Rhythm Pharmaceuticals (RYTM) Return on Sales (2021 - 2026)

Rhythm Pharmaceuticals (RYTM) posted quarterly Return on Sales of 0.01% for Q1 2026, up 1.0% year-over-year from 0.01% in Q1 2025, and down 11.46% quarter-over-quarter from 0.01% in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Return on Sales (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has reported Return on Sales for 6 consecutive years, with 0.01% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Sales rose 1.0% year-over-year to 0.01%; the TTM figure through Mar 2026 stood at 0.01% (changed 0.0% YoY), while the FY2025 annual figure was 0.01%, up 1.0% from the prior year.
  • Return on Sales retreated to 0.01% in Q1 2026 per RYTM's latest filing, from 0.01% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.05% in Q4 2022 and bottomed at 0.37% in Q1 2022.
  • Historically, Return on Sales has averaged 0.04% across 5 years, with a median of 0.02% in 2025.
  • On a YoY basis, Return on Sales climbed as much as 124 bps in 2022 and fell as far as 1287 bps in 2022.
  • Rhythm Pharmaceuticals' Return on Sales stood at 0.05% in 2022, then plunged by 133 bps to 0.02% in 2023, then soared by 40 bps to 0.01% in 2024, then increased by 20 bps to 0.01% in 2025, then declined by 11 bps to 0.01% in 2026.
  • Business Quant data shows RYTM's Return on Sales at 0.01% in Q1 2026, 0.01% in Q4 2025, and 0.01% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Rhythm Pharmaceuticals 7.95 Bn 7.62 Bn 62.32 Mn -0.01%

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.01%
Mar 31, 2026 -0.01%
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.01%
Jun 30, 2025 -0.01%
Mar 31, 2025 -0.02%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.01%
Jun 30, 2024 -0.01%
Mar 31, 2024 -0.05%
Dec 31, 2023 -0.02%
Sep 30, 2023 -0.02%
Jun 30, 2023 -0.02%
Mar 31, 2023 -0.05%
Dec 31, 2022 0.05%
Sep 30, 2022 -0.10%
Jun 30, 2022 -0.05%
Mar 31, 2022 -0.37%
Dec 31, 2021 -0.30%
Sep 30, 2021 -0.37%