Scilex Holding (SCLXW) Operating Margin (2022 - 2026)

Scilex Holding (SCLXW) recorded quarterly Operating Margin of 374.06% in Q1 2026, up 83.7% quarter-over-quarter from 2295.25% in Q4 2025, and up 18390.0% on a YoY basis from N/an in Q1 2025.

Scilex Holding (SCLXW) Operating Margin (2022 - 2026) Analysis & Trends

Scilex Holding's Operating Margin history runs 5 years deep, the most recent figure standing at 374.06% for Q1 2026.

  • In Q1 2026, Operating Margin rose 18390.0% year-over-year to 374.06%; the TTM figure through Mar 2026 stood at 1033.39% (down 85232.0% YoY), while the FY2025 annual figure was 1141.94%, down 99457.0% from the prior year.
  • Operating Margin was 374.06% for Q1 2026 at Scilex Holding, up from 2295.25% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 93.31% in Q3 2022 to a low of 2295.25% in Q4 2025.
  • Historically, Operating Margin has averaged 428.13% across 5 years, with a median of 181.32% in 2023.
  • The sharpest annual moves came in 2024 and 2025: Operating Margin soared 24559 bps in 2024, then tumbled 210479 bps in 2025.
  • A 5-year view of Operating Margin shows it stood at 165.63% in 2022, then gained by 18 bps to 136.23% in 2023, then tumbled by 40 bps to 190.46% in 2024, then tumbled by 1105 bps to 2295.25% in 2025, then soared by 84 bps to 374.06% in 2026.
  • The last three Operating Margin figures came in at 374.06% (Q1 2026), 2295.25% (Q4 2025), and 1766.21% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Gsk 92,316,836.42 Bn 92,316,831.46 Bn 7.76 Bn 30.06%
2 Eli Lilly 983.57 Bn 978.29 Bn 16.22 Bn 47.98%
3 Johnson & Johnson 553.56 Bn 531.50 Bn 15.96 Bn 26.44%
4 AbbVie 383.35 Bn 374.00 Bn 10.78 Bn 26.60%
5 Merck 281.71 Bn 276.06 Bn 12.09 Bn -47.46%
6 Amgen 182.20 Bn 170.16 Bn 5.87 Bn 30.94%
7 Gilead Sciences 153.71 Bn 145.98 Bn 5.52 Bn 37.16%
8 Pfizer 143.75 Bn 130.98 Bn -1.21 Bn -286.83%
9 Bristol Myers Squibb 109.71 Bn 99.25 Bn 8.07 Bn -1.58%
10 Scilex Holding - - 4.15 Mn -374.06%

Historic Data

Download Data
DateValue
Mar 31, 2026 -374.06%
Dec 31, 2025 -2,295.25%
Sep 30, 2025 -1,766.21%
Jun 30, 2025 -207.23%
Mar 31, 2025 -557.96%
Dec 31, 2024 -190.46%
Sep 30, 2024 -137.97%
Jun 30, 2024 -95.44%
Mar 31, 2024 -178.96%
Dec 31, 2023 -136.23%
Sep 30, 2023 -383.56%
Jun 30, 2023 -181.32%
Mar 31, 2023 -240.72%
Dec 31, 2022 -165.63%
Sep 30, 2022 -93.31%
Jun 30, 2022 -144.73%
Mar 31, 2022 -129.27%