Rhythm Pharmaceuticals (RYTM) Return on Capital Employed (2017 - 2026)

Rhythm Pharmaceuticals (RYTM) posted quarterly Return on Capital Employed of 55.12% for Q1 2026, up 705.0% year-over-year from 6.85% in Q1 2025, and down 11.27% quarter-over-quarter from 49.54% in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Return on Capital Employed (2017 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has reported Return on Capital Employed for 10 consecutive years, with 55.12% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Capital Employed rose 705.0% year-over-year to 55.12%; the TTM figure through Mar 2026 stood at 55.12% (up 705.0% YoY), while the FY2025 annual figure was 58.14%, up 4936.0% from the prior year.
  • Return on Capital Employed declined to 55.12% in Q1 2026 per RYTM's latest filing, from 49.54% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 49.54% in Q4 2025 and bottomed at 112.49% in Q1 2024.
  • Historically, Return on Capital Employed has averaged 71.87% across 5 years, with a median of 64.08% in 2023.
  • Annual changes were most pronounced in 2024 — Return on Capital Employed plunged 5621 bps — and 2025, when it surged 5164 bps.
  • Rhythm Pharmaceuticals' Return on Capital Employed stood at 51.74% in 2022, then decreased by 24 bps to 63.95% in 2023, then slumped by 58 bps to 101.18% in 2024, then soared by 51 bps to 49.54% in 2025, then slipped by 11 bps to 55.12% in 2026.
  • Business Quant data shows RYTM's Return on Capital Employed at 55.12% in Q1 2026, 49.54% in Q4 2025, and 55.5% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 10.74%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -55.45%
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -0.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 7.88%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 26.09%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -50.93%
10 Rhythm Pharmaceuticals 7.95 Bn 7.62 Bn 62.32 Mn -63.45%

Historic Data

Download Data
DateValue
Jun 30, 2026 -63.45%
Mar 31, 2026 -55.12%
Dec 31, 2025 -49.54%
Sep 30, 2025 -55.50%
Jun 30, 2025 -70.90%
Mar 31, 2025 -62.17%
Dec 31, 2024 -101.18%
Sep 30, 2024 -96.51%
Jun 30, 2024 -100.02%
Mar 31, 2024 -112.49%
Dec 31, 2023 -63.95%
Sep 30, 2023 -65.69%
Jun 30, 2023 -64.08%
Mar 31, 2023 -56.28%
Dec 31, 2022 -51.74%
Sep 30, 2022 -62.57%
Jun 30, 2022 -81.55%
Mar 31, 2022 -72.47%
Dec 31, 2021 -56.83%
Sep 30, 2021 -44.21%