Growth Metrics

Ultragenyx Pharmaceutical (RARE) Operating Expenses (2013 - 2026)

Ultragenyx Pharmaceutical (RARE) reported Operating Expenses of $305.0 million for Q1 2026, up 8.16% year-over-year from $282.0 million in Q1 2025, and down 4.85% on a QoQ basis from $320.6 million in Q4 2025.

Ultragenyx Pharmaceutical (RARE) has 14 years of Operating Expenses data on file, last reported at $305.0 million in Q1 2026.

  • Quarterly Operating Expenses rose 8.16% year-over-year to $305.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $1.2 billion (up 11.5% YoY) and the FY2025 annual result came in at $1.2 billion, up 10.22% from the prior year.
  • Operating Expenses fell to $305.0 million in Q1 2026 per RARE's latest filing, from $320.6 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $330.8 million in Q3 2025 and bottomed at $216.6 million in Q1 2022.
  • The 5-year median for Operating Expenses is $271.5 million (2024), against an average of $272.0 million.
  • The widest annual swing landed in 2022, when Operating Expenses soared 84.15%; it then declined 23.0% in 2023.
  • Tracing RARE's Operating Expenses over 5 years: stood at $249.0 million in 2022, then grew by 0.0% to $249.0 million in 2023, then climbed by 15.25% to $287.0 million in 2024, then gained by 11.71% to $320.6 million in 2025, then decreased by 4.85% to $305.0 million in 2026.
  • Per Business Quant, the three latest RARE Operating Expenses figures stand at $305.0 million (Q1 2026), $320.6 million (Q4 2025), and $330.8 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Ultragenyx Pharmaceutical 2.29 Bn 1.89 Bn 106.00 Mn 305.00 Mn

Historic Data

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DateValue
Mar 31, 2026 305.00 Mn
Dec 31, 2025 320.56 Mn
Sep 30, 2025 330.82 Mn
Jun 30, 2025 274.38 Mn
Mar 31, 2025 282.00 Mn
Dec 31, 2024 286.95 Mn
Sep 30, 2024 271.48 Mn
Jun 30, 2024 263.39 Mn
Mar 31, 2024 274.18 Mn
Dec 31, 2023 248.98 Mn
Sep 30, 2023 243.15 Mn
Jun 30, 2023 256.27 Mn
Mar 31, 2023 254.60 Mn
Dec 31, 2022 248.98 Mn
Sep 30, 2022 315.77 Mn
Jun 30, 2022 230.94 Mn
Mar 31, 2022 216.57 Mn
Dec 31, 2021 185.95 Mn
Sep 30, 2021 171.48 Mn
Jun 30, 2021 169.75 Mn
Mar 31, 2021 205.96 Mn
Dec 31, 2020 187.62 Mn
Sep 30, 2020 131.79 Mn
Jun 30, 2020 124.76 Mn
Mar 31, 2020 156.97 Mn
Dec 31, 2019 130.05 Mn
Sep 30, 2019 143.83 Mn
Jun 30, 2019 136.62 Mn
Mar 31, 2019 117.39 Mn
Dec 31, 2018 106.60 Mn
Sep 30, 2018 101.41 Mn
Jun 30, 2018 107.69 Mn
Mar 31, 2018 107.16 Mn
Dec 31, 2017 99.25 Mn
Sep 30, 2017 83.91 Mn
Jun 30, 2017 78.44 Mn
Mar 31, 2017 69.95 Mn
Dec 31, 2016 70.55 Mn
Sep 30, 2016 65.89 Mn
Jun 30, 2016 58.07 Mn
Mar 31, 2016 53.62 Mn
Dec 31, 2015 56.16 Mn
Sep 30, 2015 39.94 Mn
Jun 30, 2015 30.14 Mn
Mar 31, 2015 21.50 Mn
Dec 31, 2014 16.94 Mn
Sep 30, 2014 15.84 Mn
Jun 30, 2014 13.66 Mn
Mar 31, 2014 10.34 Mn
Dec 31, 2013 9.53 Mn
Sep 30, 2013 7.76 Mn
Jun 30, 2013 8.25 Mn
Mar 31, 2013 6.75 Mn