Senti Biosciences (SNTI) Operating Expenses (2021 - 2025)

Senti Biosciences' quarterly Operating Expenses came in at $18.7 million in Q4 2025, up 15.41% year-on-year from $16.2 million in Q4 2024, and up 10.09% quarter-over-quarter from $16.9 million in Q3 2025.

Senti Biosciences has reported Operating Expenses for 5 years, with the latest figure at $18.7 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses rose 15.41% year-over-year to $18.7 million; the trailing twelve-month figure through Dec 2025 stood at $68.8 million (up 12.72% YoY), and the FY2025 full-year result was $68.8 million, up 12.72% from the prior year.
  • Operating Expenses for Q4 2025 stood at $18.7 million, up from $16.9 million in the prior quarter.
  • The five-year high for Operating Expenses was $44.2 million in Q3 2023, with the low at $1178.0 in Q1 2021.
  • Average Operating Expenses over 5 years is $16.4 million, with a median of $16.3 million recorded in 2023.
  • Year-over-year, Operating Expenses jumped 1091750.59% in 2022 and plunged 65.59% in 2024.
  • Tracing SNTI's Operating Expenses over 5 years: stood at $11.7 million in 2021, then jumped by 44.31% to $16.9 million in 2022, then gained by 10.95% to $18.7 million in 2023, then slipped by 13.54% to $16.2 million in 2024, then advanced by 15.41% to $18.7 million in 2025.
  • The last three Operating Expenses figures came in at $18.7 million (Q4 2025), $16.9 million (Q3 2025), and $16.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Senti Biosciences Holdings 22.25 Mn 22.25 Mn - -

Historic Data

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DateValue
Dec 31, 2025 18.66 Mn
Sep 30, 2025 16.95 Mn
Jun 30, 2025 16.80 Mn
Mar 31, 2025 16.40 Mn
Dec 31, 2024 16.17 Mn
Sep 30, 2024 15.22 Mn
Jun 30, 2024 13.36 Mn
Mar 31, 2024 16.30 Mn
Dec 31, 2023 18.70 Mn
Sep 30, 2023 44.21 Mn
Jun 30, 2023 16.13 Mn
Mar 31, 2023 16.25 Mn
Dec 31, 2022 16.85 Mn
Sep 30, 2022 16.51 Mn
Jun 30, 2022 23.13 Mn
Mar 31, 2022 12.86 Mn
Dec 31, 2021 11.68 Mn
Sep 30, 2021 12.53 Mn
Jun 30, 2021 9.79 Mn
Mar 31, 2021 1,178.00