Vertex Pharmaceuticals (VRTX) EBT Margin (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly EBT Margin came in at 41.95% in Q1 2026, up 1558.0% year-on-year from 2.53% in Q1 2025, and up 0.53% quarter-over-quarter from 41.72% in Q4 2025.

Vertex Pharmaceuticals (VRTX) EBT Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' EBT Margin history runs 18 years deep, the most recent figure standing at 41.95% for Q1 2026.

  • On a quarterly basis, EBT Margin rose 1558.0% year-over-year to 41.95% in Q1 2026; TTM through Mar 2026 was 42.28%, a 4498.0% increase from a year earlier, with the FY2025 full-year figure at 38.69%, up 3643.0% from the prior year.
  • EBT Margin improved to 41.95% in Q1 2026 per VRTX's latest filing, from 41.72% in the prior quarter.
  • Across five years, EBT Margin topped out at 50.4% in Q3 2022 and bottomed at 128.18% in Q2 2024.
  • The 5-year median for EBT Margin is 44.16% (2024), against an average of 33.21%.
  • Across the five-year window, EBT Margin plunged 17477 bps in 2024 and jumped 17146 bps in 2025, its largest moves.
  • Year by year, EBT Margin stood at 46.76% in 2022, then retreated by 3 bps to 45.58% in 2023, then declined by 14 bps to 39.03% in 2024, then grew by 7 bps to 41.72% in 2025, then advanced by 1 bps to 41.95% in 2026.
  • Per Business Quant, the three latest VRTX EBT Margin figures stand at 41.95% (Q1 2026), 41.72% (Q4 2025), and 42.22% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 17.13%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 41.95%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 23.05%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 33.74%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 18.99%

Historic Data

Download Data
DateValue
Mar 31, 2026 41.95%
Dec 31, 2025 41.72%
Sep 30, 2025 42.22%
Jun 30, 2025 43.28%
Mar 31, 2025 26.37%
Dec 31, 2024 39.03%
Sep 30, 2024 44.16%
Jun 30, 2024 -128.18%
Mar 31, 2024 47.54%
Dec 31, 2023 45.58%
Sep 30, 2023 47.48%
Jun 30, 2023 46.59%
Mar 31, 2023 37.54%
Dec 31, 2022 46.76%
Sep 30, 2022 50.40%
Jun 30, 2022 46.64%
Mar 31, 2022 45.52%
Dec 31, 2021 42.02%
Sep 30, 2021 54.57%
Jun 30, 2021 -2.46%