Rhythm Pharmaceuticals (RYTM) Return on Sales (2021 - 2026)

Rhythm Pharmaceuticals (RYTM) reported Return on Sales of 0.01% for Q1 2026, up 1.0% year-over-year from 0.01% in Q1 2025, and down 11.55% quarter-over-quarter from 0.01% in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Return on Sales (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 6 years of Return on Sales data on file, last reported at 0.01% in Q1 2026.

  • Return on Sales for Q1 2026 came in at 0.01%, up 1.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 0.01% (changed 0.0% YoY), and the FY2025 annual result was 0.01%, up 1.0% from the prior year.
  • Return on Sales fell to 0.01% in Q1 2026 per RYTM's latest filing, from 0.01% in the prior quarter.
  • Over five years, Return on Sales peaked at 0.05% in Q4 2022 and troughed at 0.35% in Q1 2022.
  • A 5-year average of 0.04% and a median of 0.02% in 2025 frame the typical range for Return on Sales.
  • On a YoY basis, Return on Sales climbed as much as 124 bps in 2022 and fell as far as 1285 bps in 2022.
  • A 5-year view of Return on Sales shows it stood at 0.05% in 2022, then tumbled by 133 bps to 0.02% in 2023, then surged by 40 bps to 0.01% in 2024, then grew by 20 bps to 0.01% in 2025, then dropped by 12 bps to 0.01% in 2026.
  • Business Quant data shows RYTM's Return on Sales at 0.01% in Q1 2026, 0.01% in Q4 2025, and 0.01% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.00%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 0.00%
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 0.00%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Rhythm Pharmaceuticals 6.59 Bn 6.25 Bn 52.96 Mn -0.01%

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.01%
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.01%
Jun 30, 2025 -0.01%
Mar 31, 2025 -0.02%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.01%
Jun 30, 2024 -0.01%
Mar 31, 2024 -0.05%
Dec 31, 2023 -0.02%
Sep 30, 2023 -0.02%
Jun 30, 2023 -0.02%
Mar 31, 2023 -0.05%
Dec 31, 2022 0.05%
Sep 30, 2022 -0.10%
Jun 30, 2022 -0.05%
Mar 31, 2022 -0.35%
Dec 31, 2021 -0.28%
Sep 30, 2021 -0.34%
Jun 30, 2021 -1.29%