Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026)
Rhythm Pharmaceuticals (RYTM) posted Gross Margin of 86.79% for Q3 2026, down 2.49 percentage points from 89.28% a year earlier and down 0.67 percentage points from the prior quarter.
Powered by 
Analysis
Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026) Analysis & Trends
For the trailing twelve months through Sep 30, 2026, Gross Margin at Rhythm Pharmaceuticals was 88.23%, down 1.18 percentage points year-over-year; for FY2025, it came in at 89.73%, unchanged from FY2024.
- Annual Gross Margin shows a four-year change of +8.72 percentage points (FY2021 to FY2025).
- In prior years, Rhythm Pharmaceuticals' Gross Margin was 89.73% in FY2024 (+1.74 pp), 87.99% in FY2023 (-2.99 pp), 90.98% in FY2022 (+9.97 pp) and 81.01% in FY2021.
- The Q3 2026 figure stands as the lowest quarterly Gross Margin since Q4 2023.
- On a year-over-year basis, Gross Margin has declined in each of the last three quarters, with an average year-over-year change of -0.03 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Gross Margin in the past five years was Q2 2022, with a gain of 45.83 percentage points; the weakest was Q2 2023, with a drop of 7.46 percentage points.
- According to Business Quant data, Gross Margin for the three prior quarters was 87.47% (Q2 2026), 88.09% (Q1 2026) and 91.61% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,264.65 Bn | 1,238.27 Bn | 20.46 Bn | 83.88% |
| 2 | Johnson & Johnson | 677.74 Bn | 597.60 Bn | 17.30 Bn | 68.12% |
| 3 | AbbVie | 517.10 Bn | 485.11 Bn | 13.12 Bn | 75.38% |
| 4 | Merck | 362.23 Bn | 325.17 Bn | 13.19 Bn | 72.95% |
| 5 | Novartis Ag | 315.90 Bn | 276.16 Bn | 11.24 Bn | 78.02% |
| 6 | Astrazeneca | 289.40 Bn | 266.24 Bn | 12.86 Bn | 83.60% |
| 7 | Amgen | 249.90 Bn | 201.56 Bn | 7.58 Bn | 73.10% |
| 8 | Gilead Sciences | 209.15 Bn | 184.26 Bn | 6.73 Bn | 81.07% |
| 9 | Pfizer | 165.88 Bn | 113.23 Bn | 12.56 Bn | 75.71% |
| 10 | Rhythm Pharmaceuticals | 7.86 Bn | 6.48 Bn | 79.96 Mn | 86.79% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 86.79% |
| Jun 30, 2026 | 87.47% |
| Mar 31, 2026 | 88.09% |
| Dec 31, 2025 | 91.61% |
| Sep 30, 2025 | 89.28% |
| Jun 30, 2025 | 88.57% |
| Mar 31, 2025 | 88.85% |
| Dec 31, 2024 | 90.95% |
| Sep 30, 2024 | 88.49% |
| Jun 30, 2024 | 89.87% |
| Mar 31, 2024 | 89.19% |
| Dec 31, 2023 | 86.66% |
| Sep 30, 2023 | 89.28% |
| Jun 30, 2023 | 88.37% |
| Mar 31, 2023 | 87.61% |
| Dec 31, 2022 | 88.30% |
| Sep 30, 2022 | 88.40% |
| Jun 30, 2022 | 95.83% |
| Mar 31, 2022 | 84.65% |
| Dec 31, 2021 | 87.01% |
API Access
Rhythm Pharmaceuticals Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=RYTM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "RYTM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=RYTM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();