Alnylam Pharmaceuticals ALNY
NASDAQ ALNY
$266.11 +1.61 (+0.61%)
At close: Sep 4, 2026 · 4:00 PM EDT

Alnylam Pharmaceuticals (ALNY) Operating Income (2009 - 2026)

Alnylam Pharmaceuticals' (ALNY) quarterly Operating Income came in at $231.4 million in Q2 2026, up 1528.74% on a YoY basis from $14.2 million in Q2 2025, and down 13.85% quarter-over-quarter from $268.6 million in Q1 2026.

Analysis

Alnylam Pharmaceuticals (ALNY) Operating Income (2009 - 2026) Analysis & Trends

Alnylam Pharmaceuticals (ALNY) has reported Operating Income for 18 consecutive years, with $231.4 million the latest figure, recorded in Q2 2026.

  • For the quarter ending Q2 2026, Operating Income rose 1528.74% year-over-year to $231.4 million; the trailing twelve-month figure through Jun 2026 stood at $999.8 million (up 654.86% YoY), and the FY2025 full-year result was $501.6 million, up 383.56% from the prior year.
  • Operating Income eased to $231.4 million in Q2 2026 per ALNY's latest filing, from $268.6 million in the prior quarter.
  • Across five years, Operating Income topped out at $368.0 million in Q3 2025 and bottomed at -$258.0 million in Q3 2022.
  • Historically, Operating Income has averaged -$13.5 million across 5 years, with a median of -$60.2 million in 2024.
  • The sharpest annual moves came in 2024 and 2026: Operating Income slumped 135.96% in 2024, then jumped 1528.74% in 2026.
  • Over 5 years, Operating Income stood at -$188.6 million in 2022, then soared by 38.28% to -$116.4 million in 2023, then increased by 9.66% to -$105.2 million in 2024, then surged by 225.26% to $131.7 million in 2025, then soared by 75.71% to $231.4 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered $231.4 million, $268.6 million, and $131.7 million for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Amgen 236.37 Bn 222.38 Bn 7.24 Bn 3.51 Bn
2 Gilead Sciences 187.38 Bn 184.12 Bn 6.22 Bn -10.39 Bn
3 Vertex Pharmaceuticals 138.36 Bn 130.51 Bn 2.84 Bn 1.25 Bn
4 Regeneron Pharmaceuticals 85.09 Bn 77.10 Bn 3.93 Bn 1.29 Bn
5 Argenx Se 63.93 Bn 58.75 Bn 1.37 Bn 493.00 Mn
6 Moderna 58.07 Bn 52.94 Bn 52.00 Mn -815.00 Mn
7 Alnylam Pharmaceuticals 35.59 Bn 32.28 Bn 992.69 Mn 231.44 Mn
8 Biogen 32.63 Bn 31.34 Bn 1.96 Bn -644.50 Mn
9 Insmed 27.57 Bn 26.41 Bn 358.27 Mn -1.55 Mn
10 BioNTech SE 26.24 Bn 12.58 Bn 10.00 Mn -1.10 Bn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 231.44 Mn
Mar 31, 2026 268.64 Mn
Dec 31, 2025 131.72 Mn
Sep 30, 2025 367.98 Mn
Jun 30, 2025 -16.20 Mn
Mar 31, 2025 18.08 Mn
Dec 31, 2024 -105.16 Mn
Sep 30, 2024 -76.91 Mn
Jun 30, 2024 48.61 Mn
Mar 31, 2024 -43.44 Mn
Dec 31, 2023 -116.40 Mn
Sep 30, 2023 213.87 Mn
Jun 30, 2023 -229.83 Mn
Mar 31, 2023 -149.81 Mn
Dec 31, 2022 -188.61 Mn
Sep 30, 2022 -258.04 Mn
Jun 30, 2022 -191.69 Mn
Mar 31, 2022 -146.73 Mn
Dec 31, 2021 -194.56 Mn
Sep 30, 2021 -181.68 Mn