BeOne Medicines (ONC) Operating Income (2015 - 2026)

BeOne Medicines (ONC) posted quarterly Operating Income of $249.9 million for Q1 2026, up 2150.96% year-over-year from $11.1 million in Q1 2025, and up 35.06% quarter-over-quarter from $185.0 million in Q4 2025.

BeOne Medicines (ONC) Operating Income (2015 - 2026) Analysis & Trends

BeOne Medicines (ONC) has reported Operating Income for 12 consecutive years, with $249.9 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Income rose 2150.96% year-over-year to $249.9 million; the TTM figure through Mar 2026 stood at $685.9 million (up 331.93% YoY), while the FY2025 annual figure was $447.1 million, up 178.69% from the prior year.
  • Operating Income climbed to $249.9 million in Q1 2026 per ONC's latest filing, from $185.0 million in the prior quarter.
  • Across five years, Operating Income topped out at $249.9 million in Q1 2026 and bottomed at -$468.6 million in Q4 2022.
  • Historically, Operating Income has averaged -$168.7 million across 5 years, with a median of -$134.0 million in 2023.
  • Annual changes were most pronounced in 2022 — Operating Income tumbled 731.76% — and 2026, when it soared 2150.96%.
  • BeOne Medicines' Operating Income stood at -$468.6 million in 2022, then advanced by 18.1% to -$383.8 million in 2023, then jumped by 79.31% to -$79.4 million in 2024, then jumped by 332.97% to $185.0 million in 2025, then soared by 35.06% to $249.9 million in 2026.
  • Business Quant data shows ONC's Operating Income at $249.9 million in Q1 2026, $185.0 million in Q4 2025, and $163.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Roivant Sciences 26.16 Bn 26.85 Bn 1.16 Mn -365.99 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 325.05 Mn
Mar 31, 2026 249.90 Mn
Dec 31, 2025 185.04 Mn
Sep 30, 2025 163.11 Mn
Jun 30, 2025 87.89 Mn
Mar 31, 2025 11.10 Mn
Dec 31, 2024 -79.43 Mn
Sep 30, 2024 -120.27 Mn
Jun 30, 2024 -107.16 Mn
Mar 31, 2024 -261.35 Mn
Dec 31, 2023 -383.80 Mn
Sep 30, 2023 -133.97 Mn
Jun 30, 2023 -318.72 Mn
Mar 31, 2023 -371.26 Mn
Dec 31, 2022 -468.62 Mn
Sep 30, 2022 -438.36 Mn
Jun 30, 2022 -439.40 Mn
Mar 31, 2022 -443.29 Mn
Dec 31, 2021 190.56 Mn
Sep 30, 2021 -462.33 Mn