar 2026 stood at 42.28% (up 4498.0% YoY), while the FY2025 annual figure was 38.69%, up 3643.0% from the prior year.
  • EBT Margin for Q1 2026 stood at 41.95%, up from 41.72% in the prior quarter.
  • The five-year high for EBT Margin was 50.4% in Q3 2022, with the low at 128.18% in Q2 2024.
  • The 5-year median for EBT Margin is 44.16% (2024), against an average of 33.21%.
  • The sharpest annual moves came in 2024 and 2025: EBT Margin tumbled 17477 bps in 2024, then jumped 17146 bps in 2025.
  • Vertex Pharmaceuticals' EBT Margin stood at 46.76% in 2022, then fell by 3 bps to 45.58% in 2023, then dropped by 14 bps to 39.03% in 2024, then climbed by 7 bps to 41.72% in 2025, then gained by 1 bps to 41.95% in 2026.
  • Business Quant data shows VRTX's EBT Margin at 41.95% in Q1 2026, 41.72% in Q4 2025, and 42.22% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 41.75%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 35.61%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 34.77%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 18.33%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -94.22%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 13.77%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -2.67%
10 Roivant Sciences 26.16 Bn 26.85 Bn 1.16 Mn -20,427.46%

Historic Data

Download Data
DateValue
Jun 30, 2026 41.75%
Mar 31, 2026 41.95%
Dec 31, 2025 41.72%
Sep 30, 2025 42.22%
Jun 30, 2025 43.28%
Mar 31, 2025 26.37%
Dec 31, 2024 39.03%
Sep 30, 2024 44.16%
Jun 30, 2024 -128.18%
Mar 31, 2024 47.54%
Dec 31, 2023 45.58%
Sep 30, 2023 47.48%
Jun 30, 2023 46.59%
Mar 31, 2023 37.54%
Dec 31, 2022 46.76%
Sep 30, 2022 50.40%
Jun 30, 2022 46.64%
Mar 31, 2022 45.52%
Dec 31, 2021 42.02%
Sep 30, 2021 54.57%