Alnylam Pharmaceuticals (ALNY) Operating Income (2009 - 2026)
Alnylam Pharmaceuticals' (ALNY) quarterly Operating Income came in at $231.4 million in Q2 2026, up 1528.74% on a YoY basis from $14.2 million in Q2 2025, and down 13.85% quarter-over-quarter from $268.6 million in Q1 2026.
Analysis
Alnylam Pharmaceuticals (ALNY) Operating Income (2009 - 2026) Analysis & Trends
Alnylam Pharmaceuticals (ALNY) has reported Operating Income for 18 consecutive years, with $231.4 million the latest figure, recorded in Q2 2026.
- For the quarter ending Q2 2026, Operating Income rose 1528.74% year-over-year to $231.4 million; the trailing twelve-month figure through Jun 2026 stood at $999.8 million (up 654.86% YoY), and the FY2025 full-year result was $501.6 million, up 383.56% from the prior year.
- Operating Income eased to $231.4 million in Q2 2026 per ALNY's latest filing, from $268.6 million in the prior quarter.
- Across five years, Operating Income topped out at $368.0 million in Q3 2025 and bottomed at -$258.0 million in Q3 2022.
- Historically, Operating Income has averaged -$13.5 million across 5 years, with a median of -$60.2 million in 2024.
- The sharpest annual moves came in 2024 and 2026: Operating Income slumped 135.96% in 2024, then jumped 1528.74% in 2026.
- Over 5 years, Operating Income stood at -$188.6 million in 2022, then soared by 38.28% to -$116.4 million in 2023, then increased by 9.66% to -$105.2 million in 2024, then surged by 225.26% to $131.7 million in 2025, then soared by 75.71% to $231.4 million in 2026.
- According to Business Quant data, Operating Income over the past three periods registered $231.4 million, $268.6 million, and $131.7 million for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 236.37 Bn | 222.38 Bn | 7.24 Bn | 3.51 Bn |
| 2 | Gilead Sciences | 187.38 Bn | 184.12 Bn | 6.22 Bn | -10.39 Bn |
| 3 | Vertex Pharmaceuticals | 138.36 Bn | 130.51 Bn | 2.84 Bn | 1.25 Bn |
| 4 | Regeneron Pharmaceuticals | 85.09 Bn | 77.10 Bn | 3.93 Bn | 1.29 Bn |
| 5 | Argenx Se | 63.93 Bn | 58.75 Bn | 1.37 Bn | 493.00 Mn |
| 6 | Moderna | 58.07 Bn | 52.94 Bn | 52.00 Mn | -815.00 Mn |
| 7 | Alnylam Pharmaceuticals | 35.59 Bn | 32.28 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Biogen | 32.63 Bn | 31.34 Bn | 1.96 Bn | -644.50 Mn |
| 9 | Insmed | 27.57 Bn | 26.41 Bn | 358.27 Mn | -1.55 Mn |
| 10 | BioNTech SE | 26.24 Bn | 12.58 Bn | 10.00 Mn | -1.10 Bn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 231.44 Mn |
| Mar 31, 2026 | 268.64 Mn |
| Dec 31, 2025 | 131.72 Mn |
| Sep 30, 2025 | 367.98 Mn |
| Jun 30, 2025 | -16.20 Mn |
| Mar 31, 2025 | 18.08 Mn |
| Dec 31, 2024 | -105.16 Mn |
| Sep 30, 2024 | -76.91 Mn |
| Jun 30, 2024 | 48.61 Mn |
| Mar 31, 2024 | -43.44 Mn |
| Dec 31, 2023 | -116.40 Mn |
| Sep 30, 2023 | 213.87 Mn |
| Jun 30, 2023 | -229.83 Mn |
| Mar 31, 2023 | -149.81 Mn |
| Dec 31, 2022 | -188.61 Mn |
| Sep 30, 2022 | -258.04 Mn |
| Jun 30, 2022 | -191.69 Mn |
| Mar 31, 2022 | -146.73 Mn |
| Dec 31, 2021 | -194.56 Mn |
| Sep 30, 2021 | -181.68 Mn |