Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026)

Rhythm Pharmaceuticals (RYTM) reported Gross Margin of 88.09% for Q1 2026, down 75.0% year-over-year from 352.38% in Q1 2025, and down 3.84% quarter-over-quarter from 91.61% in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Gross Margin (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 6 years of Gross Margin data on file, last reported at 88.09% in Q1 2026.

  • Gross Margin for Q1 2026 came in at 88.09%, down 75.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 89.41% (down 21.0% YoY), and the FY2025 annual result was 89.73%, changed 0.0% from the prior year.
  • Gross Margin declined to 88.09% in Q1 2026 per RYTM's latest filing, from 91.61% in the prior quarter.
  • Over five years, Gross Margin peaked at 112.77% in Q4 2022 and troughed at 84.65% in Q1 2022.
  • A 5-year average of 90.5% and a median of 88.85% in 2025 frame the typical range for Gross Margin.
  • The sharpest annual moves came in 2022 and 2023: Gross Margin surged 4583 bps in 2022, then slumped 2611 bps in 2023.
  • A 5-year view of Gross Margin shows it stood at 112.77% in 2022, then retreated by 23 bps to 86.66% in 2023, then grew by 5 bps to 90.95% in 2024, then advanced by 1 bps to 91.61% in 2025, then dropped by 4 bps to 88.09% in 2026.
  • Business Quant data shows RYTM's Gross Margin at 88.09% in Q1 2026, 91.61% in Q4 2025, and 89.28% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Rhythm Pharmaceuticals 6.59 Bn 6.25 Bn 52.96 Mn 88.09%

Historic Data

Download Data
DateValue
Mar 31, 2026 88.09%
Dec 31, 2025 91.61%
Sep 30, 2025 89.28%
Jun 30, 2025 88.57%
Mar 31, 2025 88.85%
Dec 31, 2024 90.95%
Sep 30, 2024 88.49%
Jun 30, 2024 89.87%
Mar 31, 2024 89.19%
Dec 31, 2023 86.66%
Sep 30, 2023 89.28%
Jun 30, 2023 88.37%
Mar 31, 2023 87.61%
Dec 31, 2022 112.77%
Sep 30, 2022 88.40%
Jun 30, 2022 95.83%
Mar 31, 2022 84.65%
Dec 31, 2021 87.01%
Sep 30, 2021 78.40%
Jun 30, 2021 50.00%