Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026)

Ultragenyx Pharmaceutical (RARE) reported Gross Margin of 77.94% for Q1 2026, down 120.0% year-over-year from 389.71% in Q1 2025, and down 9.2% quarter-over-quarter from 85.84% in Q4 2025.

Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026) Analysis & Trends

Ultragenyx Pharmaceutical (RARE) has 9 years of Gross Margin data on file, last reported at 77.94% in Q1 2026.

  • Gross Margin for Q1 2026 came in at 77.94%, down 120.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 83.52% (down 149.0% YoY), and the FY2025 annual result was 83.8%, down 245.0% from the prior year.
  • Gross Margin slipped to 77.94% in Q1 2026 per RARE's latest filing, from 85.84% in the prior quarter.
  • Over five years, Gross Margin peaked at 94.85% in Q4 2022 and troughed at 77.94% in Q1 2026.
  • A 5-year average of 87.18% and a median of 87.8% in 2023 frame the typical range for Gross Margin.
  • The sharpest annual moves came in 2022 and 2025: Gross Margin slumped 565 bps in 2022, then surged 66 bps in 2025.
  • A 5-year view of Gross Margin shows it stood at 94.85% in 2022, then fell by 4 bps to 90.69% in 2023, then slipped by 1 bps to 89.57% in 2024, then fell by 4 bps to 85.84% in 2025, then fell by 9 bps to 77.94% in 2026.
  • Business Quant data shows RARE's Gross Margin at 77.94% in Q1 2026, 85.84% in Q4 2025, and 82.5% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Ultragenyx Pharmaceutical 2.77 Bn 2.36 Bn 106.00 Mn 77.94%

Historic Data

Download Data
DateValue
Mar 31, 2026 77.94%
Dec 31, 2025 85.84%
Sep 30, 2025 82.50%
Jun 30, 2025 86.18%
Mar 31, 2025 79.14%
Dec 31, 2024 89.57%
Sep 30, 2024 84.93%
Jun 30, 2024 85.53%
Mar 31, 2024 83.89%
Dec 31, 2023 90.69%
Sep 30, 2023 88.79%
Jun 30, 2023 90.85%
Mar 31, 2023 87.80%
Dec 31, 2022 94.85%
Sep 30, 2022 90.48%
Jun 30, 2022 90.74%
Mar 31, 2022 92.37%
Dec 31, 2021 95.79%
Sep 30, 2021 94.89%
Jun 30, 2021 96.39%