Rhythm Pharmaceuticals RYTM Institutional Ownership

NASDAQ RYTM

$102.54 -2.35 (-2.24%)

As of: Sep 4, 2026 · 11:49 AM EDT

Institutions by Trading Activity

305 Institutions

Increased 171 56.1%

Unchanged 34 11.1%

Reduced 100 32.8%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

113.36%

▲+3.79 pp QoQ

Shares Held by Institutions

77.76Mn

of 68.59Mn outstanding

▲+8.73% QoQ

Shares Outstanding

68.59Mn

-9.17Mn held outside 13F filers

Institutional Investors

305

filed 13F for Jun 2026

▲+20 vs prior quarter

Net Shares Added (QoQ)

+6.24Mn

accumulated since last quarter

Value of Holdings

$8.16Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) has 305 institutional investors that have filed 13F reports for the period ending June 2026.

They owned 113.4% of outstanding stock in June 2026, up from 109.6% the prior quarter.
They increased total shares held in Rhythm Pharmaceuticals by 8.73% from last quarter, and the number of investors in RYTM increased 33.77% annually.
Activity in RYTM broke down as 171 buyers, 100 sellers, and 34 unchanged among 305 total holders.
Institutional investors collectively held 77.76Mn shares in Rhythm Pharmaceuticals as of June 2026, up by 6.24Mn shares quarter on quarter, and up 10.22Mn shares year over year.
RA CAPITAL MANAGEMENT, L.P. is the top holder of Rhythm Pharmaceuticals as of June 30, 2026, with 6.67Mn shares representing 9.72% of outstanding stock.
Top purchasers of RYTM stock for the quarter ending June 2026 included Jpmorgan Chase & Co (1.1Mn), Jupiter Topco LLC (925.49K), PRICE T ROWE ASSOCIATES INC /MD/ (911.3K), NORGES BANK (685.84K), Sixth Street Partners Management Company, L.P. (552.74K).
The largest sellers of Rhythm Pharmaceuticals for the quarter ending June 2026 were FMR LLC (663.83K), Point72 Asset Management, L.P. (432.59K), ADAGE CAPITAL PARTNERS GP, L.L.C. (328.74K), Logos Global Management LP (325.0K), DRIEHAUS CAPITAL MANAGEMENT LLC (307.26K).
Business Quant data shows the 10 biggest positions in Rhythm Pharmaceuticals as of June 2026 are held by RA CAPITAL MANAGEMENT, L.P. (6.67Mn), BlackRock, Inc. (6.16Mn), BAKER BROS. ADVISORS LP (5.6Mn), PRIMECAP MANAGEMENT CO/CA/ (3.17Mn), VANGUARD PORTFOLIO MANAGEMENT LLC (3.14Mn), VANGUARD CAPITAL MANAGEMENT LLC (3.01Mn), Jpmorgan Chase & Co (2.65Mn), PERCEPTIVE ADVISORS LLC (2.59Mn), State Street Corp (2.57Mn), PRICE T ROWE ASSOCIATES INC /MD/ (2.57Mn).

Form 13F Holdings

305 Institutional Holders

Report period 30 Jun, 2026

Total shares held 77.76Mn

Of outstanding 113.36%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	RA CAPITAL MANAGEMENT, L.P.	0001346824	6,666,837	9.72%	0	0.00%	$740.22Mn
2	BlackRock, Inc.	0002012383	6,156,902	8.98%	▼80,249	-1.29%	$683.60Mn
3	BAKER BROS. ADVISORS LP	0001263508	5,604,483	8.17%	0	0.00%	$622.27Mn
4	PRIMECAP MANAGEMENT CO/CA/	0000763212	3,168,853	4.62%	▼248,656	-7.28%	$351.84Mn
5	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	3,136,895	4.57%	▲96,177	+3.16%	$348.29Mn
6	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	3,005,977	4.38%	▲38,152	+1.29%	$333.75Mn
7	Jpmorgan Chase & Co	0000019617	2,652,746	3.87%	▲1,099,102	+70.74%	$292.18Mn
8	PERCEPTIVE ADVISORS LLC	0001224962	2,586,295	3.77%	▲212,500	+8.95%	$287.16Mn
9	State Street Corp	0000093751	2,573,529	3.75%	▲301,678	+13.28%	$285.73Mn
10	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	2,566,171	3.74%	▲911,295	+55.07%	$284.92K
11	WESTFIELD CAPITAL MANAGEMENT CO LP	0001177719	2,208,595	3.22%	▲279,472	+14.49%	$245.22Mn
12	Goldman Sachs Group Inc	0000886982	2,126,502	3.10%	▲161,070	+8.20%	$236.11Mn
13	Federated Hermes, Inc.	0001056288	1,785,716	2.60%	▲499,413	+38.83%	$198.27Mn
14	Polar Capital Holdings Plc	0001837309	1,663,632	2.43%	▲48,046	+2.97%	$184.71Mn
15	GEODE CAPITAL MANAGEMENT, LLC	0001214717	1,533,698	2.24%	▲117,429	+8.29%	$170.32Mn
16	Capital Research Global Investors	0001422848	1,532,303	2.23%	▲416,843	+37.37%	$170.13Mn
17	CITADEL ADVISORS LLC	0001423053	1,263,652	1.84%	▼154,967	-10.92%	$140.30Mn
18	Checkpoint Capital L.P.	0001977548	1,186,000	1.73%	▼41,200	-3.36%	$131.68Mn
19	Siren, L.L.C.	0002005245	1,136,275	1.66%	▲410,764	+56.62%	$126.16Mn
20	Morgan Stanley	0000895421	1,112,240	1.62%	▲408,262	+57.99%	$123.49Mn

Showing 1 to 20 of 305 holders