Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026)
Ultragenyx Pharmaceutical's Gross Margin came in at 84.11% for Q2 2026, down 2.12 percentage points from 86.23% a year earlier but up 6.17 percentage points from the prior quarter.
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Analysis
Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Ultragenyx Pharmaceutical reported Gross Margin of 83.08%, down 2.14 percentage points year-over-year; for FY2025, it was 83.80%, down 2.45 percentage points from FY2024.
- Gross Margin has declined in each of the last five years, with a five-year change of -13.93 percentage points (FY2020 to FY2025).
- Going back by year, Gross Margin was 86.25% in FY2024 (-3.38 pp), 89.63% in FY2023 (-2.57 pp), 92.21% in FY2022 (-3.24 pp) and 95.44% in FY2021 (-2.29 pp).
- The five-year range for quarterly Gross Margin is 77.94% (Q1 2026) to 95.79% (Q4 2021).
- Year-over-year, Gross Margin has declined for four consecutive quarters, with an average year-over-year change of -2.31 percentage points over the last eight quarters.
- The fastest year-over-year change in Gross Margin over five years came in Q4 2021 (a gain of 1.78 percentage points), and the weakest in Q2 2022 (a drop of 5.65 percentage points).
- Business Quant data shows RARE's Gross Margin at 77.94% (Q1 2026), 85.84% (Q4 2025) and 82.50% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 68.19% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 74.74% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 73.54% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 78.02% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 83.60% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 72.04% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | 79.76% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 72.78% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 85.33% |
| 10 | Ultragenyx Pharmaceutical | 1.51 Bn | -292.70 Mn | 180.00 Mn | 84.11% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 84.11% |
| Mar 31, 2026 | 77.94% |
| Dec 31, 2025 | 85.84% |
| Sep 30, 2025 | 82.50% |
| Jun 30, 2025 | 86.23% |
| Mar 31, 2025 | 79.14% |
| Dec 31, 2024 | 89.57% |
| Sep 30, 2024 | 84.93% |
| Jun 30, 2024 | 85.53% |
| Mar 31, 2024 | 83.89% |
| Dec 31, 2023 | 90.69% |
| Sep 30, 2023 | 88.79% |
| Jun 30, 2023 | 90.85% |
| Mar 31, 2023 | 87.80% |
| Dec 31, 2022 | 94.85% |
| Sep 30, 2022 | 90.48% |
| Jun 30, 2022 | 90.74% |
| Mar 31, 2022 | 92.37% |
| Dec 31, 2021 | 95.79% |
| Sep 30, 2021 | 94.89% |
API Access
Ultragenyx Pharmaceutical Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=RARE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "RARE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=RARE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();