Growth Metrics

Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2025)

Ultragenyx Pharmaceutical (RARE) has disclosed Gross Margin for 8 consecutive years, with 85.84% as the latest value for Q4 2025.

  • On a quarterly basis, Gross Margin fell 373.0% to 85.84% in Q4 2025 year-over-year; TTM through Dec 2025 was 83.8%, a 245.0% decrease, with the full-year FY2025 number at 83.8%, down 245.0% from a year prior.
  • Gross Margin was 85.84% for Q4 2025 at Ultragenyx Pharmaceutical, up from 82.5% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 96.39% in Q2 2021 to a low of 79.42% in Q1 2025.
  • A 5-year average of 89.32% and a median of 90.03% in 2022 define the central range for Gross Margin.
  • Peak YoY movement for Gross Margin: surged 443bps in 2021, then plummeted -565bps in 2022.
  • Ultragenyx Pharmaceutical's Gross Margin stood at 95.79% in 2021, then dropped by -1bps to 94.85% in 2022, then dropped by -4bps to 90.69% in 2023, then dropped by -1bps to 89.57% in 2024, then dropped by -4bps to 85.84% in 2025.
  • Per Business Quant, the three most recent readings for RARE's Gross Margin are 85.84% (Q4 2025), 82.5% (Q3 2025), and 86.18% (Q2 2025).