Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026)
Ultragenyx Pharmaceutical's (RARE) quarterly Gross Margin came in at 77.94% in Q1 2026, down 120.0% year-on-year from 389.71% in Q1 2025, and down 9.2% on a QoQ basis from 85.84% in Q4 2025.
Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026) Analysis & Trends
Ultragenyx Pharmaceutical (RARE) has 9 years of Gross Margin data on file, last reported at 77.94% in Q1 2026.
- On a quarterly basis, Gross Margin fell 120.0% year-over-year to 77.94% in Q1 2026; TTM through Mar 2026 was 83.52%, a 149.0% decrease from a year earlier, with the FY2025 full-year figure at 83.8%, down 245.0% from the prior year.
- Gross Margin for Q1 2026 stood at 77.94%, down from 85.84% in the prior quarter.
- Over the last five years, Gross Margin for RARE reached as high as 94.85% in Q4 2022 and fell as low as 77.94% in Q1 2026.
- Historically, Gross Margin has averaged 87.18% across 5 years, with a median of 87.8% in 2023.
- Across the five-year window, Gross Margin plunged 565 bps in 2022 and soared 66 bps in 2025, its largest moves.
- Year by year, Gross Margin stood at 94.85% in 2022, then slipped by 4 bps to 90.69% in 2023, then fell by 1 bps to 89.57% in 2024, then slipped by 4 bps to 85.84% in 2025, then slipped by 9 bps to 77.94% in 2026.
- Per Business Quant data, the three most recent Gross Margin figures were 77.94% in Q1 2026, 85.84% in Q4 2025, and 82.5% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 88.95% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 90.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Ultragenyx Pharmaceutical | 2.72 Bn | 2.31 Bn | 106.00 Mn | 77.94% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 77.94% |
| Dec 31, 2025 | 85.84% |
| Sep 30, 2025 | 82.50% |
| Jun 30, 2025 | 86.18% |
| Mar 31, 2025 | 79.14% |
| Dec 31, 2024 | 89.57% |
| Sep 30, 2024 | 84.93% |
| Jun 30, 2024 | 85.53% |
| Mar 31, 2024 | 83.89% |
| Dec 31, 2023 | 90.69% |
| Sep 30, 2023 | 88.79% |
| Jun 30, 2023 | 90.85% |
| Mar 31, 2023 | 87.80% |
| Dec 31, 2022 | 94.85% |
| Sep 30, 2022 | 90.48% |
| Jun 30, 2022 | 90.74% |
| Mar 31, 2022 | 92.37% |
| Dec 31, 2021 | 95.79% |
| Sep 30, 2021 | 94.89% |
| Jun 30, 2021 | 96.39% |