Revolution Medicines (RVMD) Operating Income (2019 - 2026)

Revolution Medicines' (RVMD) quarterly Operating Income came in at -$445.2 million in Q1 2026, down 84.92% year-on-year from -$3.0 billion in Q1 2025, and down 23.12% quarter-over-quarter from -$361.6 million in Q4 2025.

Revolution Medicines (RVMD) Operating Income (2019 - 2026) Analysis & Trends

Revolution Medicines' Operating Income history runs 8 years deep, the most recent figure standing at -$445.2 million for Q1 2026.

  • On a quarterly basis, Operating Income fell 84.92% year-over-year to -$445.2 million in Q1 2026; TTM through Mar 2026 was -$1.4 billion, a 75.68% decrease from a year earlier, with the FY2025 full-year figure at -$1.2 billion, down 71.48% from the prior year.
  • Operating Income slipped to -$445.2 million in Q1 2026 per RVMD's latest filing, from -$361.6 million in the prior quarter.
  • Across five years, Operating Income topped out at -$57.9 million in Q1 2022 and bottomed at -$445.2 million in Q1 2026.
  • The 5-year median for Operating Income is -$156.6 million (2024), against an average of -$180.2 million.
  • Across the five-year window, Operating Income decreased 16.62% in 2022 and plunged 191.67% in 2023, its largest moves.
  • Year by year, Operating Income stood at -$61.7 million in 2022, then plunged by 191.67% to -$180.0 million in 2023, then dropped by 20.18% to -$216.3 million in 2024, then slumped by 67.18% to -$361.6 million in 2025, then retreated by 23.12% to -$445.2 million in 2026.
  • Per Business Quant, the three latest RVMD Operating Income figures stand at -$445.2 million (Q1 2026), -$361.6 million (Q4 2025), and -$315.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 268.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -445.22 Mn
Dec 31, 2025 -361.63 Mn
Sep 30, 2025 -315.27 Mn
Jun 30, 2025 -264.71 Mn
Mar 31, 2025 -240.76 Mn
Dec 31, 2024 -216.31 Mn
Sep 30, 2024 -175.71 Mn
Jun 30, 2024 -156.64 Mn
Mar 31, 2024 -140.86 Mn
Dec 31, 2023 -179.98 Mn
Sep 30, 2023 -123.25 Mn
Jun 30, 2023 -108.80 Mn
Mar 31, 2023 -75.16 Mn
Dec 31, 2022 -61.71 Mn
Sep 30, 2022 -76.53 Mn
Jun 30, 2022 -62.09 Mn
Mar 31, 2022 -57.95 Mn
Dec 31, 2021 -52.91 Mn
Sep 30, 2021 -53.16 Mn
Jun 30, 2021 -44.54 Mn