Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026)

Ultragenyx Pharmaceutical's (RARE) quarterly Gross Margin came in at 77.94% in Q1 2026, down 120.0% year-on-year from 389.71% in Q1 2025, and down 9.2% on a QoQ basis from 85.84% in Q4 2025.

Ultragenyx Pharmaceutical (RARE) Gross Margin (2018 - 2026) Analysis & Trends

Ultragenyx Pharmaceutical (RARE) has 9 years of Gross Margin data on file, last reported at 77.94% in Q1 2026.

  • On a quarterly basis, Gross Margin fell 120.0% year-over-year to 77.94% in Q1 2026; TTM through Mar 2026 was 83.52%, a 149.0% decrease from a year earlier, with the FY2025 full-year figure at 83.8%, down 245.0% from the prior year.
  • Gross Margin for Q1 2026 stood at 77.94%, down from 85.84% in the prior quarter.
  • Over the last five years, Gross Margin for RARE reached as high as 94.85% in Q4 2022 and fell as low as 77.94% in Q1 2026.
  • Historically, Gross Margin has averaged 87.18% across 5 years, with a median of 87.8% in 2023.
  • Across the five-year window, Gross Margin plunged 565 bps in 2022 and soared 66 bps in 2025, its largest moves.
  • Year by year, Gross Margin stood at 94.85% in 2022, then slipped by 4 bps to 90.69% in 2023, then fell by 1 bps to 89.57% in 2024, then slipped by 4 bps to 85.84% in 2025, then slipped by 9 bps to 77.94% in 2026.
  • Per Business Quant data, the three most recent Gross Margin figures were 77.94% in Q1 2026, 85.84% in Q4 2025, and 82.5% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 88.95%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 91.79%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 90.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Ultragenyx Pharmaceutical 2.72 Bn 2.31 Bn 106.00 Mn 77.94%

Historic Data

Download Data
DateValue
Mar 31, 2026 77.94%
Dec 31, 2025 85.84%
Sep 30, 2025 82.50%
Jun 30, 2025 86.18%
Mar 31, 2025 79.14%
Dec 31, 2024 89.57%
Sep 30, 2024 84.93%
Jun 30, 2024 85.53%
Mar 31, 2024 83.89%
Dec 31, 2023 90.69%
Sep 30, 2023 88.79%
Jun 30, 2023 90.85%
Mar 31, 2023 87.80%
Dec 31, 2022 94.85%
Sep 30, 2022 90.48%
Jun 30, 2022 90.74%
Mar 31, 2022 92.37%
Dec 31, 2021 95.79%
Sep 30, 2021 94.89%
Jun 30, 2021 96.39%