Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026)
Ultragenyx Pharmaceutical (RARE) reported Gross Margin of 77.94% for Q1 2026, down 120.0% year-over-year from 389.71% in Q1 2025, and down 9.2% quarter-over-quarter from 85.84% in Q4 2025.
Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026) Analysis & Trends
Ultragenyx Pharmaceutical (RARE) has 9 years of Gross Margin data on file, last reported at 77.94% in Q1 2026.
- Gross Margin for Q1 2026 came in at 77.94%, down 120.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 83.52% (down 149.0% YoY), and the FY2025 annual result was 83.8%, down 245.0% from the prior year.
- Gross Margin slipped to 77.94% in Q1 2026 per RARE's latest filing, from 85.84% in the prior quarter.
- Over five years, Gross Margin peaked at 94.85% in Q4 2022 and troughed at 77.94% in Q1 2026.
- A 5-year average of 87.18% and a median of 87.8% in 2023 frame the typical range for Gross Margin.
- The sharpest annual moves came in 2022 and 2025: Gross Margin slumped 565 bps in 2022, then surged 66 bps in 2025.
- A 5-year view of Gross Margin shows it stood at 94.85% in 2022, then fell by 4 bps to 90.69% in 2023, then slipped by 1 bps to 89.57% in 2024, then fell by 4 bps to 85.84% in 2025, then fell by 9 bps to 77.94% in 2026.
- Business Quant data shows RARE's Gross Margin at 77.94% in Q1 2026, 85.84% in Q4 2025, and 82.5% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Ultragenyx Pharmaceutical | 2.77 Bn | 2.36 Bn | 106.00 Mn | 77.94% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 77.94% |
| Dec 31, 2025 | 85.84% |
| Sep 30, 2025 | 82.50% |
| Jun 30, 2025 | 86.18% |
| Mar 31, 2025 | 79.14% |
| Dec 31, 2024 | 89.57% |
| Sep 30, 2024 | 84.93% |
| Jun 30, 2024 | 85.53% |
| Mar 31, 2024 | 83.89% |
| Dec 31, 2023 | 90.69% |
| Sep 30, 2023 | 88.79% |
| Jun 30, 2023 | 90.85% |
| Mar 31, 2023 | 87.80% |
| Dec 31, 2022 | 94.85% |
| Sep 30, 2022 | 90.48% |
| Jun 30, 2022 | 90.74% |
| Mar 31, 2022 | 92.37% |
| Dec 31, 2021 | 95.79% |
| Sep 30, 2021 | 94.89% |
| Jun 30, 2021 | 96.39% |