Insmed (INSM) Operating Income (2010 - 2026)

Insmed (INSM) recorded quarterly Operating Income of -$153.3 million in Q1 2026, up 52.05% quarter-over-quarter from -$319.7 million in Q4 2025, and up 38.21% on a YoY basis from -$110.9 million in Q1 2025.

Insmed (INSM) Operating Income (2010 - 2026) Analysis & Trends

Insmed's Operating Income history runs 17 years deep, the most recent figure standing at -$153.3 million for Q1 2026.

  • In Q1 2026, Operating Income rose 38.21% year-over-year to -$153.3 million; the TTM figure through Mar 2026 stood at -$1.2 billion (down 17.44% YoY), while the FY2025 annual figure was -$1.2 billion, down 41.96% from the prior year.
  • Operating Income was -$153.3 million for Q1 2026 at Insmed, up from -$319.7 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$88.3 million in Q2 2022 to a low of -$366.0 million in Q3 2025.
  • Historically, Operating Income has averaged -$202.7 million across 5 years, with a median of -$178.3 million in 2023.
  • The sharpest annual moves came in 2023 and 2026: Operating Income slumped 166.69% in 2023, then soared 38.21% in 2026.
  • A 5-year view of Operating Income shows it stood at -$151.5 million in 2022, then slipped by 17.69% to -$178.3 million in 2023, then slipped by 29.25% to -$230.4 million in 2024, then plunged by 38.77% to -$319.7 million in 2025, then surged by 52.05% to -$153.3 million in 2026.
  • The last three Operating Income figures came in at -$153.3 million (Q1 2026), -$319.7 million (Q4 2025), and -$366.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -2.97 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -15.76 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.82 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.71 Bn 91.71 Bn - -65.83 Mn
10 Insmed 19.79 Bn 18.57 Bn 258.54 Mn -153.32 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -153.32 Mn
Dec 31, 2025 -319.75 Mn
Sep 30, 2025 -366.01 Mn
Jun 30, 2025 -312.88 Mn
Mar 31, 2025 -248.14 Mn
Dec 31, 2024 -230.41 Mn
Sep 30, 2024 -213.43 Mn
Jun 30, 2024 -288.90 Mn
Mar 31, 2024 -145.51 Mn
Dec 31, 2023 -178.27 Mn
Sep 30, 2023 -147.67 Mn
Jun 30, 2023 -235.53 Mn
Mar 31, 2023 -148.16 Mn
Dec 31, 2022 -151.48 Mn
Sep 30, 2022 -127.70 Mn
Jun 30, 2022 -88.32 Mn
Mar 31, 2022 -89.83 Mn
Dec 31, 2021 -99.08 Mn
Sep 30, 2021 -103.62 Mn
Jun 30, 2021 -88.57 Mn