Sionna Therapeutics (SION) Operating Expenses (2024 - 2026)

Sionna Therapeutics (SION) posted Operating Expenses of $29.6 million for Q1 2026, up 25.36% sequentially from $23.6 million in Q4 2025, and up 50.56% YoY from $19.7 million in Q1 2025.

Sionna Therapeutics (SION) Operating Expenses (2024 - 2026) Analysis & Trends

Sionna Therapeutics has reported Operating Expenses for 3 years, with the latest figure at $29.6 million in Q1 2026.

  • Quarterly Operating Expenses rose 50.56% year-over-year to $29.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $98.9 million (up 28.36% YoY) and the FY2025 annual result came in at $89.0 million, up 26.12% from the prior year.
  • Operating Expenses advanced to $29.6 million in Q1 2026 per SION's latest filing, from $23.6 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $29.6 million in Q1 2026 and troughed at $11.3 million in Q2 2024.
  • A 3-year average of $21.0 million and a median of $21.9 million in 2025 frame the typical range for Operating Expenses.
  • The widest YoY moves for Operating Expenses: up 94.0% in 2025, down 14.93% in 2025.
  • Over 3 years, Operating Expenses stood at $18.1 million in 2024, then jumped by 30.22% to $23.6 million in 2025, then rose by 25.36% to $29.6 million in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $29.6 million, $23.6 million, and $23.8 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 2.89 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.21 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 4,978.15
7 Royalty Pharma 33.72 Bn 35.84 Bn - 541.02 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.06 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 427.03 Mn
10 Sionna Therapeutics 291.76 Mn 291.76 Mn - 32.47 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 32.47 Mn
Mar 31, 2026 29.60 Mn
Dec 31, 2025 23.61 Mn
Sep 30, 2025 23.81 Mn
Jun 30, 2025 21.91 Mn
Mar 31, 2025 19.66 Mn
Dec 31, 2024 18.13 Mn
Sep 30, 2024 27.98 Mn
Jun 30, 2024 11.29 Mn
Mar 31, 2024 13.15 Mn