Growth Metrics

Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2025)

Rhythm Pharmaceuticals (RYTM) has disclosed Gross Margin for 5 consecutive years, with 91.61% as the latest value for Q4 2025.

  • On a quarterly basis, Gross Margin rose 67.0% to 91.61% in Q4 2025 year-over-year; TTM through Dec 2025 was 89.73%, a 0.0% change, with the full-year FY2025 number at 89.73%, changed 0.0% from a year prior.
  • Gross Margin was 91.61% for Q4 2025 at Rhythm Pharmaceuticals, up from 89.28% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 112.77% in Q4 2022 to a low of 50.0% in Q2 2021.
  • A 5-year average of 87.11% and a median of 88.53% in 2021 define the central range for Gross Margin.
  • Peak YoY movement for Gross Margin: surged 3365bps in 2022, then crashed -2611bps in 2023.
  • Rhythm Pharmaceuticals' Gross Margin stood at 87.01% in 2021, then increased by 30bps to 112.77% in 2022, then decreased by -23bps to 86.66% in 2023, then increased by 5bps to 90.95% in 2024, then rose by 1bps to 91.61% in 2025.
  • Per Business Quant, the three most recent readings for RYTM's Gross Margin are 91.61% (Q4 2025), 89.28% (Q3 2025), and 88.57% (Q2 2025).