Insmed (INSM) Operating Income (2010 - 2026)
Insmed (INSM) recorded quarterly Operating Income of -$153.3 million in Q1 2026, up 52.05% quarter-over-quarter from -$319.7 million in Q4 2025, and up 38.21% on a YoY basis from -$110.9 million in Q1 2025.
Insmed (INSM) Operating Income (2010 - 2026) Analysis & Trends
Insmed's Operating Income history runs 17 years deep, the most recent figure standing at -$153.3 million for Q1 2026.
- In Q1 2026, Operating Income rose 38.21% year-over-year to -$153.3 million; the TTM figure through Mar 2026 stood at -$1.2 billion (down 17.44% YoY), while the FY2025 annual figure was -$1.2 billion, down 41.96% from the prior year.
- Operating Income was -$153.3 million for Q1 2026 at Insmed, up from -$319.7 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$88.3 million in Q2 2022 to a low of -$366.0 million in Q3 2025.
- Historically, Operating Income has averaged -$202.7 million across 5 years, with a median of -$178.3 million in 2023.
- The sharpest annual moves came in 2023 and 2026: Operating Income slumped 166.69% in 2023, then soared 38.21% in 2026.
- A 5-year view of Operating Income shows it stood at -$151.5 million in 2022, then slipped by 17.69% to -$178.3 million in 2023, then slipped by 29.25% to -$230.4 million in 2024, then plunged by 38.77% to -$319.7 million in 2025, then surged by 52.05% to -$153.3 million in 2026.
- The last three Operating Income figures came in at -$153.3 million (Q1 2026), -$319.7 million (Q4 2025), and -$366.0 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | -15.76 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | -65.83 Mn |
| 10 | Insmed | 19.79 Bn | 18.57 Bn | 258.54 Mn | -153.32 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -153.32 Mn |
| Dec 31, 2025 | -319.75 Mn |
| Sep 30, 2025 | -366.01 Mn |
| Jun 30, 2025 | -312.88 Mn |
| Mar 31, 2025 | -248.14 Mn |
| Dec 31, 2024 | -230.41 Mn |
| Sep 30, 2024 | -213.43 Mn |
| Jun 30, 2024 | -288.90 Mn |
| Mar 31, 2024 | -145.51 Mn |
| Dec 31, 2023 | -178.27 Mn |
| Sep 30, 2023 | -147.67 Mn |
| Jun 30, 2023 | -235.53 Mn |
| Mar 31, 2023 | -148.16 Mn |
| Dec 31, 2022 | -151.48 Mn |
| Sep 30, 2022 | -127.70 Mn |
| Jun 30, 2022 | -88.32 Mn |
| Mar 31, 2022 | -89.83 Mn |
| Dec 31, 2021 | -99.08 Mn |
| Sep 30, 2021 | -103.62 Mn |
| Jun 30, 2021 | -88.57 Mn |