Senti Biosciences Holdings SNTI
NASDAQ SNTI
$0.41 -0.02 (-4.86%)
As of: Aug 21, 2026 · 11:15 AM EDT

Senti Biosciences Holdings (SNTI) Operating Expenses (2021 - 2025)

Senti Biosciences Holdings (SNTI) posted quarterly Operating Expenses of $18.7 million for Q4 2025, up 15.41% year-over-year from $16.2 million in Q4 2024, and up 10.09% quarter-over-quarter from $16.9 million in Q3 2025.

Senti Biosciences Holdings (SNTI) Operating Expenses (2021 - 2025) Analysis & Trends

Senti Biosciences Holdings' Operating Expenses history runs 5 years deep, the most recent figure standing at $18.7 million for Q4 2025.

  • In Q4 2025, Operating Expenses rose 15.41% year-over-year to $18.7 million; the TTM figure through Dec 2025 stood at $68.8 million (up 12.72% YoY), while the FY2025 annual figure was $68.8 million, up 12.72% from the prior year.
  • Operating Expenses for Q4 2025 stood at $18.7 million, up from $16.9 million in the prior quarter.
  • The five-year high for Operating Expenses was $44.2 million in Q3 2023, with the low at $1178.0 in Q1 2021.
  • The 5-year median for Operating Expenses is $16.3 million (2023), against an average of $16.4 million.
  • The sharpest annual moves came in 2022 and 2024: Operating Expenses jumped 1091750.59% in 2022, then tumbled 65.59% in 2024.
  • Senti Biosciences Holdings' Operating Expenses stood at $11.7 million in 2021, then surged by 44.31% to $16.9 million in 2022, then increased by 10.95% to $18.7 million in 2023, then retreated by 13.54% to $16.2 million in 2024, then rose by 15.41% to $18.7 million in 2025.
  • Business Quant data shows SNTI's Operating Expenses at $18.7 million in Q4 2025, $16.9 million in Q3 2025, and $16.8 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 139.99 Bn 132.14 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 86.80 Bn 78.80 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 65.38 Bn 60.19 Bn 1.37 Bn 2.89 Bn
4 Moderna 60.70 Bn 55.56 Bn 52.00 Mn 960.00 Mn
5 BeOne Medicines 42.22 Bn 37.12 Bn 1.53 Bn 1.21 Bn
6 Alnylam Pharmaceuticals 31.67 Bn 28.36 Bn 992.69 Mn 1.06 Bn
7 BioNTech SE 28.45 Bn 10.06 Bn 668.28 Mn -784.57 Mn
8 Insmed 27.47 Bn 26.31 Bn 358.27 Mn 427.03 Mn
9 Royalty Pharma 27.21 Bn 26.37 Bn - 541.02 Mn
10 Senti Biosciences Holdings 12.92 Mn 12.92 Mn - 14.51 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 18.66 Mn
Sep 30, 2025 16.95 Mn
Jun 30, 2025 16.80 Mn
Mar 31, 2025 16.40 Mn
Dec 31, 2024 16.17 Mn
Sep 30, 2024 15.22 Mn
Jun 30, 2024 13.36 Mn
Mar 31, 2024 16.30 Mn
Dec 31, 2023 18.70 Mn
Sep 30, 2023 44.21 Mn
Jun 30, 2023 16.13 Mn
Mar 31, 2023 16.25 Mn
Dec 31, 2022 16.85 Mn
Sep 30, 2022 16.51 Mn
Jun 30, 2022 23.13 Mn
Mar 31, 2022 12.86 Mn
Dec 31, 2021 11.68 Mn
Sep 30, 2021 12.53 Mn
Jun 30, 2021 9.79 Mn
Mar 31, 2021 1,178.00