Relay Therapeutics (RLAY) Operating Margin (2021 - 2026)

Relay Therapeutics (RLAY) reported Operating Margin of 2619.67% for Q1 2026, down 151446.0% year-over-year from N/an in Q1 2025, and down 202.45% on a QoQ basis from 866.14% in Q4 2025.

Relay Therapeutics (RLAY) has 6 years of Operating Margin data on file, last reported at 2619.67% in Q1 2026.

  • Quarterly Operating Margin fell 151446.0% year-over-year to 2619.67% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 2776.6% (up 200233.0% YoY) and the FY2025 annual result came in at 1971.59%, up 175048.0% from the prior year.
  • Operating Margin slipped to 2619.67% in Q1 2026 per RLAY's latest filing, from 866.14% in the prior quarter.
  • Across five years, Operating Margin topped out at 9219600.0% in Q4 2023 and bottomed at 89117.65% in Q2 2023.
  • The 5-year median for Operating Margin is 11351.11% (2025), against an average of 690655.84%.
  • Peak annual rise in Operating Margin reached 924839486 bps in 2023, while the deepest fall reached 6779956 bps in 2023.
  • Tracing RLAY's Operating Margin over 5 years: stood at 28794.86% in 2022, then jumped by 32118 bps to 9219600.0% in 2023, then slumped by 100 bps to 903.0% in 2024, then grew by 4 bps to 866.14% in 2025, then tumbled by 202 bps to 2619.67% in 2026.
  • Per Business Quant, the three latest RLAY Operating Margin figures stand at 2619.67% (Q1 2026), 866.14% (Q4 2025), and 11351.11% (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 23.02%
10 Relay Therapeutics 2.53 Bn 2.53 Bn - -2,619.67%

Historic Data

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DateValue
Mar 31, 2026 -2,619.67%
Dec 31, 2025 -866.14%
Jun 30, 2025 -11,351.11%
Mar 31, 2025 -1,105.21%
Mar 31, 2024 -903.00%
Dec 31, 2023 9,219,600.00%
Sep 30, 2023 -291.95%
Jun 30, 2023 -89,117.65%
Mar 31, 2023 -44,768.58%
Dec 31, 2022 -28,794.86%
Sep 30, 2022 -24,968.60%
Jun 30, 2022 -21,318.08%
Mar 31, 2022 -14,969.21%
Dec 31, 2021 -11,944.09%
Sep 30, 2021 -9,157.66%
Jun 30, 2021 -22,936.02%
Mar 31, 2021 -4,454.31%