Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026)

Rhythm Pharmaceuticals' (RYTM) quarterly Gross Margin came in at 88.09% in Q1 2026, down 75.0% year-on-year from 352.38% in Q1 2025, and down 3.84% on a QoQ basis from 91.61% in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 6 years of Gross Margin data on file, last reported at 88.09% in Q1 2026.

  • On a quarterly basis, Gross Margin fell 75.0% year-over-year to 88.09% in Q1 2026; TTM through Mar 2026 was 89.41%, a 21.0% decrease from a year earlier, with the FY2025 full-year figure at 89.73%, changed 0.0% from the prior year.
  • Gross Margin for Q1 2026 stood at 88.09%, down from 91.61% in the prior quarter.
  • Over the last five years, Gross Margin for RYTM reached as high as 112.77% in Q4 2022 and fell as low as 84.65% in Q1 2022.
  • Historically, Gross Margin has averaged 90.5% across 5 years, with a median of 88.85% in 2025.
  • Across the five-year window, Gross Margin soared 4583 bps in 2022 and plunged 2611 bps in 2023, its largest moves.
  • Year by year, Gross Margin stood at 112.77% in 2022, then dropped by 23 bps to 86.66% in 2023, then gained by 5 bps to 90.95% in 2024, then increased by 1 bps to 91.61% in 2025, then retreated by 4 bps to 88.09% in 2026.
  • Per Business Quant data, the three most recent Gross Margin figures were 88.09% in Q1 2026, 91.61% in Q4 2025, and 89.28% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 88.95%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 91.79%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 90.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Rhythm Pharmaceuticals 6.98 Bn 6.64 Bn 52.96 Mn 88.09%

Historic Data

Download Data
DateValue
Mar 31, 2026 88.09%
Dec 31, 2025 91.61%
Sep 30, 2025 89.28%
Jun 30, 2025 88.57%
Mar 31, 2025 88.85%
Dec 31, 2024 90.95%
Sep 30, 2024 88.49%
Jun 30, 2024 89.87%
Mar 31, 2024 89.19%
Dec 31, 2023 86.66%
Sep 30, 2023 89.28%
Jun 30, 2023 88.37%
Mar 31, 2023 87.61%
Dec 31, 2022 112.77%
Sep 30, 2022 88.40%
Jun 30, 2022 95.83%
Mar 31, 2022 84.65%
Dec 31, 2021 87.01%
Sep 30, 2021 78.40%
Jun 30, 2021 50.00%