Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026)
Rhythm Pharmaceuticals' (RYTM) quarterly Gross Margin came in at 88.09% in Q1 2026, down 75.0% year-on-year from 352.38% in Q1 2025, and down 3.84% on a QoQ basis from 91.61% in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 6 years of Gross Margin data on file, last reported at 88.09% in Q1 2026.
- On a quarterly basis, Gross Margin fell 75.0% year-over-year to 88.09% in Q1 2026; TTM through Mar 2026 was 89.41%, a 21.0% decrease from a year earlier, with the FY2025 full-year figure at 89.73%, changed 0.0% from the prior year.
- Gross Margin for Q1 2026 stood at 88.09%, down from 91.61% in the prior quarter.
- Over the last five years, Gross Margin for RYTM reached as high as 112.77% in Q4 2022 and fell as low as 84.65% in Q1 2022.
- Historically, Gross Margin has averaged 90.5% across 5 years, with a median of 88.85% in 2025.
- Across the five-year window, Gross Margin soared 4583 bps in 2022 and plunged 2611 bps in 2023, its largest moves.
- Year by year, Gross Margin stood at 112.77% in 2022, then dropped by 23 bps to 86.66% in 2023, then gained by 5 bps to 90.95% in 2024, then increased by 1 bps to 91.61% in 2025, then retreated by 4 bps to 88.09% in 2026.
- Per Business Quant data, the three most recent Gross Margin figures were 88.09% in Q1 2026, 91.61% in Q4 2025, and 89.28% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 88.95% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 90.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Rhythm Pharmaceuticals | 6.98 Bn | 6.64 Bn | 52.96 Mn | 88.09% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 88.09% |
| Dec 31, 2025 | 91.61% |
| Sep 30, 2025 | 89.28% |
| Jun 30, 2025 | 88.57% |
| Mar 31, 2025 | 88.85% |
| Dec 31, 2024 | 90.95% |
| Sep 30, 2024 | 88.49% |
| Jun 30, 2024 | 89.87% |
| Mar 31, 2024 | 89.19% |
| Dec 31, 2023 | 86.66% |
| Sep 30, 2023 | 89.28% |
| Jun 30, 2023 | 88.37% |
| Mar 31, 2023 | 87.61% |
| Dec 31, 2022 | 112.77% |
| Sep 30, 2022 | 88.40% |
| Jun 30, 2022 | 95.83% |
| Mar 31, 2022 | 84.65% |
| Dec 31, 2021 | 87.01% |
| Sep 30, 2021 | 78.40% |
| Jun 30, 2021 | 50.00% |