Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026)
Rhythm Pharmaceuticals (RYTM) reported Gross Margin of 88.09% for Q1 2026, down 75.0% year-over-year from 352.38% in Q1 2025, and down 3.84% quarter-over-quarter from 91.61% in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 6 years of Gross Margin data on file, last reported at 88.09% in Q1 2026.
- Gross Margin for Q1 2026 came in at 88.09%, down 75.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 89.41% (down 21.0% YoY), and the FY2025 annual result was 89.73%, changed 0.0% from the prior year.
- Gross Margin declined to 88.09% in Q1 2026 per RYTM's latest filing, from 91.61% in the prior quarter.
- Over five years, Gross Margin peaked at 112.77% in Q4 2022 and troughed at 84.65% in Q1 2022.
- A 5-year average of 90.5% and a median of 88.85% in 2025 frame the typical range for Gross Margin.
- The sharpest annual moves came in 2022 and 2023: Gross Margin surged 4583 bps in 2022, then slumped 2611 bps in 2023.
- A 5-year view of Gross Margin shows it stood at 112.77% in 2022, then retreated by 23 bps to 86.66% in 2023, then grew by 5 bps to 90.95% in 2024, then advanced by 1 bps to 91.61% in 2025, then dropped by 4 bps to 88.09% in 2026.
- Business Quant data shows RYTM's Gross Margin at 88.09% in Q1 2026, 91.61% in Q4 2025, and 89.28% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Rhythm Pharmaceuticals | 6.59 Bn | 6.25 Bn | 52.96 Mn | 88.09% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 88.09% |
| Dec 31, 2025 | 91.61% |
| Sep 30, 2025 | 89.28% |
| Jun 30, 2025 | 88.57% |
| Mar 31, 2025 | 88.85% |
| Dec 31, 2024 | 90.95% |
| Sep 30, 2024 | 88.49% |
| Jun 30, 2024 | 89.87% |
| Mar 31, 2024 | 89.19% |
| Dec 31, 2023 | 86.66% |
| Sep 30, 2023 | 89.28% |
| Jun 30, 2023 | 88.37% |
| Mar 31, 2023 | 87.61% |
| Dec 31, 2022 | 112.77% |
| Sep 30, 2022 | 88.40% |
| Jun 30, 2022 | 95.83% |
| Mar 31, 2022 | 84.65% |
| Dec 31, 2021 | 87.01% |
| Sep 30, 2021 | 78.40% |
| Jun 30, 2021 | 50.00% |