Revolution Medicines (RVMD) Operating Income (2019 - 2026)
Revolution Medicines' (RVMD) quarterly Operating Income came in at -$445.2 million in Q1 2026, down 84.92% year-on-year from -$3.0 billion in Q1 2025, and down 23.12% quarter-over-quarter from -$361.6 million in Q4 2025.
Revolution Medicines (RVMD) Operating Income (2019 - 2026) Analysis & Trends
Revolution Medicines' Operating Income history runs 8 years deep, the most recent figure standing at -$445.2 million for Q1 2026.
- On a quarterly basis, Operating Income fell 84.92% year-over-year to -$445.2 million in Q1 2026; TTM through Mar 2026 was -$1.4 billion, a 75.68% decrease from a year earlier, with the FY2025 full-year figure at -$1.2 billion, down 71.48% from the prior year.
- Operating Income slipped to -$445.2 million in Q1 2026 per RVMD's latest filing, from -$361.6 million in the prior quarter.
- Across five years, Operating Income topped out at -$57.9 million in Q1 2022 and bottomed at -$445.2 million in Q1 2026.
- The 5-year median for Operating Income is -$156.6 million (2024), against an average of -$180.2 million.
- Across the five-year window, Operating Income decreased 16.62% in 2022 and plunged 191.67% in 2023, its largest moves.
- Year by year, Operating Income stood at -$61.7 million in 2022, then plunged by 191.67% to -$180.0 million in 2023, then dropped by 20.18% to -$216.3 million in 2024, then slumped by 67.18% to -$361.6 million in 2025, then retreated by 23.12% to -$445.2 million in 2026.
- Per Business Quant, the three latest RVMD Operating Income figures stand at -$445.2 million (Q1 2026), -$361.6 million (Q4 2025), and -$315.3 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Alnylam Pharmaceuticals | 36.08 Bn | 33.07 Bn | 959.66 Mn | 268.64 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -445.22 Mn |
| Dec 31, 2025 | -361.63 Mn |
| Sep 30, 2025 | -315.27 Mn |
| Jun 30, 2025 | -264.71 Mn |
| Mar 31, 2025 | -240.76 Mn |
| Dec 31, 2024 | -216.31 Mn |
| Sep 30, 2024 | -175.71 Mn |
| Jun 30, 2024 | -156.64 Mn |
| Mar 31, 2024 | -140.86 Mn |
| Dec 31, 2023 | -179.98 Mn |
| Sep 30, 2023 | -123.25 Mn |
| Jun 30, 2023 | -108.80 Mn |
| Mar 31, 2023 | -75.16 Mn |
| Dec 31, 2022 | -61.71 Mn |
| Sep 30, 2022 | -76.53 Mn |
| Jun 30, 2022 | -62.09 Mn |
| Mar 31, 2022 | -57.95 Mn |
| Dec 31, 2021 | -52.91 Mn |
| Sep 30, 2021 | -53.16 Mn |
| Jun 30, 2021 | -44.54 Mn |